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Enteric and Other Secondary Hyperoxalurias

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Oxalate Metabolism in Relation to Urinary Stone

Part of the book series: The Bloomsbury Series in Clinical Science ((BLOOMSBURY))

Abstract

It has been known for 25 years that nephrolithiasis occurs more commonly in patients with intestinal disease than in the general population (Deren et al. 1962; Gelzayd et al. 1968). The majority of stones in these patients are composed predominantly of calcium oxalate (Gelzayd et al. 1968), and a mechanism to explain this observation became apparent with the demonstration about 15 years ago that individuals with ileal disease or resection excrete increased amounts of oxalate in the urine (Dowling et al. 1971; Admirand et al. 1971; Smith et al. 1972). The aim of this paper is to review present knowledge about the cause, clinical significance and treatment of enteric hyperoxaluria (EHO). In the course of a resumé of pertinent aspects of oxalate metabolism, other types of secondary hyperoxaluria will be briefly mentioned.

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Authors
  1. D. S. Rampton
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  2. M. Sarner
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Editors and Affiliations

  1. St. Peter’s Hospitals, 24, Endell Street, WC2H 9AE, London, UK

    G. Alan Rose MA, MD, FRCP, FRCPath, FRSC (Consultant Chemical Pathologist) (Consultant Chemical Pathologist)

  2. Institute of Urology, London, St. Paul’s Hospital, 24, Endell Street, WC2H 9AE, London, UK

    G. Alan Rose MA, MD, FRCP, FRCPath, FRSC (Consultant Chemical Pathologist) (Consultant Chemical Pathologist)

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Rampton, D.S., Sarner, M. (1988). Enteric and Other Secondary Hyperoxalurias. In: Rose, G.A. (eds) Oxalate Metabolism in Relation to Urinary Stone. The Bloomsbury Series in Clinical Science. Springer, London. https://doi.org/10.1007/978-1-4471-1626-4_7

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  • DOI: https://doi.org/10.1007/978-1-4471-1626-4_7

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