A number of hemophilic patients will develop a persistent synovitis with swelling of a joint, and this condition appears to be inflammatory rather than hemorrhagic. This represents a poorly understood clinical syndrome. The natural history of such swelling is variable in that it may persist for months or years, may progress rapidly into a classic hemophilic arthropathy, or at times may clear spontaneously. It may be difficult to differentiate synovitis from recurrent bleeding, and at times there seems to be a close relationship between them. These two conditions represent what König (1892) referred to as the second-stage of hemophilic arthropathy. Because of the clinical importance of this condition, it will be described in some detail in this chapter.
KeywordsRecurrent Bleeding Severe Hemophilia Soft Tissue Change Hemophilic Patient Patellofemoral Compartment
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