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Lipid Mediators and Their Metabolism in the Brain pp 267–297Cite as

Cholesterol and Hydroxycholesterol in the Brain

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Abstract

The brain has higher concentration of cholesterol compared to other body parts (25% of the body’s free cholesterol) (Dietschy and Turley, 2004). In brain, cholesterol resides in two pools: one major pool associated with the myelin sheaths playing an important role in propagation of the electrical signals along the axons and the other minor pool associated with the plasma membranes of astrocytes and neurons (Dietschy and Turley, 2004).

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  1. Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, 43210, USA

    Akhlaq A. Farooqui

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Farooqui, A.A. (2011). Cholesterol and Hydroxycholesterol in the Brain. In: Lipid Mediators and Their Metabolism in the Brain. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9940-5_10

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