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Mediators in Acute Lung Injury: The Whole Body Inflammatory Response Hypothesis

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Shock and the Adult Respiratory Distress Syndrome

Part of the book series: Current Concepts in Critical Care ((CRITICAL CARE))

Abstract

A wide variety of extrapulmonary events such as major sepsis, burns, fat embolism, multiple trauma and pancreatitis may initiate an acute lung injury with the development of the adult respiratory distress syndrome (ARDS) (Anon. 1985). This same phenomenon, though usually in a much less severe form, has been observed in the controlled therapeutic situations of haemodialysis (Craddock et al. 1977), cardiopulmonary bypass (Westaby 1983) and nylon fibre leucapheresis (Nusbacher et al. 1978) where blood traverses a number of allegedly biocompatible foreign surfaces.

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Authors
  1. S. Westaby
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Editor information

Editors and Affiliations

  1. Department of Anaesthesia, Charing Cross and Westminster Medical School, Fulham Palace Road, London, W6 8RF, England

    Wolfgang Kox MD (Senior Lecturer, Honorary Consultant Anaesthetist (Director, Intensive Care Unit) (Senior Lecturer, Honorary Consultant Anaesthetist (Director, Intensive Care Unit)

  2. Charing Cross Hospital, Fulham Palace Road, London, W6 8RF, England

    Wolfgang Kox MD (Senior Lecturer, Honorary Consultant Anaesthetist (Director, Intensive Care Unit) (Senior Lecturer, Honorary Consultant Anaesthetist (Director, Intensive Care Unit)

  3. Department of Medicine, The Middlesex Hospital Medical School, Mortimer Street, London, W1P 7PN, England

    David Bihari MA, MRCP (Lecturer in Medicine) (Lecturer in Medicine)

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© 1988 Springer-Verlag Berlin Heidelberg

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Westaby, S. (1988). Mediators in Acute Lung Injury: The Whole Body Inflammatory Response Hypothesis. In: Kox, W., Bihari, D. (eds) Shock and the Adult Respiratory Distress Syndrome. Current Concepts in Critical Care. Springer, London. https://doi.org/10.1007/978-1-4471-1443-7_3

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  • DOI: https://doi.org/10.1007/978-1-4471-1443-7_3

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1445-1

  • Online ISBN: 978-1-4471-1443-7

  • eBook Packages: Springer Book Archive

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