Abstract
In a normal human cell there are 46 chromosomes which, at appropriate stages of cell division (prophase and metaphase) can be observed as separate objects using high resolution light microscopy. Figure 18.1 shows chromosomes in a metaphase cell. The chromosomes have been stained to exhibit a series of bands along their lengths. Each chromosome also has a characteristic constriction called the centromere (indicated for some chromosomes in Figure 18.1a). Analysis of the appearance of chromosomes is routinely undertaken in hospital laboratories, for example, for diagnosis of inherited, or acquired, genetic abnormality or the monitoring of cancer treatment.
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Graham, J., Errington, P.A. (2000). Classification of Chromosomes: A Comparative Study of Neural Network and Statistical Approaches. In: Lisboa, P.J.G., Ifeachor, E.C., Szczepaniak, P.S. (eds) Artificial Neural Networks in Biomedicine. Perspectives in Neural Computing. Springer, London. https://doi.org/10.1007/978-1-4471-0487-2_19
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DOI: https://doi.org/10.1007/978-1-4471-0487-2_19
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