Abstract
A 66 year old man presents with a two year history of gradually progressive lower limb weakness. The presentation was preceded by symptoms compatible with bilateral carpal tunnel syndrome. Four years before the development of neurological symptoms he had a permanent pacemaker inserted. Amyloid deposits were detected on sural nerve biopsy. A mutation in the transthyretin gene (Val30Met) confirms the diagnosis of Familial amyloid polyneuropathy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Murphy SM, Reilly MM. Amyloid neuropathies. Advances Clin Neurosci Rehabil. 2011;11(1):16–9.
Planté-Bordeneuve V, Said G. Familial amyloid polyneuropathy. Lancet Neurol. 2011;10(12):1086–97.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer-Verlag London Ltd.
About this chapter
Cite this chapter
Mahdi-Rogers, M., Laurá, M., Reilly, M.M. (2017). A Man with a Pacemaker Develops Difficulty Walking. In: Manji, H., Turner, C., Evans, M. (eds) Neuromuscular Disease . Springer, London. https://doi.org/10.1007/978-1-4471-2389-7_14
Download citation
DOI: https://doi.org/10.1007/978-1-4471-2389-7_14
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-2388-0
Online ISBN: 978-1-4471-2389-7
eBook Packages: MedicineMedicine (R0)