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Mediators in Acute Lung Injury: The Whole Body Inflammatory Response Hypothesis

  • S. Westaby
Part of the Current Concepts in Critical Care book series (CRITICAL CARE)

Abstract

A wide variety of extrapulmonary events such as major sepsis, burns, fat embolism, multiple trauma and pancreatitis may initiate an acute lung injury with the development of the adult respiratory distress syndrome (ARDS) (Anon. 1985). This same phenomenon, though usually in a much less severe form, has been observed in the controlled therapeutic situations of haemodialysis (Craddock et al. 1977), cardiopulmonary bypass (Westaby 1983) and nylon fibre leucapheresis (Nusbacher et al. 1978) where blood traverses a number of allegedly biocompatible foreign surfaces.

Keywords

Cardiopulmonary Bypass Acute Lung Injury Chronic Granulomatous Disease Adult Respiratory Distress Syndrome Human Neutrophil Elastase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • S. Westaby

There are no affiliations available

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