Adverse Effects of the Examination

  • Holger Pettersson
  • Derek C. F. Harwood-Nash


The subarachnoid space is a complicated physiologic system, which in the healthy individual provides an appropriate biochemical environment for the CNS, and which also controls the hydrodynamics around the CNS. The CTMM means an introduction of a foreign substance into the subarachnoid space, with ensuing risk of side effects. These may be caused by the needle puncture with subsequent CSF leak or by biochemical reaction to the injected contrast medium.


Lumbar Puncture Subarachnoid Space Needle Puncture Water Soluble Contrast Medium Cervical Myelography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Almén T, Golman K (1979) Pharmacology and toxicology of some intrathecal contrast media. In: Sackett JF, Strother CM (eds) New techniques in myelography. Harper and Row, Hagerstown, pp 7–24Google Scholar
  2. Baker RA, Hillman BJ, McLennan JE, Strand RD, Kaufman SM (1978) Sequelae of Metrizamide myelography in 200 examinations. AJR 130: 499–502PubMedGoogle Scholar
  3. Barry JF, Harwood-Nash DC, Fitz CR, Byrd SE, Boldt DW (1977) Metrizamide in pediatric myelography. Radiology 124: 409–418PubMedGoogle Scholar
  4. Cronquist S, Brismar J (1977) Cervical myelography with Metrizamide. Acta Radiol [Suppl] (Stockh) 355: 110–120Google Scholar
  5. Fitz CR, Harwood-Nash DC, Barry JF, Byrd SE (1977) Pediatric myelography with Metrizamide. Acta Radiol [Suppl] (Stockh) 355: 182–192Google Scholar
  6. Gonsette RE (1977) Cervical myelography with Metrizamide by suboccipital puncture. Acta Radiol [Suppl] (Stockh) 355: 121–126Google Scholar
  7. Harwood-Nash DC, Fitz CR (1976) Neuroradiological techniques and indications in infancy and childhood. In: Kaufman HJ (ed) Progress in pediatric radiology, vol. 5. S. Karger, Basel, pp. 2–85Google Scholar
  8. Haughton VM, Ho KC, Larson SJ, Unger GF, Correa-Paz F (1977) Experimental production of arachnoiditis with water soluble myelographic media. Radiology 123: 681–685PubMedGoogle Scholar
  9. Norman D (1981) Metrizamide myelography. In: Moss AA, Goldberg HI (eds). Interventional radiologic techniques: Computed tomography and ultrasonography. University of California Printing Department, San Francisco, pp 141–146Google Scholar
  10. Pettersson H, Fitz CR, Harwood-Nash DC, Armstrong E, Chuang S (1982a) Adverse reactions to myelography with Metrizamide in infants, children and adolescents. I. General and CNS effects. Acta Radiol [Diagn] (Stockh), in pressGoogle Scholar
  11. Pettersson H, Fitz Cr, Harwood-Nash DC, Chuang S, Armstrong E (1982b). Adverse reactions to myelography with Metrizamide in infants, children and adolescents. II. Local damage caused by the needle puncture and Metrizamide injection. Acta Radiol [Diagn] (Stockh), in pressGoogle Scholar
  12. Potts DG, Gomez DG, Abbott GF (1977). Possible causes of complications of myelography with water soluble contrast medium. Acta Radiol [Suppl] (Stockh) 355: 390–402Google Scholar
  13. Skalpe IO (1977) Adverse effects of water soluble contrast media in myelography, cisternography and ventriculography. Acta Radiol [Suppl] (Stockh) 355: 359–370Google Scholar
  14. Sortland O, Hovind K (1977). Myelography with Metrizamide in children. Acta Radiol [Suppl] (Stockh) 355: 211–220Google Scholar
  15. Strand RD, Baker RA, Rosenbaum AE, Drayer BP (1977) Myelography with Metrizamide in infants and children. Acta Radiol [Suppl] (Stockh) 355: 171–181Google Scholar
  16. Tourtellotte WW, Haerer AF, Heller GL, Somers JE (1964) Post lumbar puncture headaches. Charles C. Thomas, Springfield, Ill.Google Scholar
  17. Tourtellotte WW, Henderson WG, Tucher RP, Gilland O, Walker JE, Kokman E (1972) A randomized, double blind clinical trial comparing the 22 versus the 26 gauge needle in the production of the post-lumbar puncture syndrome in normal individuals. Headache 12: 73–78PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Holger Pettersson
    • 1
    • 2
  • Derek C. F. Harwood-Nash
    • 1
    • 3
  1. 1.Department of RadiologyThe Hospital for Sick ChildrenTorontoCanada
  2. 2.University of LundSweden
  3. 3.University of TorontoCanada

Personalised recommendations