National Coordination of Molecular Genetic Services

  • A. P. Read


Virologists, pathologists, oncologists, immunologists and biochemists all use molecular genetic techniques as one of their investigative tools. Here, however, I shall restrict myself to molecular genetic investigations performed in a clinical genetics setting, but including tests for any clinical genetic purpose and not just antenatal diagnosis. These services are at present applicable only to diseases with a simple mendelian mode of inheritance.


Recombination Expense Neurofibromatosis Phenylketonuria 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    McKusick VA. Mendelian inheritance in man, 9th edn. Baltimore: Johns Hopkins, 1990.Google Scholar
  2. 2.
    Harris R, Elles R, Craufurd et al. Molecular genetics in the National Health Service in Britain. J Med Genet 1989; 26:219–25.PubMedCrossRefGoogle Scholar
  3. 3.
    Rona RJ, Swan AV, Beech R et al. Demand for DNA probe testing in three genetic centres in Britain (August 1986 to July 1987). J Med Genet 1989; 26:226–36.PubMedCrossRefGoogle Scholar
  4. 4.
    Landegren U, Kaiser R, Caskey CT, Hood L. DNA diagnostics — molecular techniques and automation. Science 1988; 242:229–37.PubMedCrossRefGoogle Scholar
  5. 5.
    Cooper DN, Schmidtke J. Diagnosis of genetic disease using recombinant DNA, 2nd edn. Hum Genet 1989; 83:307–34.Google Scholar
  6. 6.
    Brock DJH. A consortium approach to molecular genetic services. J Med Genet 1990; 27:8–13.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 1991

Authors and Affiliations

  • A. P. Read

There are no affiliations available

Personalised recommendations