Metabolic-Oncological MR Imaging of Diffuse Low-Grade Glioma: A Dynamic Approach

  • Rémy GuillevinEmail author


Today, magnetic resonance imaging is the “gold standard” of brain tumor imaging, but remains widely used only under its conventional aspect. Recent advances on MRI sequences development and use provided a new conceptual approach of diagnosis and follow-up of WHO II glioma based on multiparametrical and dynamic study of their metabolism allowed by spectroscopy (even multinuclear) and perfusion-weighted imaging, namely, oncological biometabolic imaging. We discuss in this chapter the different aspects and methodological issues and address some practical consequences on MRI clinical practice.


MRI Spectroscopy Perfusion Metabolic imaging Metabolism Mathematical modeling 


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© Springer-Verlag London 2013

Authors and Affiliations

  1. 1.Radiology Department and MPIM LaboratoryTeaching Hospital and University of PoitiersPoitiersFrance
  2. 2.Functional Laboratory Imaging, Neuroradiology Department, Teaching HospitalUniversity of PoitiersPoitiersFrance

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