Cardiac Electrophysiology

  • Paul D. Morris
  • Jonathan Sahu


This chapter provides a review of cardiac myocyte electrophysiology, including the ­molecular mechanisms and tissue adaptations underlying the generation, propagation and control of electrical impulses in the heart. There is a brief review of key clinical subject areas such as the ECG and implantable pacemaker therapies. The pathological mechanisms behind arrhythmia are covered, along with a brief description of the catheter-based electrophysiological studies and therapies, which can be used to diagnose and treat cardiac rhythm disturbances.


Ion channels Electrophysiology Pacemaker Electrocardiogram Autonomic nervous system Action potential Ablation Arrhythmia Automaticity 

Further Reading

  1. Berne RM, Levy MN. Cardiovascular physiology: Mosby’s physiology monograph series. 8th ed. St. Louis: Mosby; 2000.Google Scholar
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  3. Camm JA, Luscher TF, Serruys PW. The ESC textbook of ­cardiovascular medicine. 2nd ed. Oxford: Oxford University Press; 2009.Google Scholar
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  7. Josephson ME. Clinical cardiac electrophysiology: techniques and interpretations. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2008.Google Scholar
  8. Levick JR. An introduction to cardiovascular physiology. 5th ed. London: Hodder Arnold; 2010.Google Scholar
  9. Zipes DP, Jalife J. Cardiac electrophysiology: from cell to bedside. 5th ed. Philadelphia: Elsevier Saunders; 2009.Google Scholar

Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  1. 1.Department of CardiologySheffield Teaching Hospitals NHS Foundation TrustSheffieldUK

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