Development; Normal Anatomy; Histology; Inflammatory Diseases

  • Leslie Michaels
  • Henrik B. Hellquist


The palatine tonsil is derived from the second pharyngeal pouch endoderm, which, like that of all the pharyngeal grooves, except the first, disappears early in development. A small recess, the tonsillar fossa, develops and the endodermal cells at its fundus proliferate. They are soon invaded by mesodermal cells and the closely associated cells of the two origins form the primordium of the palatine tonsil. A similar aggregation of mesodermal and endodermal cells is found on the first pharyngeal pouch, becoming the tubal tonsil, on the dorsum of the tongue, the lingual tonsil and on the dorsal pharyngeal wall, the adenoids. Thus the lymphoid/ epithelial conjunctions of Waldeyer’s ring are not specifically related to pharyngeal pouches alone, but surround the whole inlet of the foregut.


Latent Membrane Protein Lymphoid Follicle Infectious Mononucleosis Parapharyngeal Space Palatine Tonsil 
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Copyright information

© Springer-Verlag London 2001

Authors and Affiliations

  • Leslie Michaels
    • 1
    • 2
    • 3
  • Henrik B. Hellquist
    • 4
    • 5
  1. 1.Department of Histopathology, UCL Medical SchoolRockefeller BuildingLondonUK
  2. 2.Royal Free and UCL Medical SchoolUniversity of LondonUK
  3. 3.Royal National Throat, Nose nad Ear HospitalLondonUK
  4. 4.Department of Laboratory Medicine and PathologyHamad Medical CorporationDohaQatar
  5. 5.Haukeland University HospitalBergenNorway

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