A number of hemophilic patients will develop a persistent synovitis with swelling of a joint, and this condition appears to be inflammatory rather than hemorrhagic. This represents a poorly understood clinical syndrome. The natural history of such swelling is variable in that it may persist for months or years, may progress rapidly into a classic hemophilic arthropathy, or at times may clear spontaneously. It may be difficult to differentiate synovitis from recurrent bleeding, and at times there seems to be a close relationship between them. These two conditions represent what König (1892) referred to as the second-stage of hemophilic arthropathy. Because of the clinical importance of this condition, it will be described in some detail in this chapter.
KeywordsSynovitis Arthropathy Hemarthrosis
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