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In Vitro Performance Testing for Pulmonary Drug Delivery

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Controlled Pulmonary Drug Delivery

Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

This chapter provides a detailed review of in vitro testing methods for inhalation products. Specifically, the current compendial methods for pulmonary drug delivery are presented, discussion of cascade impactor use and simplification, determination of aerosol electrostatics, static characterization of particles and powders, solubility screening, and a review of research leading to improved dissolution studies for these products.

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Authors and Affiliations

  1. College of Pharmacy, University of Texas at Austin, Austin, TX, USA

    Jason T. McConville

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  1. Yoen-Ju Son
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  2. Jolyon P. Mitchell
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Correspondence to Jason T. McConville .

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  1. , Pharmaceutics Division - PHR 4.214, University of Texas, University Station 1, Austin, 78712, USA

    Hugh D.C. Smyth

  2. Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina, Chapel Hill, 27599, North Carolina, USA

    Anthony J. Hickey

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Son, YJ., Mitchell, J.P., McConville, J.T. (2011). In Vitro Performance Testing for Pulmonary Drug Delivery. In: Smyth, H., Hickey, A. (eds) Controlled Pulmonary Drug Delivery. Advances in Delivery Science and Technology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9745-6_17

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