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Neuroectodermal Tumours

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Abstract

Deposits of cerebral tissue are occasionally seen in the nose. If they are not in direct communication with the brain they are called gliomas. It must be stressed, however, that these lesions are not actually neoplasms of glial tissue, but rather heterotopic brain tissue.

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References

  1. Katz A, Lewis JS. Nasal gliomas. Arch Otolaryngol 1971;94:351–355

    Article  PubMed  CAS  Google Scholar 

  2. Perzin KH, Panyu H, Wechter S. Nonepithelial tumours of the nasal cavity, paranasal sinuses and nasopharynx. XII. Schwann cell tumours (neurilemmoma, neurofibroma, malignant Schwannoma). Cancer 1982;50:2193–2202

    Article  PubMed  CAS  Google Scholar 

  3. Hellquist HB, Lundgren J. Neurogenic sarcoma of the sinonasal tract. J Laryngol Otol 1991;105:186–190

    Article  PubMed  CAS  Google Scholar 

  4. Fernández PL, Cardesa A, Bombí JA et al. Malignant sinonasal epithelioid schwannoma. Virchows Arch (A) 1993;423:401–405.

    Article  Google Scholar 

  5. Gorsky M, Epstein JB. Melanoma arising from the mucosal surfaces of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;86:715–719

    Article  PubMed  CAS  Google Scholar 

  6. Holdcraft J, Gallagher JC. Malignant melanomas of the nasal and paranasal sinus mucosae. Ann Otol Rhinol Laryngol 1969;78:5–20

    PubMed  CAS  Google Scholar 

  7. Lewis MG, Martin JAM. Malignant melanoma of the nasal cavity in Ugandan Africans. Cancer 1967;20:1699–1705

    Article  PubMed  CAS  Google Scholar 

  8. Brandwein MS, Rothstein A, Lawson W et al. Sinonasal melanoma. A clinicopathologic study of 25 cases and literature meta-analysis. Arch Otolaryngol Head Neck Surg 1997;123:290–296

    Article  PubMed  CAS  Google Scholar 

  9. Regauer S, Anderhuber W, Richtig E et al. Primary mucosal melanomas of the nasal cavity and paranasal sinuses. A clinicopathological analysis of 14 cases. APMIS 1998; 106:403–410

    Article  PubMed  CAS  Google Scholar 

  10. Koppl H, Koppl R, Maier W et al. Recurrent, primary multifocal malignant melanoma of the mucous membrane of the upper respiratory tract. Peculiarities of the in-situcomponents [In German]. Pathologie 1999;20:195–199

    Article  CAS  Google Scholar 

  11. Hoorweg JJ, Loftus BM, Hilgers FJ. Osteoid and bone formation in a nasal mucosal melanoma and its metastasis. Histopathology 1997;31:465–468

    Article  PubMed  CAS  Google Scholar 

  12. Regauer S, Anderhuber W, Richtig E et al. Primary mucosal melanomas of the nasal cavity and paranasal sinuses. A clinicopathological analysis of 14 cases. APMIS 1998; 106:403–410

    Article  PubMed  CAS  Google Scholar 

  13. Brandwein MS, Rothstein A, Lawson W et al. Sinonasal melanoma. A clinicopathologic study of 25 cases and literature meta-analysis. Arch Otolaryngol Head Neck Surg 1999; 123:290–296

    Article  Google Scholar 

  14. Loree TR, Mullins AP, Spellman J et al. Head and neck mucosal melanoma: a 32-year review. Ear Nose Throat J 1999;78:372–375

    PubMed  CAS  Google Scholar 

  15. Mendeloff J. The olfactory neuroepithelial tumours. A review of the literature and report of six additional cases. Cancer 1957;10:944–956

    Article  PubMed  CAS  Google Scholar 

  16. Lewis JS, Hutter RVP, Tollefsen HR et al. Nasal tumours of olfactory origin. Arch Otolaryngol 1965;81:169–173

    Article  PubMed  CAS  Google Scholar 

  17. Oberman HA, Rice DH. Olfactory neuroblastoma. A clinicopathologic study. Cancer 1976;38:2494–2502

    Article  PubMed  CAS  Google Scholar 

  18. Silva EG, Butler JJ, Mackay B et al. Neuroblastomas and neuroendocrine carcinomas of the nasal cavity. A proposed new classification. Cancer 1982;50:2388–2405

    Article  PubMed  CAS  Google Scholar 

  19. Carney ME, O’Reilly RC, Sholevar B et al. Expression of the human Achaete-scute 1 gene in olfactory neuroblastoma (esthesioneuroblastoma). J Neurooncol 1995;26:35–43

    Article  PubMed  CAS  Google Scholar 

  20. Nelson RS, Perlman EJ, Askin FB. Is esthesioneuroblastoma a peripheral neuroectodermal tumour? Hum Pathol 1995;26:639–641

    Article  PubMed  CAS  Google Scholar 

  21. Argani P, Perez-Ordonez B, Xiao H et al. Olfactory neuroblastoma is not related to the Ewing family of tumours: absence of EWS/FLI1 gene fusion and MIC2 expression. Am J Surg Pathol 1998;22:391–398

    Article  PubMed  CAS  Google Scholar 

  22. Schwaab G, Lefebvre JL, Julerion M. Cystic adenoid carcinomas (cylindromas) and olfactory esthesio-neuromas of the nasal cavities and paranasal sinuses. Experience of the ORL Group of the National Federation of Cancer Centers [In French]. Neurochirurgie 1997;43:118–120

    PubMed  CAS  Google Scholar 

  23. Michaels L, Hyams VJ. Objectivity in the classification of tumours of the nasal epithelium. Postgrad Med J 1975;51:65–707

    Article  Google Scholar 

  24. Kairemo KJ, Jekunen AP, Kestila MS et al. Imaging of olfactory neuroblastoma — an analysis of 17 cases. Auris Nasus Larynx 1998;25:173–179

    Article  PubMed  CAS  Google Scholar 

  25. Pickuth D, Heywang-Kobrunner SH, Spielmann RP. Computed tomography and magnetic resonance imaging features of olfactory neuroblastoma: an analysis of 22 cases. Clin Otolaryngol 1999;24:457–461

    Article  PubMed  CAS  Google Scholar 

  26. Min KW. Usefulness of electron microscopy in the diagnosis of “small” round cell tumours of the sinonasal tract. Ultrastruct Pathol 1995;19:347–363

    Article  PubMed  CAS  Google Scholar 

  27. Silva EG, Butler JJ, Mackay B et al. Neuroblastomas and neuroendocrine carcinomas of the nasal cavity. A proposed new classification. Cancer 1982;50:2388–2405

    Article  PubMed  CAS  Google Scholar 

  28. Micheau C, Guerinot F, Bohoun C et al. Dopamine-Bhydroxylase and catecholamines in an olfactory esthesioneuroma. Cancer 1975;35:1309–1312

    Article  PubMed  CAS  Google Scholar 

  29. Harrison DFN. Surgical pathology of olfactory neuroblastoma. Head Neck Surg 1984;7:60–64

    Article  PubMed  CAS  Google Scholar 

  30. Argani P, Perez-Ordonez B, Xiao H et al. Olfactory neuroblastoma is not related to the Ewing family of tumours: absence of EWS/FLI1 gene fusion and MIC2 expression. Am J Surg Pathol 1998;22:391–398

    Article  PubMed  CAS  Google Scholar 

  31. Polin RS, Sheehan JP, Chenelle Munoz E et al. The role of preoperative adjuvant treatment in the management of esthesioneuroblastoma: the University of Virginia experience. Neurosurgery 1998;42:1029–1037

    Article  PubMed  CAS  Google Scholar 

  32. Gould VER, Linnoila I, Memoli VA et al. Neuroendocrine cells and neuroendocrine neoplasms of the lung. Lab Invest 1983;49:519–539

    PubMed  CAS  Google Scholar 

  33. Bonato M, Cerati M, Pagani A et al. Differential diagnostic patterns of lung neuroendocrine tumours. A clinico-pathological and immunohistochemical study of 22 cases. Virchows Arch (A) 1992;420:201–211

    Article  CAS  Google Scholar 

  34. Capella C, Heitz P, Höfler H et al. Revised classification of neuroendocrine tumours of the lung, pancreas and gut. Virchows Arch 1995;425:547–560

    Article  PubMed  CAS  Google Scholar 

  35. Böhm J, Koch S, Gais P et al. Prognostic value of MIB-1 in neuroendocrine tumours of the lung. J Pathol 1996; 178:402–429

    Article  PubMed  Google Scholar 

  36. Perez-Ordonez B, Caruana SM, Huvos AG et al. Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses. Hum Pathol 1998;29:826–832

    Article  PubMed  CAS  Google Scholar 

  37. Devaney K, Wenig BM, Abbondanzo SL. Olfactory neuroblastoma and other round cell lesions of the sinonasal region. Mod Pathol 1996;9:658–663

    PubMed  CAS  Google Scholar 

  38. Khoddami M, Squire J, Zielenska M et al. Melanotic neuroectodermal tumour of infancy: a molecular genetic study. Pediatr Dev Pathol 1998;1:295–299

    Article  PubMed  CAS  Google Scholar 

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© 2001 Springer-Verlag London

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Michaels, L., Hellquist, H.B. (2001). Neuroectodermal Tumours. In: Ear, Nose and Throat Histopathology. Springer, London. https://doi.org/10.1007/978-1-4471-0235-9_18

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  • DOI: https://doi.org/10.1007/978-1-4471-0235-9_18

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1128-3

  • Online ISBN: 978-1-4471-0235-9

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