A Pathway for the Regulation of Prostaglandins and Parturition

  • D. M. Olson
  • T. Zakar
  • Z. Smieja
  • E. A. MacLeod
  • S. L. Brown


Parturition is the culmination of dual physiological processes, both of which develop in parallel at the end of gestation (Fig. 10.1). They are the change in sensitivity or responsiveness that occurs with the target organs such as the myometrium, enabling it to respond to activators of contraction with coordinated, synchronous activity; and the generation of effector molecules which elicit the alterations of physiological state of the target organs. This chapter will deal with the second part of this process and will focus on the generation of prostaglandins, compounds which have been assigned a central role in eliciting the final events of parturition.


Prostaglandin Synthesis Fetal Membrane Human Amnion Human Parturition Decidual Stromal Cell 
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Copyright information

© Royal College of Obstetricians and Gynaecologists 1992

Authors and Affiliations

  • D. M. Olson
  • T. Zakar
  • Z. Smieja
  • E. A. MacLeod
  • S. L. Brown

There are no affiliations available

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