Aspiration Cytology in Urological Oncology—the Urologist’s Viewpoint

  • D. F. Paulson


Aspiration cytology is a diagnostic technique which should become a part of the armamentarium of every practising urologist. The contributors to this timely volume exhaustively address the topic of aspiration cytology in the diagnosis and staging of urological malignancy. Their chapters adequately document that aspiration cytology not only has a role in the diagnosis of the primary urological malignancies but also has a specific role in determining the extent of spread without resorting to open surgical exploration. The data presented herein and the data which have accumulated elsewhere indicate that aspiration cytology: (1) is highly reliable when there is an acceptably low incidence of false positive results, (2) has been proved as safe as open surgical biopsy and (3) has a reasonably high yield with few false negative results. It may be instructive to examine the three specific areas in which aspiration biopsy has proved most valuable to the urological surgeon: the confirmation of questionable renal mass lesions, the diagnosis of prostatic adenocarcinoma and the determination of the spread of metastatic disease.


Core Biopsy Aspiration Biopsy Fine Needle Aspiration Biopsy Needle Tract Abnormal Node 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Kristensen JK, Holm HH, Rasmussen SN, Barlebo H (1972) Ultrasonically guided percutaneous puncture of renal masses. Scand J Urol Nephrol 6:49–56PubMedCrossRefGoogle Scholar
  2. 2.
    Thornbury JR (1972) Needle aspirations of avascular renal lesions. Radiology 105:299–302PubMedGoogle Scholar
  3. 3.
    Thommesen P, Nielsen B (1975) The value of fine needle aspiration biopsy and intravenous pyelography in the diagnosis of renal masses. Fortschr Geb Rontgenstr Nuklearmed Erganzungsband 122:248–251CrossRefGoogle Scholar
  4. 4.
    Stewart BH, Pasalis JK (1976) Aspiration and cytology in the evaluation of renal mass lesions. Cleve Clin Q 43:1–6PubMedGoogle Scholar
  5. 5.
    Karp W, Eklund L (1979) Ultrasound, angiography and fine needle aspiration biopsy in diagnosis of renal neoplasms. Acta Radiol 20:649–659Google Scholar
  6. 6.
    Helm CW, Burwood RJ, Harrison NW, Melcher DH (1983) Aspiration cytology of solid renal tumours. Br J Urol 55:249–253PubMedCrossRefGoogle Scholar
  7. 7.
    Wehle MJ, Grabstald H (1986) Contraindications to needle aspiration of a solid renal mass: tumor dissemination by renal needle aspiration. J Urol 136:446–448PubMedGoogle Scholar
  8. 8.
    Gibbons RP, Bush WH, Burnett LL (1977) Needle tract seeding following aspiration of renal cell carcinoma. J Urol 118:865–867PubMedGoogle Scholar
  9. 9.
    McLoughlin MJ, Ho CS, Langer B, McHattie J, Tao LC (1978) Fine needle aspiration biopsy of malignant lesions in and around the pancreas. Cancer 41:2413–2419PubMedCrossRefGoogle Scholar
  10. 10.
    von Schreeb T, Arner O, Skovsted G (1976) Renal adenocarcinoma. Is there a risk of spreading tumor cells in diagnostic puncture? Scand J Urol Nephrol 1:270–276CrossRefGoogle Scholar
  11. 11.
    Engzell U, Jakobsson PA, Sigurdson A, Zajicek J (1971) Aspiration biopsy of metastatic carcinoma in lymph nodes of the neck. Acta Otolaryngol (Stockh) 72:138–147CrossRefGoogle Scholar
  12. 12.
    Engzell U, Esposti PL, Rubio C, Sigurdson A, Zajicek J (1971) Investigation on tumor spread in connection with aspiration biopsy. Acta Radiol (Stockh) 10:385–398Google Scholar
  13. 13.
    Sinner WN, Zajicek J (1976) Implantation metastases after percutaneous transthoracic needle aspiration biopsy. Acta Radiol [Diagn] (Stockh) 17:473–480Google Scholar
  14. 14.
    Chodak GW, Steinberg GD, Bibbo M, Wied G, Straus FS II, Vogelzang NJ, Schoenberg HW (1986) The role of transrectal aspiration biopsy in the diagnosis of prostatic cancer. J Urol 135:299–302PubMedGoogle Scholar
  15. 15.
    Carter HB, Riehle RA, Koizumi JH, Amberson J, Vaughan ED (1986) Fine needle aspiration of the abnormal prostate: a cytohistological correlation. J Urol 135:294–298PubMedGoogle Scholar
  16. 16.
    Ljung BM, Cherrie R, Kaufman JJ (1986) Fine needle aspiration biopsy of the prostate gland: a study of 103 cases with histological followup. J Urol 135:955–958PubMedGoogle Scholar
  17. 17.
    Bissada NK, Rountree GA, Sulieman JS (1977) Factors affecting accuracy and morbidity in transrectal biopsy of the prostate. Surg Gynecol Obstet 145:869–872PubMedGoogle Scholar
  18. 18.
    Esposti PL (1974) Aspiration biopsy cytology in the diagnosis and management of prostatic carcinoma. Thesis, Stockholm: Stahl & Accidens Tryck, p 46Google Scholar
  19. 19.
    Thompson PM, Talbot RW, Packham DA, Dulake C (1980) Transrectal biopsy of the prostate and bacteraemia. Br J Surg 67:127–128PubMedCrossRefGoogle Scholar
  20. 20.
    Thompson PM, Pryor JP, Williams JP, Eyers DE, Dulake C, Scully MF, Kakkar WW (1982) The problem of infection after prostatic biopsy: the case for the transperineal approach. Br J Urol 54:736–740PubMedCrossRefGoogle Scholar
  21. 21.
    Ruebush TK, McConville JH, Calia FM (1979) A double blind study of trimethoprim-sulfamethoxazole prophylaxis in patients having transrectal biopsy of the prostate. J Urol 122:492–494PubMedGoogle Scholar
  22. 22.
    Davison P, Malament M (1971) Urinary contamination as a result of transrectal biopsy of the prostate. J Urol 105:545PubMedGoogle Scholar
  23. 23.
    Wendel RG, Evans AT (1967) Complications of punch biopsy of the prostate gland. J Urol 97:122–126PubMedGoogle Scholar
  24. 24.
    Esposti PL, Elman A, Norlen H (1975) Complications of transrectal aspiration biopsy of the prostate. Scand J Urol Nephrol 9:208PubMedCrossRefGoogle Scholar
  25. 25.
    McNeal JE (1965) Morphogenesis of prostatic carcinoma. Cancer 18:1659PubMedCrossRefGoogle Scholar
  26. 26.
    Tannenbaum M (1975) Differential diagnosis in uropathology, carcinoma in situ of prostate gland. Urology 5:143–146PubMedCrossRefGoogle Scholar
  27. 27.
    Oyasu R, Bahnson RR, Nowels K, Garnett JE (1986) Cytological atypia in the prostate gland: frequency, distribution and possible relevance to carcinoma. J Urol 135:959–962PubMedGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1988

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  • D. F. Paulson

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