The malignancies most likely to affect the jejunal mucosa are the lymphomas or lymphosarcomas or more rarely the adenocarcinomas. They are usually diagnosed radiologically or at laparotomy and only very rarely by jejunal mucosal biopsy. Most malignancies of the jejunum in Western countries are circumscribed masses located in the middle or lower jejunum, and therefore not in the site normally biopsied by peroral technique. This contrasts with the so-called ‘Mediterranean lymphomas’ or IPSID (immunoproliferative small intestinal diseases) which are often diffuse, usually affect the duodenum and Upper jejunum (but may also extend into the lower parts of the small intestine), and are therefore within reach of the endoscope or peroral jejunal biopsy technique. Again, limited information is available on the ultrastructural appearances of both types of lymphomas [11,19,20,21,22,23,24,38].


Multiple Sclerosis Plasma Cell Lamina Propria Jejunal Mucosa Giardia Lamblia 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • Margot Shiner
    • 1
    • 2
    • 3
  1. 1.Clinical Research CentreHarrow, MiddlesexUK
  2. 2.Central Middlesex HospitalLondonUK
  3. 3.Northwick Park HospitalHarrow, MiddlesexUK

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