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Rare Histiotypes

  • E. M. Grossmann
  • R. A. Audisio
  • J. G. Geraghty
  • W. E. Longo

Abstract

Although the overwhelming majority of malignancies of the rectum are adenocarcinomas, a number of rare histiotypes will undoubtedly be encountered in clinical practice. Owing to their infrequent occurrence, one must be familiar with the tumor biology, natural history and treatment options for such lesions. These disease entities often present difficulties with diagnosis, staging, management, pathology and follow-up. In this chapter we will discuss the rare histiotypes most commonly encountered, including carcinoid tumors, rectal lymphoma, anorectal melanoma, neuroendocrine (NE) carcinoma of the rectum, vascular lesions, squamous cell carcinoma of the rectum and its variants, and, finally, rectal sarcoma. Although the ultimate management of such lesions may still be controversial in different physician’s eyes, often due to lack of experience with these tumors, we hope to provide an evidence-based approach to support decisions regarding appropriate therapy.

Keywords

Anal Canal Carcinoid Tumor Acquire Immune Deficiency Syndrome Wide Local Excision Adenosquamous Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Oberndorfer S. Karzinoide tumoren des dunndarms. Frankfurter Z Patol 1907;1:425–32.Google Scholar
  2. 2.
    Aranba G.V., Greenlee H.B. Surgical management of carcinoid tumors of the GI tract. Am Surg 1980;46:429–35.Google Scholar
  3. 3.
    Naunheim K.S., Zeitels J., Kaplan E.L., et al. Rectal carcinoid tumors-treatment and prognosis. Surgery 1983;94: 670–76.PubMedGoogle Scholar
  4. 4.
    Sauven P., Ridge J.A., Quan S.H., Sigurdson E.R. Anorectal carcinoid tumors: is aggressive surgery warranted? Ann Surg 1990;211:67–71.PubMedCrossRefGoogle Scholar
  5. 5.
    Jetmore A.B., Ray J.E., Gathright J.B., McMullen K.M., Hicks T.C., Timmcke A.E. Rectal carcinoids: the most frequent carcinoid tumor. Dis Colon Rectum 1992;35:717–25.PubMedCrossRefGoogle Scholar
  6. 6.
    Quan S.H., Bader G, Berg J.W. Carcinoid tumors of the rectum. Dis Colon Rectum 1964;7:197–206.PubMedCrossRefGoogle Scholar
  7. 7.
    Teleky B, Herbst F, Langle F, Neuhold N., Niederle B. The prognosis of rectal carcinoid tumours. Int J Colorectal Dis 1992;7:11–14.PubMedCrossRefGoogle Scholar
  8. 8.
    Burke M., Shepherd N., Mann C.V. Carcinoid tumors of the rectum and anus. Br J Surg 1987;74:358–61.PubMedCrossRefGoogle Scholar
  9. 9.
    Federspiel B.H., Burke A.P., Sobin L.H., Shekitka K.M. Rectal and colonic carcinoids: a clinicopathologic study of 84 cases. Cancer 1990;65:135–40.PubMedCrossRefGoogle Scholar
  10. 10.
    Soga J. Carcinoids of the rectum: an evaluation of 1271 reported cases. Jpn J Surg 1997;27:112–19.CrossRefGoogle Scholar
  11. 11.
    Koura A.N., Giacco G.G., Curley S.A., Skibber J.M., Feig B.W., Ellis L.M. Carcinoid tumors of the rectum: effect of size, histopathology, and surgical treatment on metastasis free survival. Cancer 1997;79:1294–98.PubMedCrossRefGoogle Scholar
  12. 12.
    Saclarides T.J., Szeluga D., Staren E.D. Neuroendocrine cancers of the colon and rectum: results of a ten-year experience. Dis Colon Rectum 1994;37:635–42.PubMedCrossRefGoogle Scholar
  13. 13.
    Mani S., Modlin I.M., Ballantyne G, Ahlman H, West B. Carcinoids of the rectum. J Am Coli Surg 1994;179:231–48.Google Scholar
  14. 14.
    Fitzgerald S.D., Meagher A.P., Moniz-Pereira P., Farrow G.M., Witzig T.E., Wolff B.G. Carcinoid tumor of the rectum: DNA ploidy is not a prognostic factor. Dis Colon Rectum 1996;39:643–48.PubMedCrossRefGoogle Scholar
  15. 15.
    Matsui K., Iwase T., Kitagawa M. Small, polypoid-appearing carcinoid tumors of the rectum: clinicopathologic study of 16 cases and effectiveness of endoscopic treatment. Am J GastroenteroL 1993;88:1949–53.PubMedGoogle Scholar
  16. 16.
    Schindl M., Niederle B., Hafner M., et al. Stage-dependent therapy of rectal carcinoid tumors. World J Surg 1998;22: 628–34.PubMedCrossRefGoogle Scholar
  17. 17.
    Soga J., Tazawa K. Pathologic analysis of carcinoids: histologic reevaluation of 62 cases. Cancer 1971;28:990–98.PubMedCrossRefGoogle Scholar
  18. 18.
    Yang K., Ulich T., Cheng L., Lewin K.J. The neuroendocrine products of intestinal carcinoids: an immunoperoxidase study of 35 carcinoid tumors stained for serotonin and eight polypeptide hormones. Cancer 1983;51:1918–26.PubMedCrossRefGoogle Scholar
  19. 19.
    Shirouzu K, Isomoto H., Kagegawa T., Morimatsu M. Treatment of rectal carcinoid tumors. Am J Surg 1990;160: 262–65.PubMedCrossRefGoogle Scholar
  20. 20.
    Ishikawa H., Imanishi K., Otani T., Okuda S., Tatsuta M., Ishiguro S. Effectiveness of endoscopic treatment of carcinoid tumors of the rectum. Endoscopy 1989;21:133–35.PubMedCrossRefGoogle Scholar
  21. 21.
    Higaki S., Nishiaki M., Mitani N., Yanai H, Tada M, Okita K. Effectiveness of local endoscopic resection of rectal carcinoid tumors. Endoscopy 1997;29:171–75.PubMedCrossRefGoogle Scholar
  22. 22.
    Inada-Shirankata Y., Sakai M, Kajiyama T, et al. Endoscopic resection of rectal carcinoid tumors using aspiration lumpectomy. Endsocopy 1996;28:34–38.Google Scholar
  23. 23.
    Herrmann R., Panahom A.M., Barcos M.P., Walsh D., Stutzman L. Gastrointestinal involvement in non-Hodgkin’s lymphoma. Cancer 1980;46:215–22.PubMedCrossRefGoogle Scholar
  24. 24.
    Heule B.V., Taylor C.R., Terry R., Lukes R.J. Presentation of malignant lymphoma in the rectum. Cancer 1982;49: 2602–607.CrossRefGoogle Scholar
  25. 25.
    Contreary K., Nance F.C., Becker W.F. Primary lymphoma of the gastrointestinal tract. Ann Surg 1980;191:593–98.PubMedCrossRefGoogle Scholar
  26. 26.
    Shepherd N.A., Hall P.A., Coates P.J., Levison D.A. Primary malignant lymphoma of the colon and rectum: a histopathological and immunohistochemical analysis of 45 cases with clinicopathological correlations. Histopathology 1988;12:235–52.PubMedCrossRefGoogle Scholar
  27. 27.
    Dawson I.M.P., Cornes J.S., Morson B.C. Primary malignant lymphoid tumours of the intestinal tract. Br J Surg 1961;49:80–89.PubMedCrossRefGoogle Scholar
  28. 28.
    Devine R.M., Beart R.W., Wolff B.G. Malignant lymphoma of the rectum. Dis Colon Rectum 1986;29:821–24.PubMedCrossRefGoogle Scholar
  29. 29.
    Aozasa K., Ohsawa M., Soma T., et al. Malignant lymphoma of the rectum. Jpn J Clin Oncol 1990;20:380–86.PubMedGoogle Scholar
  30. 30.
    Ohri S.K., Keane P.F., Sackier J.M., Hutton K, Wood C.B. Primary rectal lymphoma and malignant lymphomatous polyposis. Dis Colon Rectum 1989;32:1071–74.PubMedCrossRefGoogle Scholar
  31. 31.
    Keane P.F., Scott R., Wood C.B., Stewart I. Primary rectal lymphoma. Br J Clin Pract 1990;44:511–12.PubMedGoogle Scholar
  32. 32.
    Teare J.P., Greenfield S.M., Slater S. Rectal lymphoma after colectomy for ulcerative colitis. Gut 1992;33:138–39.PubMedCrossRefGoogle Scholar
  33. 33.
    Sibly T.F., Keane R.M., Lever J.V., Southwood W.F.W. Rectallymphoma in radiation injured bowel. Br J Surg 1985;72:879–80.PubMedCrossRefGoogle Scholar
  34. 34.
    Fan C.W., Chen J.S., Wang J.Y., Fan H.A. Perforated rectallymphoma in a renal transplant recipient: report of a case. Dis Colon Rectum 1997;40:1258–60.PubMedCrossRefGoogle Scholar
  35. 35.
    Gottlieb C.A., Meiri E., Maeda K.M. Rectal non-Hodgkin’s lymphoma: a clinicopathologic study and review. Henry Ford Hosp Med J 1990;38:255–58.PubMedGoogle Scholar
  36. 36.
    Burkes R.L., Meyer P.R., Gill P.S., Parker J.W., Rasheed S., Levine A.M. Rectal lymphoma in homosexual men. Arch Intern Med 1986;146:913–15.PubMedCrossRefGoogle Scholar
  37. 37.
    Lee M.H., Waxman M., Gillooley J.F. Primary malignant lymphoma of the anorectum in homosexual men. Dis Colon Rectum 1986;29:413–16.PubMedCrossRefGoogle Scholar
  38. 38.
    Levine A.M., Gill P.S., Meyer P.R., et al. Retrovirus and malignant lymphoma in homosexual men. JAMA 1985;254: 1921–25.PubMedCrossRefGoogle Scholar
  39. 39.
    Ziegler J.L., Beckstead J.A., Volberding P.A., et al. NonHodgkin’s lymphoma in 90 homosexual men. N Engl J Med 1984;311:565–70.PubMedCrossRefGoogle Scholar
  40. 40.
    Fleming I.D., Mitchell S., Dilawari R.A. The role of surgery in the management of gastric lymphoma. Cancer 1982;49: 1135–41.PubMedCrossRefGoogle Scholar
  41. 41.
    Freeman C, Berg J.W., Cutler S.J. Occurrence and prognosis of extranodallymphomas. Cancer 1972;29:252–60.PubMedCrossRefGoogle Scholar
  42. 42.
    Loehr W.I., Mujahed Z, Zahn D, Gray G.F., Thorbjarnarson B. Primary lymphoma of the gastrointestinal tract: a review of 100 cases. Ann Surg 1969;170:232–38.PubMedCrossRefGoogle Scholar
  43. 43.
    Shimono R, Mori M, Kido A, Adachi Y, Sugimachi K. Malignant lymphoma of the rectum treated preoperatively with hyperthermia and radiation. Eur I Surg Oncol 1995;21:83–84.CrossRefGoogle Scholar
  44. 44.
    Renard T.H., Morton R.L., Mathews R., Poulos E. Primary lymphoma of the rectum. Am Surg 1992;58:634–37.PubMedGoogle Scholar
  45. 45.
    Pais I.R., Garcia-Segovia I., RodrigueZ-Garcia I.L., Alvarez-Baleriola I., Garcia-Gonzalez M. Solitary plasmacytoma of the rectum: report of a case treated by endoscopic polypectomy and radiotherapy. Eur I Surg Oncol 1994;20: 592–94.Google Scholar
  46. 46.
    Price A, Quilty P.M., Ludgate S.M. Extramedullary plasmacytoma of the rectum: two cases treated by radiotherapy. Clin Radiol 1987;38:283–85.PubMedCrossRefGoogle Scholar
  47. 47.
    Sagar S, Selby P, Sloane I, McElwain T.I. Colorectal lymphoma simulating inflammatory colitis and diagnosed by immunohistochemistry. Postgrad Med J 1986;62: 51–53.PubMedCrossRefGoogle Scholar
  48. 48.
    Werdin C., Limas C., Knodell R.G. Primary malignant melanoma of the rectum: evidence for origination from rectal mucosal melanocytes. Cancer 1988;61:1364–70.PubMedCrossRefGoogle Scholar
  49. 49.
    Nicholson A.G., Cox P.M., Marks C.G., Cook M.G. Primary malignant melanoma of the rectum. Histopathology 1993;22:261–64.PubMedCrossRefGoogle Scholar
  50. 50.
    Alexander R.M., Cone L.A. Malignant melanoma of the rectal ampulla: report of a case and review of the literature. Dis Colon Rectum 1977;20:53–55.PubMedCrossRefGoogle Scholar
  51. 51.
    Slingluff C.L., Vollmer R.T., Seigler H.E. Anorectal melanoma: clinical characteristics and results of surgical management in twenty-four patients. Surgery 1990;107:1–9.PubMedGoogle Scholar
  52. 52.
    Goldman S., Glimelius B., Pahlman L. Anorectal malignant melanoma in Sweden: report of 49 patients. Dis Colon Rectum 1990;33:874–77.PubMedCrossRefGoogle Scholar
  53. 53.
    Weinstock M.A. Epidemiology and prognosis of anorectal melanoma. Gastroenterology 1993;104:174–78.PubMedGoogle Scholar
  54. 54.
    Pack G.T., Oropeza R. A comparative study of melanoma and epidermoid carcinoma of the anal canal: a review of 20 melanomas and 29 epidermoid carcinomas. Dis Colon Rectum 1967;10:161–76.PubMedCrossRefGoogle Scholar
  55. 55.
    Longo W.E., Vernava A.M., Wade T.P., Coplin M.A., Virgo K.S., Johnson F.E. Rare anal canal cancers in the US veteran: patterns of disease and results of treatment. Am Surg 1995;61:495–500.PubMedGoogle Scholar
  56. 56.
    Brady M.S., Kavolius J.P., Quan S.H.Q. Anorectal melanoma: a 64-year experience at Memorial Sloan-Kettering Cancer Center. Dis Colon Rectum 1995;38:146–51.PubMedCrossRefGoogle Scholar
  57. 57.
    Thibault C, Sangar P, Nivatvongs S, Ilstrup D.M., Wolff B.G. Anorectal melanoma: an incurable disease? Dis Colon Rectum 1997;40:661–68.PubMedCrossRefGoogle Scholar
  58. 58.
    Ben-Izhak O, Levy R, Weill S, et al. Anorectal malignant melanoma: a clinicopathologic study, including immunohistochemistry and DNA flow cytometry. Cancer 1997;79: 18–25.PubMedCrossRefGoogle Scholar
  59. 59.
    Wanebo H., Woodruff J.M., Farr G.H., Quan S.H. Anorectal melanoma. Cancer 1981;47:1891–900.PubMedCrossRefGoogle Scholar
  60. 60.
    Konstadoulakis M.M., Ricaniadis N, Walsh D, Karakousis C.P. Malignant melanoma of the anorectal region. J Surg Oncol 1995;58:118–20.PubMedCrossRefGoogle Scholar
  61. 61.
    Cooper P.H., Mills S.E., Allen M.S. Malignant melanoma of the anus: report of 12 patients and analysis of 255 additional cases. Dis Colon Rectum 1982;25:693–703.PubMedCrossRefGoogle Scholar
  62. 62.
    Ross M., Pezzi C., Pezzi T., Meurer D., Hickey R., Balch C. Patterns of failure in anorectal melanoma: a guide to surgical therapy. Arch Surg 1990;125:313–16.PubMedCrossRefGoogle Scholar
  63. 63.
    Freedman L.S. Malignant melanoma of the anorectal region: two cases of prolonged survival. Br J Surg 1984;71:164–65.PubMedCrossRefGoogle Scholar
  64. 64.
    Bolivar J.C., Harris I.W., Branch W., Sherman R.T. Melanoma of the anorectal region. Surg Gynecol Obstet 1982;154:337–41.PubMedGoogle Scholar
  65. 65.
    Ruscainai L., Petraglia S., Alotto M, Calvieri S, Vezzoni G. Postsurgical adjuvant therapy for melanoma: evaluation of a 3-year randomized trial with recombinant interferon-alpha after 3 and 5 years of follow up. Cancer 1997;70:2354–60.Google Scholar
  66. 66.
    Grob J.J., Dreno B., Salmoniere P., et al. Randomized trial of interferon-alpha-2a as adjuvant therapy in resected primary melanoma thicker than 1.5 mm without clinically detectable node metastasis. Lancet 1998;351:1905–10.PubMedCrossRefGoogle Scholar
  67. 67.
    Saclarides T.J., Szeluga D, Staren E.D. Neuroendocrine cancers of the colon and rectum. Dis Colon Rectum 1994;37:635–42.PubMedCrossRefGoogle Scholar
  68. 68.
    Schwartz A.M., Orenstein J.M. Small-cell undifferentiated carcinoma of the rectosigmoid colon. Arch Pathol Lab Med 1985;109:629–32.PubMedGoogle Scholar
  69. 69.
    Vortmeyer A.O., Lubensky I.A., Merino M.J., et al. Concordance of genetic alterations in poorly differentiated colorectal neuroendocrine carcinomas and associated adenocarcinomas. J. Natl Cancer Inst 1997;89:1448–53.PubMedCrossRefGoogle Scholar
  70. 70.
    Cox W.F., Pierce G.B. The endodermal origin of the endocrine cells of an adenocarcinoma of the colon of the rat. Cancer 1982;50: 1530–38.PubMedCrossRefGoogle Scholar
  71. 71.
    Sidhu G.S. The endodermal origin of digestive and respiratory tract APUD cells. Am J Pathol 1979;96:5–20.PubMedGoogle Scholar
  72. 72.
    Gaffy M.J., Mills S.E., Lack E.E. Neuroendocrine carcinoma of the colon and rectum. Am J Surg Pathol 1990;14:1010–23.CrossRefGoogle Scholar
  73. 73.
    Wick M.R., Wetherby R.P., Weiland L.H. Small cell neuroendocrine carcinoma of the colon and rectum: clinical, histologic, and ultrastructural study and immunohistochemical comparison with cloacogenic carcinoma. Hum Pathol 1987;18:9–21.PubMedCrossRefGoogle Scholar
  74. 74.
    Khansur T.K., Routh A., Mihas T.A., Underwood J.A., Smith G.F., Mihas A.A. Syndrome of inappropriate ADH secretion and diplopia: oat cell (small cell) rectal carcinoma metastatic to the central nervous system. Am J Gastroenterol 1995;90:1173–74.PubMedGoogle Scholar
  75. 75.
    Robidoux A., Monte M., Heppell J., Schurch W. Small-cell carcinoma of the rectum. Dis Colon Rectum 1984;28: 594–96.CrossRefGoogle Scholar
  76. 76.
    Shirouzu K., Morodomi T., Isomoto H., Yamauchi Y., Kakegawa T., Morimatsu M. Small-cell carcinoma of the rectum. Dis Colon Rectum 1985;28:434–39.PubMedCrossRefGoogle Scholar
  77. 77.
    Cunningham J.A., Garcia V.F., Uispe G. Diffuse cavernous rectal hemangioma-sphincter-sparing approach to therapy. Report of a case. Dis Colon Rectum 1989;32:344–47.PubMedCrossRefGoogle Scholar
  78. 78.
    Phillips B. Erectile tumor of the anus. Lond Med Gazette 1839;1:514–17.Google Scholar
  79. 79.
    Ghahremani G.G., Kangarloo H., Volberg F., Meyers M.A. Diffuse hemangioma of the colon in the Klippel-Trenaunay-Weber syndrome. Radiology 1976; 118:673–78.PubMedGoogle Scholar
  80. 80.
    Azizkhan R.G. Life-threatening hematochezia from a rectosigmoid vascular malformation in Klippel-Trenauray syndrome: long-term palliation using an argon laser. J Pediatr Surg 1991;26:1125–28.PubMedCrossRefGoogle Scholar
  81. 81.
    Demircan O, Sonmez H, Zeren S, Cosar E., Bicacki K., Ozkan S. Diffuse cavernous hemangioma of the rectum and sigmoid colon. Dig Surg 1998;15:713–15.PubMedCrossRefGoogle Scholar
  82. 82.
    Bland K.I., Abney H.T., MacGregor A.M.C., Hawkin I.F. Hemangiomatosis of the colon and anorectum: a case report and a review of the literature. Am Surg 1974;40: 626–35.PubMedGoogle Scholar
  83. 83.
    Coppa G.F., Eng K., Localio S.A. Surgical management of diffuse hemangioma of the colon, rectum and anus. Surg Gynecol Obstet 1984;159:17–22.PubMedGoogle Scholar
  84. 84.
    Djouhri H., Arrive L., Bouras T., Martin B., Monnier-Cholley L., Tubiana J.M. MR imaging of diffuse cavernous hemangioma of the rectosigmoid colon. AJR Am J Roentgenol 1998;171:413–17.PubMedGoogle Scholar
  85. 85.
    Ner Z., Altaca G. Diffuse cavernous rectal hemangioma: clinical appearance, diagnostic modalities and sphincter-saving approach to therapy-report of 2 and a collective review of 79 cases. Acta Chir Belg 1993;93:173–76.Google Scholar
  86. 86.
    Djouhri H., Arrive L., Bouras T., Martin B., Monnier-Cholley L., Tubiana J.M. Diffuse cavernous hemangioma of the rectosigmoid colon: imaging findings. J Comput Assist Tomogr 1998;22:851–55.PubMedCrossRefGoogle Scholar
  87. 87.
    Lupetin A.R. Diffuse cavernous hemangioma of the rectum: evaluation and MRI. Gastrointest Radiol 1990;15: 343–45.PubMedCrossRefGoogle Scholar
  88. 88.
    Hasegawa H., Teramoto T., Watanabe M. Diffuse cavernous hemangioma of the rectum: MR imaging with endorectal surface coil and sphincter-saving surgery. J Gastroenterol 1996;31:875–79.PubMedCrossRefGoogle Scholar
  89. 89.
    Tan R.C.F., Wang J.Y., Cheung Y.C., Wan W.Y.L. Diffuse cavernous hemangioma of the rectum complicated by invasion of the pelvic structures. Dis Colon Rectum 1998;41:1062–66.PubMedCrossRefGoogle Scholar
  90. 90.
    Katsinelos P., Eugenidis N., Paroutoglou G., Katsos J., Vasiliadis T. A case of diffuse cavernous hemangioma of the rectum with unusual clinical manifestations. Endoscopy 1995;27:405.PubMedCrossRefGoogle Scholar
  91. 91.
    Grasso G., Greco P., Tricoli D., Carullo F. Cavernous hemangioma of the colon and rectum: a case report. Tumori 1982;68:173–76.PubMedGoogle Scholar
  92. 92.
    Popovici A., Mitulescu G., Hortopan M., Jianu C, Iliescu C.A. Rectal hemangioma-a pseudo neoplastic form. A case report and review of the literature. Chirurgia (Bucur) 1998;93:261–65.Google Scholar
  93. 93.
    Jeffery P.J., Hawley P.R., Parks A.G. Colo-anal sleeve anastomosis in the treatment of diffuse cavernous hemangioma involving the rectum. Br J Surg 1976;63:678–82.PubMedCrossRefGoogle Scholar
  94. 94.
    Chisholm A.J., Hillkowitz P. Lymphangioma of the rectum. Am J Surg 1932;17:281.CrossRefGoogle Scholar
  95. 95.
    Kuramoto S., Sasaki S., Tsuda K, et al. Lymphangioma of the large intestine. Report of a case. Dis Colon Rectum 1998;31:900–905.CrossRefGoogle Scholar
  96. 96.
    Takano K., Suzuki N., Saito H, et al. A case of hemangiopericytoma in the pelvic retroperitoneum and review of the literature on hemangiopericytoma in the retroperitoneal space in Japan. Nippon Geka Gakkai Zasshi 1985;86:959–65.PubMedGoogle Scholar
  97. 97.
    Schneider T.A., Birkett D.H., Vernava A.M. Primary adenosquamous and squamous cell carcinoma of the colon and rectum. Int J Colorectal Dis 1992;7:144–47.PubMedCrossRefGoogle Scholar
  98. 98.
    Lafreniere R., Ketcham A.S. Primary squamous cell carcinoma of the rectum: report of a case and review of the literature. Dis Colon Rectum 1985;28:967–72.PubMedCrossRefGoogle Scholar
  99. 99.
    DiSario J.A., Randall W.B., Kendrick M.L., McWhorter W.P. Colorectal cancers of rare histologic types compared with adenocarcinomas. Dis Colon Rectum 1994;37:1277–80.PubMedCrossRefGoogle Scholar
  100. 100.
    Comer T.P., Beahrs O.H., Dockerty M.B. Primary squamous cell carcinoma of the colon and rectum. Cancer 1971;28: 1111–17.PubMedCrossRefGoogle Scholar
  101. 101.
    David V.C., Loring M. The relation of chronic inflammation and especially lymphogranuloma to the development of squamous cell carcinoma of the rectum. Ann Surg 1939; 109:837–43.PubMedCrossRefGoogle Scholar
  102. 102.
    Lorenzsonn V., Trier J.S. The fine structure of human rectal mucosa. Gastroenterology 1968;55:88–101.PubMedGoogle Scholar
  103. 103.
    Cabrera A., Pickren J.W. Squamous metaplasia and squamous-cell carcinoma of the rectosigmoid. Dis Colon Rectum 1967;10:288–97.PubMedCrossRefGoogle Scholar
  104. 104.
    Williams G.T., Blackshaw A.J., Morson B.C. Squamous carcinoma of the colorectum and its genesis. J Pathol 1979;129: 139–47.PubMedCrossRefGoogle Scholar
  105. 105.
    Cerezo L., Alvarez M., Edwards O., Price G. Adenosquamous carcinoma of the colon. Dis Colon Rectum 1985;28:597–603.PubMedCrossRefGoogle Scholar
  106. 106.
    Beradi R.S., Chen H.P., Lee S.S. Squamous cell carcinoma of the colon and rectum. Surg Gynecol Obstet 1986;163:493–96.Google Scholar
  107. 107.
    Vezeridis M.P., Herrera L.O., Lopez G.E., Ledesma E.J., Mittleman A. Squamous-cell carcinoma of the colon and rectum. Dis Colon Rectum 1983;26:188–91.PubMedCrossRefGoogle Scholar
  108. 108.
    Lafreniere R., Ketcham A.S. Squamous cell carcinoma of the rectum: a multimodality approach. J Surg Oncol 1986;32:106–109.PubMedCrossRefGoogle Scholar
  109. 109.
    Nigro N.D., Vaitkevicius V.K., Considine B. Combined therapy for cancer of the anal canal: a preliminary report. Dis Colon Rectum 1974;17:354–56.PubMedCrossRefGoogle Scholar
  110. 110.
    Nigro N.D., Vaitkevicius V.K., Buroker T., Bradley G.T., Considine B. Combined therapy for cancer of the anal canal. Dis Colon Rectum 1981;24:73–75.PubMedCrossRefGoogle Scholar
  111. 111.
    Pigott J.P., Williams G.B. Primary squamous cell carcinoma of the colorectum: case report and literature review of a rare clinical entity. J Surg Oncol 1987;35:117–19.PubMedCrossRefGoogle Scholar
  112. 112.
    Cagir B, Nagy M.W., Topham A., Rakinic J., Fry R.D. Adenosquamous carcinoma of the colon, rectum, and anus. Dis Colon Rectum 1999;42:258–63.PubMedCrossRefGoogle Scholar
  113. 113.
    Petrelli N.J., Valle A.A., Weber T.K., Rodriqurez-Bigas M. Adenosquamous carcinoma of the colon and rectum. Dis Colon Rectum 1996;39:1265–68.PubMedCrossRefGoogle Scholar
  114. 114.
    Cerezo L., Alvarez M., Edwards O., Price G. Adenosquamous carcinoma of the colon. Dis Colon Rectum 1985;28:597–603.PubMedCrossRefGoogle Scholar
  115. 115.
    Meijer S., Peretz T., Gaynor J.J., Tan C., Hajdu S.I., Brennan M.F. Primary colorectal sarcoma. Arch Surg 1990;125:1163–68.PubMedCrossRefGoogle Scholar
  116. 116.
    Feldtman R.W., Oram-Smith J.C., Teears R.J., Kircher T. Leiomyosarcoma of the rectum: the military experience. Dis Colon Rectum 1981;24:402–403.PubMedCrossRefGoogle Scholar
  117. 117.
    Khalifa A.A., Bong W.L., Rao V.K., Williams M.J. Leiomyosarcoma of the rectum: report of a case and review of the literature. Dis Colon Rectum 1986;29:427–32.PubMedCrossRefGoogle Scholar
  118. 118.
    Asbun J., Asbun H.J., Padilla A., Lang A., Bloch J. Leiomyosarcoma of the rectum. Am Surg 1992;58:311–14.PubMedGoogle Scholar
  119. 119.
    Haque S., Dean P.J. Stromal neoplasms of the rectum and anal canal. Hum Pathol 1992;23:762–67.PubMedCrossRefGoogle Scholar
  120. 120.
    Walsh T.H., Mann C.V. Smooth muscle neoplasms of the rectal and anal canal. Br J Surg 1984;71:597–99.PubMedCrossRefGoogle Scholar
  121. 121.
    Luna-Perez P., Rodriguez D.F., Lujan L., et al. Colorectal sarcoma: analysis of failure patterns. J Surg Oncol 1998;69: 36–40.PubMedCrossRefGoogle Scholar
  122. 122.
    Berridge D.C. Leimyosarcoma of the rectum: report of two cases illustrating an unusual presentation and the need for repeated biopsy. Dis Colon Rectum 1987;30:721–22.PubMedCrossRefGoogle Scholar
  123. 123.
    Randleman C.D., Wolff B.G., Dozois R.R., Spencer R.J., Weiland L.H., Ilstrup D.M. Leiomyosarcoma of the rectum and anus. Int J Colorect Dis 1989;4:91–96.CrossRefGoogle Scholar
  124. 124.
    Minsky B.D., Cohen A.M., Hajdu S.I., Nori D. Sphincter preservation in rectal sarcoma. Dis Colon Rectum 1990;33: 319–22.PubMedCrossRefGoogle Scholar
  125. 125.
    Lorenz H.P., Wilson W., Leigh B., Schecter W.P. Kaposi’s sacoma of the rectum in patients with the acquired immunodeficiency syndrome. Am J Surg 1990;160:681–83.PubMedCrossRefGoogle Scholar
  126. 126.
    Kaufmann T., Nisce L.Z., Coleman M. Case report: Kaposi’s sarcoma of the rectum-treatment with radiation therapy. Br J Radiol 1996;69:573–74.PubMedCrossRefGoogle Scholar
  127. 127.
    Endean E.D., Ross C.W., Strodel W.E. Kaposi’s sarcoma appearing as a rectal ulcer. Surgery 1987;101:767–69.PubMedGoogle Scholar

Copyright information

© Springer-Verlag London 2001

Authors and Affiliations

  • E. M. Grossmann
  • R. A. Audisio
  • J. G. Geraghty
  • W. E. Longo

There are no affiliations available

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