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Mohs Micrographic Surgery for the Treatment of Cutaneous Melanoma

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Abstract

Melanoma is a clinically and biologically diverse malignancy for which complete surgical excision offers the only chance for cure. Current guidelines for surgical excision margins are based on consensus recommendations, and clear, evidence-based data to guide the surgeon in each case is limited. Mohs micrographic surgery (MMS) offers the surgeon the ability to assess 100% of the surgical margin, far better than margins evaluated with the standard bread-loaf sectioning technique. Immunohistochemical stains such as MART-1 allow for the reliable identification of melanoma in frozen sections and produce cure rates at least as good as standard excision with traditional margins.

*Both authors contributed equally to the manuscript.

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Campoli, M., Freeman, S., Brodland, D.G., Zitelli, J. (2012). Mohs Micrographic Surgery for the Treatment of Cutaneous Melanoma. In: Nouri, K. (eds) Mohs Micrographic Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-2152-7_18

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