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Development; Normal Anatomy; Histology; Inflammatory Diseases

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Ear, Nose and Throat Histopathology

Abstract

The palatine tonsil is derived from the second pharyngeal pouch endoderm, which, like that of all the pharyngeal grooves, except the first, disappears early in development. A small recess, the tonsillar fossa, develops and the endodermal cells at its fundus proliferate. They are soon invaded by mesodermal cells and the closely associated cells of the two origins form the primordium of the palatine tonsil. A similar aggregation of mesodermal and endodermal cells is found on the first pharyngeal pouch, becoming the tubal tonsil, on the dorsum of the tongue, the lingual tonsil and on the dorsal pharyngeal wall, the adenoids. Thus the lymphoid/ epithelial conjunctions of Waldeyer’s ring are not specifically related to pharyngeal pouches alone, but surround the whole inlet of the foregut.

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References

  1. Regauer S, Gogg-Kamerer M, Braun H et al. Lateral neck cysts — the branchial theory revisited. A critical review and clinicopathological study of 97 cases with special emphasis on cytokeratin expression. APMIS 1997;105:623–630

    Article  PubMed  CAS  Google Scholar 

  2. von Gaudecker B. Development and functional anatomy of the human tonsilla palatina. Acta Otolaryngol 1988;454 (suppl):28–32

    Article  Google Scholar 

  3. Gebert A, Pabst R. M cells at locations outside the gut. Semin Immunol 1999;11:165–170

    Article  PubMed  CAS  Google Scholar 

  4. Andersson J, Abrams J, Björk L et al. Concomitant in vivo production of 19 different cytokines in human tonsils. Immunology 1994;83:16–24

    PubMed  CAS  Google Scholar 

  5. Brandtzaeg P. The B-cell development in tonsillar lymphoid follicles. Acta Otolaryngol (Stockh) 1996;523(suppl):55–59

    CAS  Google Scholar 

  6. Eggston AE, Wolff D. Histopathology of the ear, nose and throat. Williams and Wilkins, Baltimore, 1947

    Google Scholar 

  7. Padeh S, Brezniak N, Zemer D et al. Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. J Pediatr 1999;135:98–101

    Article  PubMed  CAS  Google Scholar 

  8. Osborn GR, Roydhouse N. The tonsillitis habit. WP Roydhouse, Auckland, New Zealand, 1976

    Google Scholar 

  9. Valles Fontanet J, Oliva Izquierdo T. Actinomycosis of the tonsils with a pseudotumoral presentation: a clinical case [In Spanish]. Acta Otorrhinolaringol Esp 1995;46:444–446

    CAS  Google Scholar 

  10. Buchanan G. Infectious mononucleosis. Ear Nose Throat J 1982;61:557–561

    Google Scholar 

  11. Wright DH, Isaacson PG. Biopsy pathology of the lymphoreticular system. Chapman and Hall, London, 1983

    Google Scholar 

  12. Prange E, Trautmann JC, Kreipe H et al. Detection of Epstein-Barr virus in lymphoid tissue of patients with infectious mononucleosis by in situ hybridization. J Pathol 1992;166:113–119.

    Article  PubMed  CAS  Google Scholar 

  13. Anagnostopoulos I, Hummel M, Kreschel C et al. Morphology, immunophenotype, and distribution of latently and/or productively Epstein-Barr virus-infected cells in acute infectious mononucleosis: implications for the interindividual infection route of Epstein-Barr virus. Blood 1995;85:744–750

    PubMed  CAS  Google Scholar 

  14. Isaacson PG, Schmid C, Pan L et al. Epstein-Barr virus latent membrane protein expression by Hodgkin and Reed— Sternberg-like cells in acute infectious mononucleosis. J Pathol 1992;167:267–271

    Article  PubMed  CAS  Google Scholar 

  15. Bozkurt T, Langer M, Fendel K et al. Granulomatous tonsillitis. A rare extraintestinal manifestation of Crohn’s disease. Dig Dis Sci 1992;37:1127–1130

    Article  PubMed  CAS  Google Scholar 

  16. Remaley AT, Rust S, Rosier M et al. Human ATP-binding cassette transporter (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred. Proc Natl Acad Sci USA 1999;96:12685–12690

    Article  PubMed  CAS  Google Scholar 

  17. Fredrickson DS. The inheritance of high density lipoprotein deficiency (Tangier disease). J Clin Invest 1964;43:228–236

    Article  PubMed  CAS  Google Scholar 

  18. Bale PM, Clifton-Bligh P, Benjamin BN et al. Pathology of Tangier disease. J Clin Pathol 1971;24:609–616

    Article  PubMed  CAS  Google Scholar 

  19. Wenig BM, Thompson LD, Frankel SS et al. Lymphoid changes of the nasopharyngeal and palatine tonsils that are indicative of human immunodeficiency virus infection. A clinicopathologic study of 12 cases. Am J Surg Pathol 1996;20:572–587

    Article  PubMed  CAS  Google Scholar 

  20. Chetty R, Batitang S. Kaposi’s sarcoma of the tonsil. ORL J Otorhinolaryngol Relat Spec 1998;60:48–50

    Article  PubMed  CAS  Google Scholar 

Download references

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© 2001 Springer-Verlag London

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Michaels, L., Hellquist, H.B. (2001). Development; Normal Anatomy; Histology; Inflammatory Diseases. In: Ear, Nose and Throat Histopathology. Springer, London. https://doi.org/10.1007/978-1-4471-0235-9_26

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  • DOI: https://doi.org/10.1007/978-1-4471-0235-9_26

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1128-3

  • Online ISBN: 978-1-4471-0235-9

  • eBook Packages: Springer Book Archive

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