Solving the Inverse Problem in Radiotherapy Treatment Planning
A complex problem such as the optimisation of radiotherapy treatment requires the simultaneous solution of multiple objectives. Excluding the ideal case, where all the objectives can be solved uniquely, the objectives are in general conflicting in nature [3, 35, 80, 101, 119]. For example in radiotherapy one objective is to deliver a high dose to the PTA, and another one is to minimise the dose delivered to the OHT. Ideally 100% dose in the PTA is required to be achieved and 0% elsewhere, but due to the physical methods employed in the delivery of radiotherapy, it is not possible to simultaneously fulfil these two objectives. This is because in order to reach the diseased regions radiation is required to pass through healthy tissues.
KeywordsEntropy Attenuation Covariance Haas dPTA
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