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Quality of Life Assessment in Pancreatic Cancer

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Pancreatic Disease
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Abstract

Pancreatic cancer is well known to have a short duration of survival after diagnosis, and despite advances in treatment and therapies, little progress has been made regarding the outcome of prolonging quantity of life. Indeed, the majority of patients (80%) will receive palliative medical or surgical interventions aimed at control of symptoms only. Within this context of limited survival, quality of life assumes great importance. Clinicians should be concerned not only with advancing knowledge regarding the biophysical disease process but also with the consequences of illness on the well-being of their patients and how the patients cope with their illness, treatment and care. Such knowledge can only help to advance our understanding of pancreatic cancer.

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References

  1. Aaronson NK, Meyerowitz BE, Bard M et al. (1991) Quality of life research in oncology: past achievements and future priorities. Cancer 67:839–843.

    Article  PubMed  CAS  Google Scholar 

  2. Aaronson NK, Cull A, Kaasa S, Sprangers MA (1994) The European Organisation for Research and Treatment of Cancer (EORTC) modular approach to quality of life assessment in oncology: an update. In: Spilker B (ed) Quality of life and pharmacoeconomics in clinical trials, 2nd edn. Raven Press, New York.

    Google Scholar 

  3. Ahlgren JD (1996) Chemotherapy for pancreatic carcinoma. Cancer 78:654–663.

    PubMed  CAS  Google Scholar 

  4. Alter CL (1996) Palliative and supportive care of patients with pancreatic cancer. Semin Oncol 23:229–240.

    PubMed  CAS  Google Scholar 

  5. Andersen JS, Burris HA, Casper E et al. (1994) Development of a new system for assessing clinical benefit for patients with advanced pancreatic cancer. Proc Am Soc Clin Oncol 13:461 (abstract).

    Google Scholar 

  6. Bakkevold KE, Kambestad B (1995) Palliation of pancreatic cancer. A prospective multicentre study. Eur J Surg Oncol 21:176–182.

    PubMed  CAS  Google Scholar 

  7. Ballinger AB, McHugh M, Catnach SM, Alstead EM, Clark ML (1994) Symptom relief and quality of life after stenting for malignant bile duct obstruction. Gut 35:467–470.

    Article  PubMed  CAS  Google Scholar 

  8. Ballinger AB, McHugh M, Catnach SM et al. (1994) Symptom relief and quality of life after stenting for malignant bile duct obstruction. Gut 35:476–470.

    Article  Google Scholar 

  9. Bloechle C, Izbicki JR, Knoefel WT et al. (1995) Quality-of-life in chronic-pancreatitis — results after duodenum-preserving resection of the head of the pancreas. Pancreas 11:77–85.

    Article  PubMed  CAS  Google Scholar 

  10. Bowling A (1991) Measuring health: a review of quality of life measurement scales. Open University Press, Buckingham.

    Google Scholar 

  11. Bowling A (1991) Measuring disease. Open University Press, Buckingham.

    Google Scholar 

  12. Carter JP, Saxe GP, Newbold V, Peres CE, Campeau RJ, Bernal Green L (1993) Hypothesis: dietary management may improve survival from nutritionally linked cancers based on analysis of representative cases. J Am Coll Nutr 12:209–226.

    PubMed  CAS  Google Scholar 

  13. Carter DC (1995) Clinical features and management of carcinoma of the pancreas. Br J Hosp Med 54:459–464.

    PubMed  CAS  Google Scholar 

  14. Celia DF (1994) Quality of life: concepts and definitions. J Pain Symptom Management 9:186–192.

    Article  Google Scholar 

  15. De Wys WD (1986) Weightloss and nutritional abnormalities in cancer patients: incidence, severity and significance. In: Calman KC, Fearon KCH (eds) Nutritional support for the cancer patient. Bailliére Tindall, London.

    Google Scholar 

  16. Dunkel-Schatter C, Feinstein LG, Taylor SE, Falke RL (1991) Patterns of coping with cancer. Health Psychol 11:79–87.

    Article  Google Scholar 

  17. Ebert M, Friess H, Beger HG, Büchler M (1994) Role of octreotide in the treatment of pancreatic cancer. Digestion 55 (Suppl 1):48–51.

    Article  PubMed  Google Scholar 

  18. Fallowfield L (1990) Quality of life: the missing measurement in health care. Souvenir Press, London.

    Google Scholar 

  19. Faulkner A, Maguire P (1994) Talking to cancer patients and their families. Oxford Medical Publications, Oxford.

    Google Scholar 

  20. Fitzsimmons D (1998) Differences in perception of quality of life issues between health professionals and patients with pancreatic cancer. Psycho-Oncology (in press).

    Google Scholar 

  21. Gammon J (1991) Which way out of the crisis? Professional Nurse May:488–493.

    Google Scholar 

  22. Glaser BG and Strauss AL (1986) The discovery of grounded theory: strategies for qualitative research. Aldine, Chicago.

    Google Scholar 

  23. Glimelius B, Hoffman K, Graf W et al. (1995) Cost-effectiveness of palliative chemotherapy in advanced gastrointestinal cancer. Ann Oncol 6:267–274.

    PubMed  CAS  Google Scholar 

  24. Glimelius B, Hoffman K, Sjoden PO et al. (1996) Chemotherapy improves survival and quality-of-life in advanced pancreatic and biliary cancer. Ann Oncol 7:593–600.

    PubMed  CAS  Google Scholar 

  25. Hopkins A (1992) Measures of quality of life and the uses to which such measures may be put. Royal College of Physicians, London.

    Google Scholar 

  26. Ishikawa O, Ohigashi H, Nakaizumi A et al. (1993) Surgical resection of potentially curable pancreatic cancer with improved preservation of endocrine function: further evaluation of intraoperative cytodiagnosis. Hepatogastroenterology 40:443–447.

    PubMed  CAS  Google Scholar 

  27. Jaloweic A (1990) Issues in using multiple measures of quality of life. Semin Oncol Nursing 6:271–277.

    Article  Google Scholar 

  28. Karnofsky DA, Abelman WH, Craver LF et al. (1948) The use of nitrogen mustards in the palliative treatment of carcinoma. Cancer 1:634–656.

    Article  Google Scholar 

  29. Kawamata M, Ishitani K, Ishikawa K et al. (1996) Comparison between celiac plexus block and morphine treatment on quality of life in patients with pancreatic cancer pain. Pain 64:597–602.

    Article  PubMed  CAS  Google Scholar 

  30. Kelsen DP, Portenoy RK, Thaler HT (1995) Pain and depression in patients with newly diagnosed pancreas cancer. J Clin Oncol 13:748–755.

    PubMed  CAS  Google Scholar 

  31. Krech RL, Walsh D (1991) Symptoms of pancreatic cancer. J Pain Symptom Management 6:360–367.

    Article  CAS  Google Scholar 

  32. Lancet Editorial (1995) Quality of life and clinical trials. Lancet 346:1–2.

    Google Scholar 

  33. Lebovits AH and Lefkowitz M (1989) Pain management of pancreatic carcinoma: a review. Pain 36:1–11.

    Article  PubMed  CAS  Google Scholar 

  34. Lebovits AH, Lefkowitz M (1988) Pain management of pancreatic carcinoma: a review. Pain: 36,1–11.

    Article  Google Scholar 

  35. Lionetto R, Pugliese V, Bruzzi P and Rosso R (1995) No standard treatment is available for advanced pancreatic cancer. Eur J Cancer 31A:882–887.

    Article  PubMed  CAS  Google Scholar 

  36. Lionetto R, Pugliese V, Bruzzi P, Rosso R (1995) No standard treatment is available for advanced pancreatic cancer. Eur J Cancer 31A:882–887.

    Article  PubMed  CAS  Google Scholar 

  37. Luman W, Cull A, Palmer KR (1996) Quality of life following endoscopic stenting for malignant biliary obstruction. Abstract Presented at the British Society of Gastroenterology, Brighton, March, 1996.

    Google Scholar 

  38. Maguire (1992) Improving the recognition and treatment of affective disorders in cancer patients. In: Granville-Grasson K (ed) Recent advances in psychiatry 7. Churchill Livingstone, Edinburgh.

    Google Scholar 

  39. Maguire P (1985) Barriers to psychological care of the dying. BMJ 291:1711–1713.

    Article  PubMed  CAS  Google Scholar 

  40. McLaughlin S. (1994) Pancreatic cancer and diabetes. Diabetes Educ. 20, 20, 24, 26.

    Google Scholar 

  41. McLeod RS. Taylor BR. O’Connor BI et al. (1995) Quality of life, nutritional status, and gastrointestinal hormone profile following the Whipple procedure. Am J Surg 169:179–85

    Article  PubMed  CAS  Google Scholar 

  42. Moore H (1996) Activity of gemcitibine in patients with advanced pancreatic carcinoma. Cancer 78:633–638.

    PubMed  CAS  Google Scholar 

  43. Newman, I, McDowell C (1992) A guide to rating scales and questionnaires. Oxford University Press, Oxford.

    Google Scholar 

  44. Niezgoda HE, Pater JL (1993) A validation study of the domains of the core EORTC quality of life questionnaire. Qual Life Res 2:129–148.

    Article  Google Scholar 

  45. Ottery F (1996) Supportive nutritional management of the patient with pancreatic cancer. Oncology 10:26–32.

    PubMed  CAS  Google Scholar 

  46. Palmer KR, Kerr M, Knowles G, Cull A et al. (1994) Chemotherapy prolongs survival in inoperable pancreatic carcinoma. Br J Surg 81:882–885.

    Article  PubMed  CAS  Google Scholar 

  47. Passik SD and Breitbart WS (1996) Depression in patients with pancreatic carcinoma. Diagnostic and treatment issues. Cancer 78:615–626.

    PubMed  CAS  Google Scholar 

  48. Portenoy RK (1991) Pain and quality of life: clinical issues and implications for research. In: Tchelmedigion NS and Cella DF (eds) Quality of life in oncology: practice and research. New York.

    Google Scholar 

  49. Ringdal GI, Ringdal K (1993) Testing the EORTC quality of life questionnaire on cancer patients with heterogeneous diagnoses. Qual Life Res 2:129–140.

    Article  PubMed  CAS  Google Scholar 

  50. Schumate CR, Baron TH (1996) Palliative procedures for pancreatic cancer: when and which one? South Med J 89:27–32.

    Article  Google Scholar 

  51. Schoeman MN, Huibregtse K (1995) Pancreatic and ampullary carcinoma. [Review.] Gastro-intest Endosc Clin North Am 5(1):217–236.

    CAS  Google Scholar 

  52. Singh SM, Reber HA (1989) Surgical palliation for pancreatic cancer. Surg Clin North Am 69:599–611.

    PubMed  CAS  Google Scholar 

  53. Slevin ML (1992) Quality of life: philosophical question or clinical reality? Br Med J 305:466–469.

    Article  CAS  Google Scholar 

  54. Strauss A, Corbin J (1990) Basics of qualitative research: grounded theory procedures and techniques. Sage, New York.

    Google Scholar 

  55. Sugarbaker PH, Barosky I, Rosenberg SA, Gianola FJ (1982) Quality of life assessment of patients in extremity sarcoma clinical trials. Surgery 91:17–23.

    PubMed  CAS  Google Scholar 

  56. Tamura K, Kin S, Nagami H et al. (1992) Heterotopic autotransplantation of the distal pancreas segment after total pancreatectomy for cancer of the head of the pancreas. Pancreas 7:664–671.

    Article  PubMed  CAS  Google Scholar 

  57. Taylor OM, Benson EA, McMahon MJ. 1993. Clinical trial of tamoxifen in patients with irresectable pancreatic adenocarcinomavThe Yorkshire Gastrointestinal Tumour Group. Br J Surg 80:384–386.

    Article  PubMed  CAS  Google Scholar 

  58. Trede M, Carter DC (1987) Surgery of the pancreas. Churchill Livingstone, Edinburgh.

    Google Scholar 

  59. Watanapa P, Williamson RCN (1992) Surgical palliation for pancreatic cancer: developments during the past two decades. Br J Surg 79:8–20.

    Article  PubMed  CAS  Google Scholar 

  60. Webster S, Johnson CD (1994) Quality of life in pancreatic cancer. Fourth-year medical student study-in-depth project. University of Southampton (unpublished).

    Google Scholar 

  61. Yasue M, Sakamoto J, Morimoto T et al. (1995) Evaluation of the effect of pancreatic resection in advanced pancreatic cancer with special reference using hospital-free survival as a measure of quality of life. Jpn J Clin Oncol 25:37–45.

    PubMed  CAS  Google Scholar 

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© 1999 Springer-Verlag London Limited

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Fitzsimmons, D., Johnson, C.D. (1999). Quality of Life Assessment in Pancreatic Cancer. In: Johnson, C.D., Imrie, C.W. (eds) Pancreatic Disease. Springer, London. https://doi.org/10.1007/978-1-4471-0801-6_40

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  • DOI: https://doi.org/10.1007/978-1-4471-0801-6_40

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1205-1

  • Online ISBN: 978-1-4471-0801-6

  • eBook Packages: Springer Book Archive

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