Who Is the Donor?

  • Aleksandar Mijovic
Chapter

Abstract

A woman with high-risk MDS underwent peripheral blood stem cell transplantation from an unrelated male donor with a 9/10 HLA-antigen match. On day +32 after the transplant (a Friday), she was transferred to a local hospital. The discharge letter was faxed to hematology secretarial office. The following day, her hemoglobin was 8.0 g/dl, platelet count 85 × 109/l, and neutrophils 4.1 × 109/l. Two units of leucodepleted red cells were selected for transfusion to the patient. First unit was transfused uneventfully; transfusion was stopped halfway through the second unit, after the intervention of the duty consultant who realized that the units had not been irradiated.

Keywords

Diarrhea Bilirubin Cholestasis Transferase Psoralen 

References

  1. Dwyre DM, Holland PV. Transfusion-associated graft-versus-host disease. Vox Sang. 2008;95:85–93.PubMedCrossRefGoogle Scholar
  2. Klein HG. Transfusion-associated graft-versus-host disease: less fresh blood and more gray (Gy) for an aging population. Transfusion. 2006;46:878–80.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2012

Authors and Affiliations

  • Aleksandar Mijovic
    • 1
  1. 1.Kings College Hospital HaematologyLondonUK

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