Skip to main content
SpringerLink
Log in
Book cover

Diffuse Low-Grade Gliomas in Adults pp 463–473Cite as

Functional Rehabilitation in Patients with Diffuse Low-Grade Glioma (DLGG)

  • Chapter
  • First Online:

  • 1294 Accesses

Abstract

A relevant and ethical management of DLGG patients can’t refrain from taking into account cognitive disorders and proposing, if need be, a specific program of cognitive rehabilitation, to allow patients recovering -or maintaining- the best level of quality of life as possible. The slow-growing and infiltrating character of DLGG makes their associated cognitive disorders particularly amenable to rehabilitation, by potentiating or even constraining the mechanisms of functional brain reorganization within complex large-scale neural networks.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   159.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Taphoorn MJB, Klein M. Cognitive deficits in adult patients with brain tumours. Lancet Neurol. 2004;3: 159–68.

    Article  PubMed  Google Scholar 

  2. Bartolomei F, Bosma I, Klein M, et al. Disturbed functional connectivity in brain tumour patients: evaluation by graph analysis of synchronization matrices. Clin Neurophysiol. 2006;117(9):2039–49.

    Article  PubMed  Google Scholar 

  3. Anderson SW, Damasio H, Tranel D. Neuropsychological impairments associated with lesions caused by tumor or stroke. Arch Neurol. 1990;47(4):397–405.

    Article  PubMed  CAS  Google Scholar 

  4. High WM, Sander AS, Struchen MA, et al. Rehabilitation for traumatic brain injury. New York: Oxford University Press; 2005.

    Google Scholar 

  5. Varona JF, Bermejo F, Guerra JM, et al. Long-term prognosis of ischemic stroke in young adults. Study of 272 cases. J Neurol. 2004;251:1507–14.

    Article  PubMed  CAS  Google Scholar 

  6. Desmurget M, Bonnetblanc F, Duffau H. Contrasting acute and slow-growing lesions: a new door to brain plasticity. Brain. 2007;130:898–914.

    Article  PubMed  Google Scholar 

  7. Duffau H. The “frontal syndrome” revisited: lessons from electrostimulation mapping studies. Cortex. 2012;48:120–31.

    Article  PubMed  Google Scholar 

  8. Plaza M, Gatignol P, Leroy M, et al. Speaking without Broca’s area after tumor resection. Neurocase. 2009;15:294–310.

    Article  PubMed  Google Scholar 

  9. Marciniak CM, Sliwa JA, Allen W, Heinemann AW, et al. Functional outcomes of persons with brain tumors after inpatient rehabilitation. Arch Phys Med Rehabil. 2001;82:457–63.

    Article  PubMed  CAS  Google Scholar 

  10. Giordana MT, Clara E. Functional rehabilitation and brain tumour patients. Neurol Sci. 2006;27:240–4.

    Article  PubMed  CAS  Google Scholar 

  11. Mukand JA, Blackinton DD, Crincoli MG, et al. Incidence of neurologic deficits and rehabilitation of patients with brain tumors. Am J Phys Med Rehabil. 2001;80(5):346–50.

    Article  PubMed  CAS  Google Scholar 

  12. Gehring K, Sitskoorn MM, Aaronson NK, et al. Interventions for cognitive deficits in adults with brain tumors. Lancet Neurol. 2008;7(6):548–60.

    Article  PubMed  Google Scholar 

  13. Gehring K, Sitskoorn MM, Gundy CM, et al. Cognitive rehabilitation in patients with gliomas: a randomized, controlled trial. J Clin Oncol. 2009;27(22):3712–22.

    Article  PubMed  Google Scholar 

  14. Huang ME, Wartella JE, Kreutzer JS. Functional outcomes and quality of life in patients with brain tumors: a preliminary report. Arch Phys Med Rehabil. 2001;82(11):1540–6.

    Article  PubMed  CAS  Google Scholar 

  15. Huang ME, Wartella JE, Kreutzer JS, et al. Functional outcomes and quality of life in patients with brain tumours: a review of the literature. Brain Inj. 2001;15(10):843–56.

    Article  PubMed  CAS  Google Scholar 

  16. Pace A, Parisi C, Di Lelio M, et al. Home rehabilitation for brain tumor patients. J Exp Clin Cancer Res. 2007;26(3):297–300.

    PubMed  CAS  Google Scholar 

  17. Bartolo M, Zucchella C, Pace A, et al. Early rehabilitation after surgery improves functional outcome in inpatients with brain tumours. J Neurooncol. 2012;107(3):537–44.

    Article  PubMed  Google Scholar 

  18. Janda M, Steginga S, Dunn J, et al. Unmet supportive care needs and interest in services among patients with a brain tumour and their carers. Patient Educ Couns. 2008;71(2):251–8.

    Article  PubMed  Google Scholar 

  19. Zangwill OL. Psychological aspects of rehabilitation in cases of brain injury. Br J Psychol Gen Sect. 1947;37(2):60–9.

    Article  PubMed  CAS  Google Scholar 

  20. Prigatano GP. Principles of neuropsychological rehabilitation. New York: Oxford University Press; 1999.

    Google Scholar 

  21. Robertson IH, Murre JM. Rehabilitation of brain damage: brain plasticity and principles of guided recovery. Psychol Bull. 1999;125(5):544–75.

    Article  PubMed  CAS  Google Scholar 

  22. Evans JJ. Memory rehabilitation – should we be aiming for restoration or compensation? J Neurol. 2006;253(4):520–1.

    Article  PubMed  Google Scholar 

  23. Cicerone KD, Dahlberg C, Kalmar K, et al. Evidence-based cognitive rehabilitation: recommendations for clinical practice. Arch Phys Med Rehabil. 2000;81:1596–615.

    Article  PubMed  CAS  Google Scholar 

  24. Luria AR. Restoration of function after brain injury. New York: Pergamon Press; 1963.

    Google Scholar 

  25. Kim YH, Yoo WK, Ko MH, et al. Plasticity of the attentional network after brain injury and cognitive rehabilitation. Neurorehabil Neural Repair. 2009;23(5):468–77.

    Article  PubMed  Google Scholar 

  26. Prigatano GP. In: Halligan PW, Wade DT, editors. A history of cognitive rehabilitation, in effectiveness of rehabilitation for cognitive deficits. New York: Oxford University Press; 2005.

    Google Scholar 

  27. Luria AR, Naydin VL, Tsvetkova LS, et al. Restoration of higher cortical function following local brain damage. In: Vinken PJ, Bruyn GW, editors. Handbook of clinical neurology, vol. 3. Amsterdam: North-Holland Publishing Company; 1969. p. 368–433.

    Google Scholar 

  28. Power JD, Fair DA, Schlaggar BL, et al. The development of human functional brain networks. Neuron. 2010;67:735–48.

    Article  PubMed  CAS  Google Scholar 

  29. Majewska AK, Sur M. Plasticity and specificity of cortical processing networks. Trends Neurosci. 2006;29:323–9.

    Article  PubMed  CAS  Google Scholar 

  30. Vogel AC, Power JD, Petersen SE, et al. Development of brain’s functional network architecture. Neuropsychol Rev. 2010;20:362–75.

    Article  PubMed  Google Scholar 

  31. Murphy TH, Corbett D. Plasticity during stroke recovery: from synapse to behavior. Nat Rev Neurosci. 2009;10:861–72.

    Article  PubMed  CAS  Google Scholar 

  32. Sagi Y, Tavor I, Hofstetter S, et al. Learning in the fast lane: news insight into neuroplasticity. Neuron. 2012;73:1195–203.

    Article  PubMed  CAS  Google Scholar 

  33. Johansen-Berg H, Baptista CS, Thomas AG. Human structural plasticity at record speed. Neuron. 2012;73:1058–60.

    Article  PubMed  CAS  Google Scholar 

  34. Dancause N, Barbay S, Frost FB, et al. Extensive cortical rewiring after brain injury. J Neurosci. 2005;25:10167–79.

    Article  PubMed  CAS  Google Scholar 

  35. Kantak SS, Stinear JW, Buch ER, et al. Rewiring the brain: potential role of the premotor cortex in motor control, learning, and recovery of function following brain injury. Neurorehabil Neural Repair. 2012;26:282–92.

    Article  PubMed  Google Scholar 

  36. Johansen-Berg H. Structural plasticity: rewiring the brain. Curr Biol. 2007;17:141–4.

    Article  Google Scholar 

  37. Klein M, Heimans JJ, Aaronson NK, et al. Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study. Lancet. 2002;360(9343):1361–8.

    Article  PubMed  CAS  Google Scholar 

  38. Duffau H, Capelle L, Denvil D, et al. Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation. J Neurol Neurosurg Psychiatry. 2003;74(7):901–7.

    Article  PubMed  CAS  Google Scholar 

  39. Hebb DO. The organization of behavior: a neuropsychological theory. New York: John Wiley & Sons; 1949.

    Google Scholar 

  40. Thiebaut de Schotten M, Fflytche DH, Bizzi A, et al. Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractography. Neuroimage. 2011;54:49–59.

    Article  PubMed  Google Scholar 

  41. Catani M, Ffychte DH. The rises and falls of disconnection syndromes. Brain. 2005;128:2224–39.

    Article  PubMed  Google Scholar 

  42. Shinoura N, Suzuki Y, Yamada R, et al. Damage to the right superior longitudinal fasciculus in the inferior parietal lobe plays a role in spatial neglect. Neuropsychologia. 2009;47:2600–3.

    Article  PubMed  CAS  Google Scholar 

  43. Duffau H. Does post-lesional subcortical plasticity exist in human brain? Neurosci Res. 2009;21:543–9.

    Google Scholar 

  44. Yogarajah M, Focke NK, Bonelli SB, et al. The structural plasticity of white matter networks following anterior temporal lobe resection. Brain. 2010;133(Pt 8):2348–64.

    Article  PubMed  Google Scholar 

  45. Friston KJ, Frith CD, Fletcher P, et al. Functional topography, multidimensional scaling and functional connectivity in the brain. Cereb Cortex. 1996;6:346–55.

    Article  Google Scholar 

  46. Pievani M, de Haan W, Wu T, et al. Functional network disruption in the degenerative dementias. Lancet Neurol. 2011;10:829–43.

    Article  PubMed  Google Scholar 

  47. Petrella JR, Sheldon FC, Prince SE, et al. Default mode network connectivity in stable vs progressive mild ­cognitive impairment. Neurology. 2011;76:511–7.

    Article  PubMed  CAS  Google Scholar 

  48. Bosma I, Douw L, Bartolomei F, et al. Synchronized brain activity and neurocognitive function in patients with low-grade glioma: a magneto-encephalography study. Neuro Oncol. 2008;10:734–44.

    Article  PubMed  Google Scholar 

  49. Martino J, Honma SM, Findlay AM. Resting functional connectivity in patients with brain tumors in eloquent areas. Ann Neurol. 2011;69:521–32.

    Article  PubMed  Google Scholar 

  50. Caeyenberghs K, Leemans A, Heitger MH, et al. Graph analysis of functional networks for cognitive control of action in traumatic brain injury. Brain. 2012;135:1293–307.

    Article  PubMed  Google Scholar 

  51. Nakamura T, Hilllary FG, Biswal BB. Resting network plasticity following brain injury. PLoS One. 2009;4:e8020.

    Article  Google Scholar 

  52. Mayer AR, Mannel MV, Ling J, et al. Functional connectivity in mild traumatic brain injury. Hum Brain Mapp. 2011;32:1825–35.

    Article  PubMed  Google Scholar 

  53. Castellanos NP, Paùl N, Ordonez VE, et al. Reorganization of functional connectivity as a correlate of cognitive recovery in acquired brain injury. Brain. 2010;133:2365–81.

    Article  PubMed  Google Scholar 

  54. Goldstein K. After effects of brain injuries in war. New York: Grune & Stratton; 1942.

    Google Scholar 

  55. Newcombe F. Very late outcome after focal wartime brain wounds. J Clin Exp Neuropsychol. 1996;18(1):1–23.

    Article  PubMed  CAS  Google Scholar 

  56. Newcombe F, Brooks N, Baddeley A. Rehabilitation after brain damage: an overview. Int Rehabil Med. 1980;2:133–7.

    PubMed  CAS  Google Scholar 

  57. Wilson BA. Cognitive rehabilitation: how it is and how it might be. J Int Neuropsychol Soc. 1997;3:487–96.

    PubMed  CAS  Google Scholar 

  58. Ius T, Angelini E, Thiebautde Schotten M, et al. Evidence for potentials and limitations of brain plasticity using an atlas of functional resectability of WHO grade II gliomas: towards a “minimal common brain”. Neuroimage. 2011;56:992–1000.

    Article  PubMed  Google Scholar 

  59. Vallar G, Bolognini N. Behavioral facilitation following brain stimulation: implications for neurorehabilitation. Neuropsychol Rehabil. 2011;21:618–49.

    Article  PubMed  Google Scholar 

  60. Miniussi C, Vallar G. Brain stimulation and behavioral cognitive rehabilitation: a new tool for ­neurorehabilitation. Neuropsychol Rehabil. 2011;21:553–9.

    Article  PubMed  Google Scholar 

  61. Weiduschat N, Thiel A, Rubi-Fessen I, et al. Effects of repetitive transcranial magnetic stimulation in aphasic stroke: a randomized controlled pilot study. Stroke. 2011;42:409–15.

    Article  PubMed  Google Scholar 

  62. Diaconescu AO, Kramer E, Hermann C, et al. Distinct functional networks associated with improvements of affective symptoms and cognitive function and citalopram treatment in geriatric depression. Hum Brain Mapp. 2011;32:1677–91.

    Article  PubMed  Google Scholar 

  63. Wegbreit E, Ellis JA, Nandam A, et al. Amygdala functional connectivity predicts pharmacotherapy outcome in pediatric bipolar disorder. Brain Connect. 2011;1:411–22.

    Article  PubMed  Google Scholar 

  64. Floel A, Cohen LG. Recovery of function in humans: cortical stimulation and pharmacological treatments after stroke. Neurobiol Dis. 2010;37:243–51.

    Article  PubMed  CAS  Google Scholar 

  65. Winblad B. Piracetam: a review of pharmacological properties and clinical uses. CNS Drug Rev. 2005;11: 169–82.

    Article  PubMed  CAS  Google Scholar 

  66. Goveas JS, Xie C, Ward BD, et al. Recovery of hippocampal network connectivity correlates with cognitive improvement in mild Alzheimer’s disease treated with donepezil assessed by resting-state fMRI. J Magn Reson Imaging. 2011;4:764–73.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Institute for Health and Medical Research (INSERM), U1051, Team “Plasticity of the Central Nervous System, Human Stem Cells and Glial Tumors”, Institute for Neurosciences of Montpellier, Montpellier University Medical Center, 80 Av Augustin Fliche, 34091, Montpellier, France

    Guillaume Herbet & Sylvie Moritz-Gasser

  2. Department of Neurosurgery, Gui de Chauliac Hospital, Montpellier University Medical Center, 80 Av Augustin Fliche, 34295, Montpellier, France

    Guillaume Herbet

  3. Department of Neurology, CHRU Montpellier, Gui de Chauliac Hospital, Montpellier University Medical Center, 80 Avenue Augustin Fliche, 34295, Montpellier, France

    Sylvie Moritz-Gasser

Authors
  1. Guillaume Herbet
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sylvie Moritz-Gasser
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sylvie Moritz-Gasser .

Editor information

Editors and Affiliations

  1. , INSERM U1051, Institute for Neurosciences of Montpelli, av. Augustin Fliche 80, Montpellier, 34295, France

    Hugues Duffau

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag London

About this chapter

Cite this chapter

Herbet, G., Moritz-Gasser, S. (2013). Functional Rehabilitation in Patients with Diffuse Low-Grade Glioma (DLGG). In: Duffau, H. (eds) Diffuse Low-Grade Gliomas in Adults. Springer, London. https://doi.org/10.1007/978-1-4471-2213-5_30

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-2213-5_30

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2212-8

  • Online ISBN: 978-1-4471-2213-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation