Abstract
Primary hyperoxaluria is an uncommon autosomal recessive disorder. The clinical features consist of nephrocalcinosis, recurrent renal stone, and progressive renal insufficiency, followed by the systemic deposition of oxalate crystals (oxalosis) (Williams and Smith 1983). In children the severity of the disorder ranges from death from renal failure in infancy to asymptomatic cases. The original anatomical description by Lepoutre in 1925 was of an infant dying of renal failure. The condition was first diagnosed in life by Newns and Black in 1953 in a girl of 12.5 yr with nephrocalcinosis and recurrent calcium-oxalate urolithiasis.
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Barratt, T.M., von Sperling, V., Dillon, M.J., Rose, G.A., Trompeter, R.S. (1988). Primary Hyperoxaluria in Children. In: Rose, G.A. (eds) Oxalate Metabolism in Relation to Urinary Stone. The Bloomsbury Series in Clinical Science. Springer, London. https://doi.org/10.1007/978-1-4471-1626-4_6
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DOI: https://doi.org/10.1007/978-1-4471-1626-4_6
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