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Immunology for Surgeons pp 398–405Cite as

Commentary on Chapter 19

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Abstract

Mucosal immunology is still poorly understood. Within gut-associated lymphoid tissues the mucosal barrier balances appropriate responsiveness to cognate antigen with physiological tolerance directed towards innocuous haptens and foreign peptides. Immune activity is controlled by the local cytokine microenvironment and by the production of large quantities of surface IgA (sIgA) designed to exclude antigen in the mucus layer.

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Authors
  1. Andrew P. Zbar
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  2. Anastasios J. Karayiannakis
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Editor information

Editors and Affiliations

  1. Kaplan Medical Center, PO Box 23273, King George PO Branch, 61231, Tel Aviv, Israel

    Andrew P. Zbar (Head of Colorectal Surgery,Senior Consultant Colorectal Surgeon) (Head of Colorectal Surgery,Senior Consultant Colorectal Surgeon)

  2. St James’s University Hospital, School of Medicine, Division of Surgery, University of Leeds, Clinical Sciences Building, Leeds, LS9 7TF, UK

    Pierre J. Guillou

  3. Department of Surgery, University of Alabama School of Medicine, Boshell Diabetes Building,1808 7th Avenue South, Birmingham, AL, 35233, USA

    Kirby I. Bland (Professor and Chairman Dept of Surgery) (Professor and Chairman Dept of Surgery)

  4. Oncology Unit 3rd Department Medicine, Athens Medical School Sotiria General Hospital, Athens, Greece

    Konstantinos N. Syrigos (Associate Professor of Medical Oncology, Head) (Associate Professor of Medical Oncology, Head)

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© 2002 Springer-Verlag London

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Zbar, A.P., Karayiannakis, A.J. (2002). Commentary on Chapter 19. In: Zbar, A.P., Guillou, P.J., Bland, K.I., Syrigos, K.N. (eds) Immunology for Surgeons. Springer, London. https://doi.org/10.1007/978-1-4471-0201-4_24

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  • DOI: https://doi.org/10.1007/978-1-4471-0201-4_24

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-85233-482-6

  • Online ISBN: 978-1-4471-0201-4

  • eBook Packages: Springer Book Archive

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