Cognitive Assessment

  • A. J. Larner


As with all neurological conditions, the assessment of patients with cognitive complaints begins with history taking and physical examination, of which the former is by far the most important aspect. In addition to the usual semistructured approach (what, when, where, who, how, why?), the importance of obtaining collateral history from a knowledgeable informant cannot be overemphasized (Larner 2005a, b, 2009a). In some centers, a provisional diagnosis of Alzheimer’s disease in predementia stage is based largely on informant report (Burns and Morris 2008). The key question which history taking should seek to answer is whether the account is one of self-reported lapses in memory retrieval in the absence of collateral verification, or an informant report of memory impairment with loss of self-appreciation by the patient, the latter being more in keeping with a neurodegenerative disorder (Burns and Morris 2008: 53; Larner 2011a).


Mild Cognitive Impairment Dementia With Lewy Body MMSE Score Diagnostic Utility Diagnostic Odds Ratio 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag London Limited 2012

Authors and Affiliations

  • A. J. Larner
    • 1
  1. 1.Cognitive Function ClinicWalton Centre for Neurology and NeurosurgeryLiverpoolUK

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