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Why Should We Write a Book on Pediatric Metabolic Syndrome? Commentaries from Worldwide Experts

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Pediatric Metabolic Syndrome

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Abstract

One might ask “why write an entire book on the pediatric metabolic ­syndrome?” It is not operationally defined as of yet, and some even challenge its very existence. However, couched in the current worldwide obesity epidemic, the scientific literature indicates that this constellation of cardiometabolic disease risk factors is increasing in pediatric populations around the world without discrimination by age, sex, or race/ethnicity. This chapter provides unique perspectives from a select group of child health advocates and experts, many who have dedicated significant proportions of their careers, and in some cases their entire career, to pediatric preventative health and nutrition. Here, they provide their candid perspective on the pediatric metabolic syndrome from different positions, yet all emphasize the resolve of the scientific community to continue to pursue this area both in research and clinical care.

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References

  1. Berenson GS. Childhood risk factors predict adult risk associated with subclinical cardiovascular disease. The Bogalusa heart study. Am J Cardiol. 2002;90:3L–7L.

    Article  PubMed  Google Scholar 

  2. Natural history of aortic and coronary atherosclerotic lesions in youth. Findings from the PDAY Study. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Arterioscler Thromb. 1993;13:1291–8. http://atvb.ahajournals.org/content/13/9/1291.long.

    Google Scholar 

  3. Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008;359:61–73.

    Article  PubMed  CAS  Google Scholar 

  4. Chen W, Berenson GS. Metabolic syndrome: definition, and prevalence in children. J Pediatr (Rio J). 2007;83:1–3.

    Article  Google Scholar 

  5. Johnson CC, Nicklas TA, Arbeit ML, Harsha DW, Mott DS, Hunter SM, Wattigney W, Berenson GS. Cardiovascular intervention for high-risk families: the heart smart program. South Med J. 1991;84:1305–12.

    Article  PubMed  CAS  Google Scholar 

  6. Berenson GS, Srinivasan SR, Fernandez C, Chen W, Xu J. Can adult cardiologists play a role in the prevention of heart disease beginning in childhood? Methodist Debakey Cardiovasc J. 2010;6:4–9.

    PubMed  Google Scholar 

  7. Downey AM, Greensberg JS, Virgilio SJ, Berenson GS. Health promotion model for “Heart Smart”: the medical school, university and community. Health Values. 1989;13:31–46.

    PubMed  CAS  Google Scholar 

  8. Berenson GS. Cardiovascular health promotion for children: a model for a Parish (county)-wide program (implementation and preliminary results). Prev Cardiol. 2010;13:23–8.

    Article  PubMed  Google Scholar 

  9. Center for Disease Control and Prevention. Overweight children ages 6–17: increased from 6% in 1976–1980 to 17% in 2005–2006. www.cdc.gov/Features/dsOverweightchildren/. Accessed 30 Sept 2009.

  10. Trust for America’s Health (TFAH). F as in fat: how obesity policies are failing in America, 2009. Washington, DC: Robert Wood Johnson Foundation, Trust for America’s Health; 2009.

    Google Scholar 

  11. Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM. Prevalence of high body mass index in US children and adolescents, 2007–2008. JAMA. 2010;303(3):242–9.

    Article  PubMed  CAS  Google Scholar 

  12. Olshansky SJ, Passaro DJ, et al. A potential decline in life expectancy in the United States in the 21st century. N Engl J Med. 2005;352(11):1138–45.

    Article  PubMed  CAS  Google Scholar 

  13. Nader PR, O’Brien M, et al. Identifying risk for obesity in early childhood. Pediatrics. 2006;118(3):e594–601.

    Article  PubMed  Google Scholar 

  14. Must A, Jacques PF, et al. Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard growth study of 1922 to 1935. N Engl J Med. 1992;327(19):1350–5.

    Article  PubMed  CAS  Google Scholar 

  15. Barker DJ, Osmond C, et al. Trajectories of growth among children who have coronary events as adults. N Engl J Med. 2005;353(17):1802–9.

    Article  PubMed  CAS  Google Scholar 

  16. Leunissen RW, Kerkhof GF, et al. Timing and tempo of first-year rapid growth in relation to cardiovascular and metabolic risk profile in early adulthood. JAMA. 2009;301(21):2234–42.

    Article  PubMed  CAS  Google Scholar 

  17. Brown WV, Fujioka K, et al. Obesity: why be concerned? Am J Med. 2009;122(4 Suppl 1):S4–11.

    PubMed  Google Scholar 

  18. Hossain P, Kawar B, et al. Obesity and diabetes in the developing world—a growing challenge. N Engl J Med. 2007;356(3):213–5.

    Article  PubMed  CAS  Google Scholar 

  19. Wild S, Roglic G, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047–53.

    Article  PubMed  Google Scholar 

  20. Surgeon general report on youth violence. 2001. http://www.surgeongeneral.gov/library/youthviolence/sgsummary/summary.htm. Accessed 1 Oct 2011.

  21. Seeman T, Gruenewald T, et al. Modeling multisystem biological risk in young adults: the coronary artery risk development in young adults study. Am J Hum Biol. 2010;22(4):463–72.

    Article  PubMed  Google Scholar 

  22. McEwen BS, Seeman T. Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Ann N Y Acad Sci. 1999;896:30–47.

    Article  PubMed  CAS  Google Scholar 

  23. Meigs JB, Wilson PW, et al. Prevalence and characteristics of the metabolic syndrome in the San Antonio heart and Framingham offspring studies. Diabetes. 2003;52(8):2160–7.

    Article  PubMed  CAS  Google Scholar 

  24. Cook S, Weitzman M, et al. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988–1994. Arch Pediatr Adolesc Med. 2003;157(8):821–7.

    Article  PubMed  Google Scholar 

  25. Cruz ML, Goran MI. The metabolic syndrome in children and adolescents. Curr Diab Rep. 2004;4(1):53–62.

    Article  PubMed  Google Scholar 

  26. Cruz ML, Weigensberg MJ, et al. The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity. J Clin Endocrinol Metab. 2004;89(1):108–13.

    Article  PubMed  CAS  Google Scholar 

  27. Nemetz PN, Roger VL, et al. Recent trends in the prevalence of coronary disease: a population-based autopsy study of nonnatural deaths. Arch Intern Med. 2008;168(3):264–70.

    Article  PubMed  Google Scholar 

  28. Ford ES, Ajani UA, Croft JB, et al. Explaining the decrease in U.S. deaths from coronary disease, 1980–2000. N Engl J Med. 2007;356:2388–98.

    Article  PubMed  CAS  Google Scholar 

  29. Olshansky SJ, Passaro DJ, Hershow RC, Layden J, Carnes BA, Brody J, Hayflick L, Butler RN, Allison DB, Ludwig DS. A potential decline in life expectancy in the United States in the 21st century. N Engl J Med. 2005;352:1138–45.

    Article  PubMed  CAS  Google Scholar 

  30. Le J, Zhang D, et al. Vascular age is advanced in children with atherosclerosis-promoting risk factors. Circ Cardiovasc Imaging. 2010;3(1):8–14.

    Article  PubMed  Google Scholar 

  31. Berenson GS, Srinivasan SR, et al. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults: the Bogalusa heart study. N Eng J Med. 1998;338(23):1650–6.

    Article  CAS  Google Scholar 

  32. Emerging Risk Factors Collaboration, Seshasai SR, et al. Diabetes mellitus, fasting glucose and risk of cause-specific death. N Engl J Med. 2011;364(9):829–41.

    Article  PubMed  CAS  Google Scholar 

  33. Centers for Disease Control and Prevention. U.S. Obesity Trends by State, 1985–2009. http://www.cdc.gov/obesity/data/trends.html#State. Accessed 1 Oct 2011.

  34. Roger VL, Go AS, Lloyd-Jones DM, American Heart Association Statistics Committee and Stroke Statistics Subcommittee, et al. Heart disease and stroke statistics–2011 update: a report from the American Heart Association. Circulation. 2011;123(4):e18–209.

    Article  PubMed  Google Scholar 

  35. Lloyd-Jones DM, Hong Y, Labarthe D, et al. Setting national goals for cardiovascular health. Circulation. 2010;121:586–613.

    Article  PubMed  Google Scholar 

  36. Heidenreich PA, Trogdon JG, Khavjou OA, American Heart Association Advocacy Coordinating Committee; Stroke Council; Council on Cardiovascular Radiology and Intervention; Council on Clinical Cardiology; Council on Epidemiology and Prevention; Council on Arteriosclerosis; Thrombosis and Vascular Biology; Council on Cardiopulmonary; Critical Care; Perioperative and Resuscitation; Council on Cardiovascular Nursing; Council on the Kidney in Cardiovascular Disease; Council on Cardiovascular Surgery and Anesthesia, and Interdisciplinary Council on Quality of Care and Outcomes Research, et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation. 2011;123(8):933–44.

    Article  PubMed  Google Scholar 

  37. Sacco RL. Achieving ideal cardiovascular and brain health: opportunity amid crisis: presidential address at the American Heart Association 2010 scientific sessions. Circulation. 2011;123(22):2653–7.

    Article  PubMed  Google Scholar 

  38. Boden-Albala B, Sacco RL, Lee HS, et al. Metabolic syndrome and ischemic stroke risk: Northern Manhattan Study. Stroke. 2008;39(1):30–5.

    Article  PubMed  Google Scholar 

  39. Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of high body mass index in US children and adolescents, 2007–08. JAMA. 2010;303(3):242–9.

    Article  PubMed  CAS  Google Scholar 

  40. Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006;295(13):1549–55.

    Article  PubMed  CAS  Google Scholar 

  41. Harrington JW, Nguyen VQ, Paulson JF, Garland R, Pasquinelli L, Lewis D. Identifying the “tipping point” age for overweight pediatric patients. Clin Pediatr (Phila). 2010;49(7):638–43.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA

    Arthur S. Agatston M.D., FACC (Associate Professor)

  2. Cardiac Prevention Center, Mount Sinai Medical Center, Miami, FL, USA

    Arthur S. Agatston M.D., FACC (Director)

  3. South Beach Diet, Miami Beach, FL, USA

    Arthur S. Agatston M.D., FACC (President and Founder)

  4. Division of General Pediatrics, Monroe Carell, Jr. Children’s Hospital, Vanderbilt University, Nashville, TN, USA

    Shari Barkin M.D., MSHS (Marian Wright Edelman Professor of Pediatrics)

  5. Tulane University, New Orleans, New Orleans, LA, USA

    Gerald S. Berenson M.D. (Chair of Preventative Cardiology, Director for the Center for Cardiovascular Health)

  6. Department of Medicine, Pediatrics, Biochemistry & Epidemiology, Tulane University Health Science Center, New Orleans, LA, USA

    Gerald S. Berenson M.D. (Chair of Preventative Cardiology, Director for the Center for Cardiovascular Health)

  7. The Bogalusa Heart Study, Tulane University Health Science Center, New Orleans, LA, USA

    Gerald S. Berenson M.D. (Principal Investigator)

  8. Children’s Hospital Colorado, Denver, CO, USA

    Stephen R. Daniels M.D., Ph.D. (L. Joseph Butterfi eld Chair in Pediatrics)

  9. Department of Pediatrics Children’s Hospital, University of Colorado, Denver, Aurora, CO, USA

    Stephen R. Daniels M.D., Ph.D. (Professor and Chair)

  10. EcoChamber, Miami, FL, USA

    Tia Diaz-Balart (Founder & President)

  11. Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA, USA

    Matthew W. Gillman M.D., SM (Professor)

  12. Obesity Prevention Program, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA, USA

    Matthew W. Gillman M.D., SM (Professor)

  13. Department of Nutrition, Harvard School of Public Health, Boston, MA, USA

    Matthew W. Gillman M.D., SM (Professor)

  14. Division of Pediatric Gastroenterology, Hepatology and Nutrition, Morgan Stanley Children’s Hospital, New York, NY, USA

    Joel Edward Lavine Ph.D., M.D. (Chief)

  15. Department of Pediatrics, New York Presbyterian Columbia University Medical Center, College of Physicians and Surgeons, Morgan Stanley Children’s Hospital, New York, NY, USA

    Joel Edward Lavine Ph.D., M.D. (Chief)

  16. Department of Pediatrics, CIBC World Markets Children’s Miracle Foundation Chair in Child Health Research, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Brian W. McCrindle M.D., MPH, FRCP(C) (Professor)

  17. Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Andrew N. Redington M.B.B.S., MRCP(UK), M.D., FRCP(UK), FRCP(C) (Professor and BMO Financial Group Chair in Cardiology)

  18. Division of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, ON, Canada

    Andrew N. Redington M.B.B.S., MRCP(UK), M.D., FRCP(UK), FRCP(C) (Professor and BMO Financial Group Chair in Cardiology)

  19. Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA

    Ralph L. Sacco M.D., M.S. (Professor and Chair)

  20. Departments of Neurology, Epidemiology and Public Health, Human Genetics and Neurosurgery, Miami, FL, USA

    Ralph L. Sacco M.D., M.S. (Professor)

  21. Jackson Memorial Hospital, Miami, FL, USA

    Ralph L. Sacco M.D., M.S. (Chief of Neurology Service)

  22. American Heart Association 2011--2012, Dallas, TX, USA

    Ralph L. Sacco M.D., M.S. (President)

  23. University of Miami, Miami, FL, USA

    Donna E. Shalala Ph.D. (President)

  24. Department of Pediatrics, University of Minnesota Amplatz Children’s Hospital, Minneapolis, MN, USA

    Julia Steinberger M.D., M.S. (Professor)

  25. Department of Pediatrics, Environmental Medicine and Health Policy, New York University School of Medicine, New York, NY, USA

    Leonardo Trasande M.D., M.P.P (Associate Professor)

  26. Bipartisan Policy Center, current member, Washington, DC, USA

    Ann M. Veneman B.A., M.A., JD (Previous Secretary)

  27. United States Department of Agriculture, Washington, USA

    Ann M. Veneman B.A., M.A., JD (Previous Secretary)

  28. Department of Pediatrics, Environmental Medicine, and Psychiatry, New York University School of Medicine, New York, NY, USA

    Michael L. Weitzman M.D. (Professor)

Authors
  1. Arthur S. Agatston M.D., FACC
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  2. Arthur S. Agatston M.D., FACC
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  3. Arthur S. Agatston M.D., FACC
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  4. Shari Barkin M.D., MSHS
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  5. Gerald S. Berenson M.D.
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  6. Gerald S. Berenson M.D.
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  7. Stephen R. Daniels M.D., Ph.D.
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  8. Stephen R. Daniels M.D., Ph.D.
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  9. Tia Diaz-Balart
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  10. Matthew W. Gillman M.D., SM
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  11. Joel Edward Lavine Ph.D., M.D.
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  12. Brian W. McCrindle M.D., MPH, FRCP(C)
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  13. Andrew N. Redington M.B.B.S., MRCP(UK), M.D., FRCP(UK), FRCP(C)
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  14. Ralph L. Sacco M.D., M.S.
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  15. Ralph L. Sacco M.D., M.S.
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  16. Ralph L. Sacco M.D., M.S.
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  17. Ralph L. Sacco M.D., M.S.
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  18. Donna E. Shalala Ph.D.
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  19. Julia Steinberger M.D., M.S.
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  20. Leonardo Trasande M.D., M.P.P
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  21. Ann M. Veneman B.A., M.A., JD
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  22. Michael L. Weitzman M.D.
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Editor information

Editors and Affiliations

  1. , Pediatrics, Miller School of Medicine, D820, Miami, 33101-6820, Florida, USA

    Steven E. Lipshultz

  2. , Pediatrics, Miller School of Medicine, 1580 NW 10th Avenue, Miami, 33130, USA

    Sarah E. Messiah

  3. , Pediatrics, Miller School of Medicine, 1580 NW 10th Avenue #123, Miami, 33101, USA

    Tracie L. Miller

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Agatston, A.S. et al. (2012). Why Should We Write a Book on Pediatric Metabolic Syndrome? Commentaries from Worldwide Experts . In: Lipshultz, S., Messiah, S., Miller, T. (eds) Pediatric Metabolic Syndrome. Springer, London. https://doi.org/10.1007/978-1-4471-2366-8_1

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  • DOI: https://doi.org/10.1007/978-1-4471-2366-8_1

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2365-1

  • Online ISBN: 978-1-4471-2366-8

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