KORSAKOV, Sergei Sergeivich

1854–1900
  • Peter Beighton
  • Greta Beighton

Abstract

KORSAKOV psychosis comprises amnesia and confabulation, frequently in association with polyneuritis. The condition, which occurs principally in alcoholics, is the consequence of an autosomal recessive defect of thiamine metabolism, which becomes apparent when the dietary intake is deficient.

Keywords

Encephalitis Thiamine Pyrophosphate Alco Polyneuropathy 

References

  1. Blass JP, Gibson GE (1977) Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome New Engl J Med 297:1367–1370PubMedCrossRefGoogle Scholar
  2. Korsakoff SS (1887) Disturbance of psychic function in alcoholic paralysis and its relation to the disturbance of the psychic sphere in multiple neuritis of nonalcoholic origin. Vestnik Psichiatrii Vol IV/2Google Scholar
  3. Korsakoff SS (1889) Psychic disorder in conjunction with multiple neuritis (Psychosis Polyneuritica S Cerebropathia Psychica Toxaemica). Medizinskoje Obozrenije 31, No. 13Google Scholar
  4. Korsakoff SS (1890) Über eine besondere Form psychischer Störung kombiniert mit multipler Neuritis. Arch Psychiat Nervenkr 21Google Scholar
  5. Korsakoff SS (1891) Über Erinnerungsstörungen (Pseudoreminiszenzen) bei polyneuritischen Psychosen. Allg Z Psychiat 47Google Scholar
  6. Victor M, Adams RD, Collins GH (1971) The Wernicke-Korsakoff syndrome: a clinical and pathological study of 245 patients, 82 with post-mortem examinations. FA Davis, PhiladelphiaGoogle Scholar
  7. Victor M, Yakovlev PI (1955) SS Korsakoff s psychic disorder in conjunction with peripheral neuritis. A translation of Korsakoff s original article with brief comments on the author and his contribution to clinical medicine. Neurology (Minneap) 5: 394–406Google Scholar
  8. Wilks Sir S (1868) Alcoholic Paraplegia. Medical Times and Gazette 2: 467–472Google Scholar

Copyright information

© Springer-Verlag London Limited 1997

Authors and Affiliations

  • Peter Beighton
    • 1
  • Greta Beighton
    • 1
  1. 1.Department of Human GeneticsUniversity of Cape Town Medical SchoolSouth Africa

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