Haemostatic Agents, Sealants, and Adhesives

  • Ian Eardley


Hemorrhage is an occupational hazard for all surgeons, and there are several basic surgical techniques to combat it, including manual pressure, tourniquet, cerclage, ligature, suture, and diathermy. There are occasions, however, when such methods fail. In recent years, the use of topical hemostatic agents has increased, with an ever-increasing array of agents being commercially available. Definition of the actions of the different agents is valuable and is important from a regulatory perspective:


Platelet Activation Tranexamic Acid Clotting Cascade Fibrin Sealant Contact Activation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

  1. Oz MC, Rondinone JF, Shargil NS. Floseal matrix: new generation topical haemostatic agent. J Card Surg. 2003;18:486–93.PubMedCrossRefGoogle Scholar
  2. Seyednejad H, Imani M, Jamieson T, Seifalian AM. Topical haemostatic agents. Br J Surg. 2008;95:1197–225.PubMedCrossRefGoogle Scholar
  3. Spotnitz W. Fibrin sealant, past present and future. A brief review. World J Surg. 2010;34:632–4.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 2012

Authors and Affiliations

  1. 1.Department of UrologySt James’s University HospitalLeedsUK

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