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Success and Anticipated Pregnancy Outcomes for Oocyte and Embryo Donation

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Abstract

Almost three decades ago, oocyte and embryo donation became an option for women who had experienced unsuccessful fertility treatments or were not candidates for other assisted reproductive technologies. Women with surgical or natural menopause, diminished ovarian reserve, premature ovarian failure, recurrent pregnancy loss, poor ovarian response to stimulation, or carriers of an inheritable disorder were provided with a new option for fertility. Women that were previously considered sterile were now able to have successful pregnancy and childbirth.

What originated in the cattle breeding industry years prior was introduced to human patients in 1983. Originally, the technique relied on embryo transfer after uterine lavage of the donor. The naturally cycling donor underwent intrauterine insemination from the partner of the recipient. After fertilization, the uterus was irrigated with the intent to capture embryos that had not implanted. The embryos would then be replaced into the recipient’s uterus. Buster et al. reported the first successful live birth using the uterine lavage technique. The initial attempts were completed on recipients that still had normal menstrual cycles, therefore not requiring additional hormones.

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Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Stanford University, 900 Welch Road, Suite 350, Palo Alto, CA, 94304, USA

    Candice O’Hern Perfetto M.D.

  2. Department of Obstetrics and Gynecology, Stanford University, 900 Welch Road, Suite 20, Palo Alto, CA, 94304, USA

    Lynn M. Westphal M.D.

Authors
  1. Candice O’Hern Perfetto M.D.
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  2. Lynn M. Westphal M.D.
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Corresponding author

Correspondence to Lynn M. Westphal M.D. .

Editor information

Editors and Affiliations

  1. , Center for Women’s Reproductive Care, Columbia University, 1790 Broadway, New York, 10019, New York, USA

    Mark V. Sauer

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© 2013 Springer-Verlag London

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Perfetto, C.O., Westphal, L.M. (2013). Success and Anticipated Pregnancy Outcomes for Oocyte and Embryo Donation. In: Sauer, M. (eds) Principles of Oocyte and Embryo Donation. Springer, London. https://doi.org/10.1007/978-1-4471-2392-7_3

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  • DOI: https://doi.org/10.1007/978-1-4471-2392-7_3

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2391-0

  • Online ISBN: 978-1-4471-2392-7

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