Dynamics of Cerebrospinal Fluid: From Theoretical Models to Clinical Applications

  • Marek CzosnykaEmail author
  • Zofia Czosnyka
  • Olivier Baledent
  • Ruwan Weerakkody
  • Magdalena Kasprowicz
  • Piotr Smielewski
  • John D. Pickard
Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)


Modeling of cerebrospinal fluid (CSF) circulation usually differs from models of brain tissue deformation. Hydrodynamics of CSF and its links with cerebral blood flow (CBF) are here of interest, as opposed to displacement of anatomical structures or distribution of stress-strain in the brain tissue in deformation modeling. In clinical­ practice, dynamics of the pressure may be easily monitored (although invasively, with directly placed pressure transducers) and dynamics of CSF flow and CBF can be imaged with phase-coded MRI (PCMRI; noninvasively). These two methods have an established clinical application in diagnosis and management of diseases associated with CSF circulatory dysfunctions, like hydrocephalus of various types, idiopathic intracranial hypertension, syringomieylia, etc.


Catheter Sine Triad Hydrocephalus Cough 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Financial support: European Community INTERREG grant (Amiens, Cambridge).


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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Marek Czosnyka
    • 1
    Email author
  • Zofia Czosnyka
    • 1
  • Olivier Baledent
    • 2
  • Ruwan Weerakkody
    • 1
  • Magdalena Kasprowicz
    • 3
  • Piotr Smielewski
    • 1
  • John D. Pickard
    • 1
  1. 1.Neurosurgical Unit, Department of Clinical NeurosciencesUniversity of CambridgeCambridgeUK
  2. 2.Department of Imaging and BiophysicsUniversity Hospital AmiensAmiens CedexFrance
  3. 3.Institute of Biomedical Engineering and InstrumentationWroclaw University of TechnologyWroclawPoland

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