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Lipid Mediators and Their Metabolism in the Brain pp 49–72Cite as

Recent Development on the Neurochemistry of Docosanoids

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Abstract

Neuroprotectins and resolvins are subfamilies of endogenous oxygenated metabolites derived from n-3 or ω-3 fatty acids (eicosapentaenoic acid, 20:5, EPA and docosahexaenoic acid, 22:6, DHA) (Serhan et al., 2000, 2002; Hong et al., 2003; Marcheselli et al., 2003). EPA not only modulates neuronal activity, but also participates in balancing the immune function by reducing arachidonic acid (20:4, ARA) level on cell membrane and prostaglandin E2 (PGE2) synthesis (Farooqui,2009).

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  1. Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, 43210, USA

    Akhlaq A. Farooqui

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Farooqui, A.A. (2011). Recent Development on the Neurochemistry of Docosanoids. In: Lipid Mediators and Their Metabolism in the Brain. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9940-5_2

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