Abstract
For many years the treatment of septic shock essentially concentrated on the restoration of systemic blood pressure. Metaraminol, mephentermine, noradrenaline, angiotensin and other vasoconstrictors were widely used with rather limited success. More recently, dopamine has become the agent of choice as a vasopressor in the management of circulatory shock. There are several reasons for this. In the first place it combines alpha- and beta-mimetic properties of various strengths according to the dose administered, so that the drug can easily be titrated according to the clinical status of the patient. Secondly, it induces tachyarrhythmias less frequently than other available catecholamines. Finally, it can selectively dilate renal and mesenteric vascular beds when low doses are used.
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© 1988 Springer-Verlag Berlin Heidelberg
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Vincent, J.L. (1988). Optimal use of Vasoactive Agents in Septic Shock. In: Kox, W., Bihari, D. (eds) Shock and the Adult Respiratory Distress Syndrome. Current Concepts in Critical Care. Springer, London. https://doi.org/10.1007/978-1-4471-1443-7_14
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DOI: https://doi.org/10.1007/978-1-4471-1443-7_14
Publisher Name: Springer, London
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