Biochemical Markers of Fetoplacental Growth Restriction
During the last 20 years maternal serum biochemical screening for neural tube defects and trisomy-21 affected fetuses has become well established and widely practised in developed countries. More recently these maternal serum biochemical markers have been found to be associated with a diverse range of pregnancy complications other than aneuploidy . The single most common cause of intrauterine fetal growth restriction in developed (well-nourished) countries is preeclampsia, which is secondary to a defect in placentation and subsequent uteroplacental insufficiency. In this chapter we shall examine some of the evidence linking biochemical markers to fetoplacental growth restriction and its causes.
KeywordsObstet Gynecol Pregnancy Complication Maternal Serum Intrauterine Growth Restriction Preeclamptic Pregnancy
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