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Colloidal Dynamics and Lipid Digestive Efficiency

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Abstract

The microstructure and physical properties of fat particles and their constituent stereochemical conformations at the oil–water interface are described along with the transit of lipolytic products through this interface. The physical and chemical aspects of the oral processing of emulsified and non-emulsified fats and oils are described. The gastric and intestinal processing of fat particles are described including the effects of emulsion structure, the formation of mixed micelles and the transit of fats, fat-derived particles and their products across the lumen, mucin layer and intestinal epithelium. The chapter concludes with a synopsis of possible methods for manipulating fat absorption and the potential of micelles as carrier systems for bioactive proteins and oligopeptides.

Matt Golding and Tinothy Wooster

Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand

Nestlé Research Center, Lausanne, Switzerland

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References

  • Abumrad N, Storch J (2006) Role of membrane and cytosolic fatty acid binding proteins in lipid processing by the small intestine. In: Johnson LR (ed) Physiology of the gastrointestinal tract. Academic Press, San Diego, pp 1693-1709

    Google Scholar 

  • Adams S, Singleton S, Juskaitis R, Wilson T (2007) In-vivo visualisation of mouth-material interactions by video rate endoscopy. Food Hydrocolloids 21:986-995

    Article  CAS  Google Scholar 

  • Akesson B, Gronowitz S, Herslöf B (1976) Stereospecificity of hepatic lipases. FEBS Lett 71:241-244

    Article  CAS  Google Scholar 

  • Armand M (2007) Lipases and lipolysis in the human digestive tract: Where do we stand? Curr Opin Clin Nutr Metabol Care 10:156-164

    Article  CAS  Google Scholar 

  • Armand M, Borel P, Dubois C, Senft M, Peyrot J, Salducci J, Lafont H, Lairon D (1993) Physicochemical properties of emulsions and lipolysis of dietary-fat in the human stomach. Gastroenterology 104:A608

    Google Scholar 

  • Armand M, Borel P, Dubois C, Senft M, Peyrot J, Salducci J, Lafont H, Lairon D (1994) Characterization of emulsions and lipolysis of dietary lipids in the human stomach. Am J Physiol 266:G372-381

    CAS  Google Scholar 

  • Armand M, Pasquier B, Andre M, Borel P, Senft M, Peyrot J, Salducci J, Portugal H, Jaussan V, Lairon D (1999) Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract. Am J Clin Nutr 70:1096-1106

    CAS  Google Scholar 

  • Bakker J, Mela DJ (1996) Effect of emulsion structure on flavor release and taste perception. In: McGorrin RJ, Leland JV (eds) Flavour-food interactions. ACS Publications, pp 36-47

    Google Scholar 

  • Bauer E, Jakob S, Mosenthin R (2005) Principles of physiology of lipid digestion. Asian-Australasian J Anim Sci 18:282-295

    CAS  Google Scholar 

  • Bellamy M, Godinot N, Mischler S, Martin N, Hartmann C (2009) Influence of emulsion composition on lubrication capacity and texture perception. Int J Food Sci Tech 44:1939-1949

    Article  CAS  Google Scholar 

  • Bendsen NT, Hother AL, Jensen SK, Lorenzen JK, Astrup A (2008) Effect of dairy calcium on fecal fat excretion: A randomized crossover trial. Int J Obes 32:1816-1824

    Article  CAS  Google Scholar 

  • Bernbäck S, Bläckberg L, Hernell O (1989) Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase. Biochim Biophys Acta 1001:286-293

    Article  Google Scholar 

  • Bernbäck S, Bläckberg L, Hernell O (1990) The complete digestion of human milk triacylglycerol in vitro requires gastric lipase, pancreatic colipase-dependent lipase, and bile salt-stimulated lipase. J Clin Invest 85:1221-1226

    Article  Google Scholar 

  • Bläckberg L, Hernell O, Bengtsson G, Olivecrona T (1979) Colipase enhances hydrolysis of dietary triglycerides in the absence of bile salts. J Clin Invest 64:1303-1308

    Article  Google Scholar 

  • Bonnaire L, Sandra S, Helgason T, Decker EA, Weiss J, McClements DJ (2008) Influence of lipid physical state on the in vitro digestibility of emulsified lipids. J Agric Food Chem 56:3791-3797

    Article  CAS  Google Scholar 

  • Borel P, Armand M, Ythier P, Dutot G, Melin C, Senft M, Lafont H, Lairon D (1994) Hydrolysis of emulsions with different triglycerides and droplet sizes by gastric lipase in vitro. Effect on pancreatic lipase activity. J Nutr Biochem 5:124-133

    Article  CAS  Google Scholar 

  • Borel P, Pasquier B, Armand M, Tyssandier V, Grolier P, Alexandre-Gouabau MC, Andre M, Senft M, Peyrot J, Jaussan V (2001) Processing of vitamin A and E in the human gastrointestinal tract. Am J Physiol 280:G95-103

    CAS  Google Scholar 

  • Carey MC, Small DM, Bliss CM (1983) Lipid digestion and absorption. Annu Rev Physiol 45:651-677

    Article  CAS  Google Scholar 

  • Carriere F, Laugier R, Barrowman JA, Douchet I, Priymenko N, Verger R (1993) Gastric and pancreatic lipase levels during a test meal in dogs. Scand J Gastroenterol 28:443-454

    Article  CAS  Google Scholar 

  • Chen HC (2001) Molecular mechanisms of sterol absorption. J Nutr 131:2603

    CAS  Google Scholar 

  • Chu BS, Rich GT, Ridout MJ, Faulks RM, Wickham MSJ, Wilde PJ (2009) Modulating pancreatic lipase activity with galactolipids: Effects of emulsion interfacial composition. Langmuir 25:9352-9360

    Article  CAS  Google Scholar 

  • Chu S, Montrose MH (1996) Non-ionic diffusion and carrier-mediated transport drive extracellullar pH regulation of mouse colonic crypts. J Physiol 494:783-793

    CAS  Google Scholar 

  • Dawson PA, Shneider BL, Hofmann AF (2006) Bile formation and the enterohepatic circulation. In: Johnson LR (ed) Physiology of the gastrointestinal tract. Academic Press, San Diego, pp 1437–1462

    Google Scholar 

  • de Bruijne DW, Bot A (1999) Fabricated fat-based foods. In: Rosenthal AJ (ed) Food texture: Measurement and perception. Aspen, Gaithersburg, pp 185-227

    Google Scholar 

  • de Bruijne DW, Hendrickx HACM, Alderliesten L, de Looff J (1993) Mouthfeel of foods. In: Dickinson E, Walstra P (eds) Food colloids and polymers: Stability and mechanical properties. Royal Society of Chemistry, Cambridge, pp 204-213

    Google Scholar 

  • Dickinson E (1996) Biopolymer interactions in emulsion systems: Influences on creaming, flocculation, and rheology. In: Parris N, Kato A, Creamer LK, Pearce J (eds) Macromolecular interactions in food technology ACS Publications, pp 197-209

    Google Scholar 

  • Donovan JM, Jackson AA, Carey MC (1993) Molecular species composition of inter-mixed micellar/vesicular bile salt concentrations in model bile: Dependence upon hydrophilic-hydrophobic balance. J Lipid Res 34:1131-1140

    CAS  Google Scholar 

  • Dresselhuis DM, De Hoog EHA, Cohen Stuart MA, Van Aken GA (2008a) Application of oral tissue in tribological measurements in an emulsion perception context. Food Hydrocolloids 22:323-335

    Article  CAS  Google Scholar 

  • Dresselhuis DM, De Hoog EHA, Cohen Stuart MA, Vingerhoeds MH, Van Aken GA (2008b) The occurrence of in-mouth coalescence of emulsion droplets in relation to perception of fat. Food Hydrocolloids 22:1170-1183

    Article  CAS  Google Scholar 

  • Dresselhuis DM, Stuart MAC, van Aken GA, Schipper RG, de Hoog EHA (2008c) Fat retention at the tongue and the role of saliva: Adhesion and spreading of ‘protein-poor’ versus ‘protein-rich’ emulsions. J Colloid Interface Sci 321:21-29

    Article  CAS  Google Scholar 

  • Erlanson-Albertsson C (1992) Pancreatic colipase. Structural and physiological aspects. Biochim Biophys Acta 1125:1-7

    CAS  Google Scholar 

  • Fahey D, Small DM (1986) Surface properties of 1,2-dipalmitoyl-3-acyl-sn-glycerols. Biochemistry 25:4468-4472

    Article  CAS  Google Scholar 

  • Fahey D, Small DM (1988) Phase behavior of monolayers of 1,2-dipalmitoyl-3-acyl-sn-glycerols. Langmuir 4:589-594

    Article  CAS  Google Scholar 

  • Foltz M, Maljaars J, Schuring EAH, van der Wal RJP, Boer T, Duchateau GSM, Peters HPF, Stellaard F, Masclee AA (2009) Intragastric layering of lipids delays lipid absorption and increases plasma CCK but has minor effects on gastric emptying and appetite. Am J Physiol 296:G982-991

    CAS  Google Scholar 

  • Gargouri Y, Julien R, Bois AG, Verger R, Sarda L (1983) Studies on the detergent inhibition of pancreatic lipase activity. J Lipid Res 24:1336-1342

    CAS  Google Scholar 

  • Glantz PO (1997) Interfacial phenomena in the oral cavity. Colloid Surf A Physicochem Eng Aspects 123:657-670

    Article  Google Scholar 

  • Golding M, Wooster TJ (2010) The influence of emulsion structure and stability on lipid digestion. Curr Opin Colloid Interface Sci 15:90-101

    Article  CAS  Google Scholar 

  • Gonnella PA, Neutra MR (1984) Membrane-bound and fluid-phase macromolecules enter separate prelysosomal compartments in absorptive cells of suckling rat ileum. J Cell Biol 99:909-917

    Article  CAS  Google Scholar 

  • Gueguen L, Pointillart A (2008) Digestive and metabolic interactions between lipids and calcium. Sciences des aliments 28:117-127

    Article  CAS  Google Scholar 

  • Gwynne RM, Thomas EA, Goh SM, Sjovall H, Bornstein JC (2004) Segmentation induced by intraluminal fatty acid in isolated guinea-pig duodenum and jejunum. J Physiol 556:557-569

    Article  CAS  Google Scholar 

  • Hamilton JA, Miller KW, Small DM (1983) Solubilization of triolein and cholesteryl oleate in egg phosphatidylcholine vesicles. J Biol Chem 258:12821-12826

    CAS  Google Scholar 

  • Hamilton JA, Small DM (1981) Solubilization and localization of triolein in phosphatidylcholine bilayers: A 13 C NMR study. Proc Natl Acad Sci USA 78:6878-6882

    Article  CAS  Google Scholar 

  • Hamosh M (1990) Lingual and gastric lipases. Nutrition 6:421-428

    CAS  Google Scholar 

  • Hansen GH, Niels-Christiansen LL, Immerdal L, Danielsen EM (2003) Scavenger receptor class B type I (SR-BI) in pig enterocytes: Trafficking from the brush border to lipid droplets during fat absorption. Gut 52:1424-1431

    Article  CAS  Google Scholar 

  • Hansen GH, Niels-Christiansen LL, Immerdal L, Nystrom BT, Danielsen EM (2007) Intestinal alkaline phosphatase: Selective endocytosis from the enterocyte brush border during fat absorption. Am J Physiol 293:G1325-1332

    CAS  Google Scholar 

  • Hansen GH, Rasmussen K, Niels-Christiansen LL, Danielsen EM (2009) Endocytic trafficking from the small intestinal brush border probed with FM dye. Am J Physiol 297:G708-715

    CAS  Google Scholar 

  • Hernell O, Staggers JE, Carey MC (1990) Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. Biochemistry 29:2041-2056

    Article  CAS  Google Scholar 

  • Hjelm RP, Thiyagarajan P, Schteingart C, Hofmann AF, Alkan-Onyuksel H, Ton-Nu H-T (1995) Structure of mixed micelles present in bile and intestinal contents based on studies of model systems. In: Hofmann AF, Paumgartner G, Stiehl A (eds) Bile acids in gastroenterology; basic and clinical advances. Kluwer Academic, Dordrecht, pp 41-58

    Google Scholar 

  • Hofmann AF (1999) Bile acids: The good, the bad, and the ugly. News Physiol Sci 14:24-29

    CAS  Google Scholar 

  • Hur SJ, Decker EA, McClements DJ (2009) Influence of initial emulsifier type on microstructural changes occurring in emulsified lipids during in vitro digestion. Food Chemistry 114:253-262

    Article  CAS  Google Scholar 

  • Hutchings JB, Lillford PJ (1988) The perception of food texture - the philosophy of the breakdown path. J Text Stud 19:103-115

    Article  Google Scholar 

  • Jørgensen J, Holtug K, Jeppesen PB, Mortensen PB (1998) Human rectal absorption of short-and medium-chain C2-C10 fatty acids. Scand J Gastroenterol 33:590-594

    Article  Google Scholar 

  • Kodali DR, Atkinson D, Small DH (1989) Molecular packing in triacyl-sn-glycerols: Influences of acyl chain length and unsaturation. J Disp Sci Techn 10:393-440

    Article  Google Scholar 

  • Kubow S (1996) The influence of positional distribution of fatty acids in native, interesterified and structure-specific lipids on lipoprotein metabolism and atherogenesis. J Nutr Biochem 7:530-541

    Article  CAS  Google Scholar 

  • Lentle RG, Janssen PWM, Goh K, Chambers P, Hulls C (2010) Quantification of the effects of the volume and viscosity of gastric contents on antral and fundic activity in the rat stomach maintained ex vivo. Dig Dis Sci DOI 10.1007/s10620-010-1164-y:1-12

    Google Scholar 

  • Lin HC, Zhao XT, Wang L (1996) Fat absorption is not complete by midgut but is dependent on load of fat. Am J Physiol 271:G62-67

    CAS  Google Scholar 

  • Lopez F, Samseth J, Mortensen K, Rosenqvist E, Rouch J (1996) Micro-and macrostructural studies of sodium deoxycholate micellar complexes in aqueous solutions. Langmuir 12:6188-6196

    Article  CAS  Google Scholar 

  • Lowe ME (1997) Structure and function of pancreatic lipase and colipase. Annu Rev Nutr 17:141-158

    Article  CAS  Google Scholar 

  • Lowe ME (2002) The triglyceride lipases of the pancreas. J Lipid Res 43:2007-2016

    Article  CAS  Google Scholar 

  • Macierzanka A, Sancho AI, Mills ENC, Rigby NM, Mackie AR (2009) Emulsification alters simulated gastrointestinal proteolysis of β-casein and β-lactoglobulin. Soft Matter 5:538-550

    Article  CAS  Google Scholar 

  • Madenci D, Egelhaaf SU (2010) Self-assembly in aqueous bile salt solutions. Curr Opin Colloid Interface Sci 15:109-115

    Article  CAS  Google Scholar 

  • Maldonado-Valderrama J, Gunning AP, Ridout MJ, Wilde PJ, Morris VJ (2009) The effect of physiological conditions on the surface structure of proteins: Setting the scene for human digestion of emulsions. Eur Phys J E 30:165-174

    Article  CAS  Google Scholar 

  • Maldonado-Valderrama J, Woodward NC, Gunning AP, Ridout MJ, Husband FA, Mackie AR, Morris VJ, Wilde PJ (2008) Interfacial characterization of β-lactoglobulin networks: Displacement by bile salts. Langmuir 24:6759-6767

    Article  CAS  Google Scholar 

  • Maljaars PWJ, van der Wal RJR, Haddeman EA, Peters HPF, Beindorff C, Masclee AAM (2008) Effect of droplet size of a fat emulsion delivered in the small intestine on satiety and food intake in healthy volunteers. Eur J Gastroenterol Hepatol 20:A54

    Google Scholar 

  • Malone ME, Appelqvist IAM, Norton IT (2003) Oral behaviour of food hydrocolloids and emulsions. Part 1. Lubrication and deposition considerations. Food Hydrocolloids 17:763-773

    Article  CAS  Google Scholar 

  • Marciani L, Gowland PA, Fillery-Travis A, Manoj P, Wright J, Smith A, Young P, Moore R, Spiller RC (2001) Assessment of antral grinding of a model solid meal with echo-planar imaging. Am J Physiol 280:G844-849

    CAS  Google Scholar 

  • Marciani L, Wickham M, Singh G, Bush D, Pick B, Cox E, Fillery-Travis A, Faulks R, Marsden C, Gowland PA (2007) Enhancement of intragastric acid stability of a fat emulsion meal delays gastric emptying and increases cholecystokinin release and gallbladder contraction. Am J Physiol 292:G1607-1613

    CAS  Google Scholar 

  • Marciani L, Wickham MSJ, Bush D, Faulks R, Wright J, Fillery-Travis AJ, Spiller RC, Gowland PA (2006) Magnetic resonance imaging of the behaviour of oil-in-water emulsions in the gastric lumen of man. Br J Nutr 95:331-339

    Article  CAS  Google Scholar 

  • McClements DJ, Decker EA, Park Y (2009) Controlling lipid bioavailability through physicochemical and structural approaches. Crit Rev Food Sci Nutr 49:48-67

    Article  Google Scholar 

  • McLauchlan G, Fullarton GM, Crean GP, McColl KE (1989) Comparison of gastric body and antral pH: A 24 hour ambulatory study in healthy volunteers. Br Med J 30:573-578

    CAS  Google Scholar 

  • Mel’nikov SM, Seijen ten Hoorn JWM, Eijkelenboom APAM (2004) Effect of phytosterols and phytostanols on the solubilization of cholesterol by dietary mixed micelles: An in vitro study. Chem Phys Lipids 127:121-141

    Article  CAS  Google Scholar 

  • Mela DJ, Langley KR, Martin A (1994) Sensory assessment of fat content: Effect of emulsion and subject characteristics. Appetite 22:67-81

    Article  CAS  Google Scholar 

  • Mu H, Høy CE (2004) The digestion of dietary triacylglycerols. Prog Lipid Res 43:105-133

    Article  CAS  Google Scholar 

  • Mun S, Decker EA, Park Y, Weiss J, McClements DJ (2006) Influence of interfacial composition on in vitro digestibility of emulsified lipids: Potential mechanism for chitosan’s ability to inhibit fat digestion. Food Biophysics 1:21-29

    Article  Google Scholar 

  • Norton I, Fryer P, Moore S (2006) Product/process integration in food manufacture: Engineering sustained health. AIChE J 52:1632-1640

    Article  CAS  Google Scholar 

  • Norton I, Moore S, Fryer P (2007) Understanding food structuring and breakdown: Engineering approaches to obesity. Obes Rev 8:83-88

    Article  Google Scholar 

  • Oelkers P, Kirby LC, Heubi JE, Dawson PA (1997) Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). J Clin Invest 99:1880-1887

    Article  CAS  Google Scholar 

  • Pafumi Y, Lairon D, de la Porte PL, Juhel C, Storch J, Hamosh M, Armand M (2002) Mechanisms of inhibition of triacylglycerol hydrolysis by human gastric lipase. J Biol Chem 277:28070-28079

    Article  CAS  Google Scholar 

  • Park GY, Mun S, Park Y, Rhee S, Decker EA, Weiss J, McClements DJ (2007) Influence of encapsulation of emulsified lipids with chitosan on their in vivo digestibility. Food Chemistry 104:761-767

    Article  CAS  Google Scholar 

  • Porter CJH, Trevaskis NL, Charman WN (2007) Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov 6:231-248

    Article  CAS  Google Scholar 

  • Redgrave TG, Kodali DR, Small DM (1988) The effect of triacyl-sn-glycerol structure on the metabolism of chylomicrons and triacylglycerol-rich emulsions in the rat. J Biol Chem 263:5118-5123

    CAS  Google Scholar 

  • Reis P, Miller R, Kragel J, Leser M, Fainerman VB, Watzke H, Holmberg K (2008a) Lipases at interfaces: Unique interfacial properties as globular proteins. Langmuir 24:6812-6819

    Article  CAS  Google Scholar 

  • Reis P, Miller R, Leser M, Watzke H, Fainerman VB, Holmberg K (2008b) Adsorption of polar lipids at the water- oil interface. Langmuir 24:5781-5786

    Article  CAS  Google Scholar 

  • Rossetti D, Yakubov GE, Stokes JR, Williamson AM, Fuller GG (2008) Interaction of human whole saliva and astringent dietary compounds investigated by interfacial shear rheology. Food Hydrocolloids 22:1068-1078

    Article  CAS  Google Scholar 

  • Salentinig S, Sagalowicz L, Glatter O (2010) Self-assembled structures and pKa value of oleic acid in systems of biological relevance. Langmuir 26:11670-11679

    Article  CAS  Google Scholar 

  • Sandra S, Decker EA, McClements DJ (2008) Effect of interfacial protein cross-linking on the in vitro digestibility of emulsified corn oil by pancreatic lipase. J Agric Food Chem 56:7488-7494

    Article  CAS  Google Scholar 

  • Sarkar A (2010) Behaviour of milk protein-stabilized oil-in-water emulsions in simulated physiological fluids. Riddet Institute. Massey university, Palmerston North

    Google Scholar 

  • Sarkar A, Goh KKT, Singh H (2009a) Colloidal stability and interactions of milk-protein-stabilized emulsions in an artificial saliva. Food Hydrocolloids 23:1270-1278

    Article  CAS  Google Scholar 

  • Sarkar A, Goh KKT, Singh RP, Singh H (2009b) Behaviour of an oil-in-water emulsion stabilized by [beta]-lactoglobulin in an in vitro gastric model. Food Hydrocolloids 23:1563-1569

    Article  CAS  Google Scholar 

  • Sarkar A, Horne DS, Singh H (2010) Pancreatin-induced coalescence of oil-in-water emulsions in an in vitro duodenal model. Int Dairy J 20:589-597

    Article  CAS  Google Scholar 

  • Schulze K (2006) Imaging and modelling of digestion in the stomach and the duodenum. Neurogastroenterol Mot 18:172-183

    Article  CAS  Google Scholar 

  • Schwizer W, Steingoetter A, Fox M (2006) Magnetic resonance imaging for the assessment of gastrointestinal function. Scand J Gastroenterol 41:1245-1260

    Article  Google Scholar 

  • Seimon RV, Wooster T, Otto B, Golding M, Day L, Little TJ, Horowitz M, Clifton PM, Feinle-Bisset C (2009) The droplet size of intraduodenal fat emulsions influences antropyloroduodenal motility, hormone release, and appetite in healthy males. Am J Clin Nutr 89:1729-1736

    Article  CAS  Google Scholar 

  • Silletti E, Vingerhoeds MH, Norde W, van Aken GA (2007) The role of electrostatics in saliva-induced emulsion flocculation. Food Hydrocolloids 21:596-606

    Article  CAS  Google Scholar 

  • Singh H, Ye A, Horne D (2009) Structuring food emulsions in the gastrointestinal tract to modify lipid digestion. Prog Lipid Res 48:92-100

    Article  CAS  Google Scholar 

  • Staggers JE, Hernell O, Stafford RJ, Carey MC (1990) Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings. Biochemistry 29:2028-2040

    Article  CAS  Google Scholar 

  • Stahl A (2004) A current review of fatty acid transport proteins (SLC27). Pflügers Arch 447:722-727

    Article  CAS  Google Scholar 

  • van Aken GA (2010) Relating food emulsion structure and composition to the way it is processed in the gastrointestinal tract and physiological responses: What are the opportunities? Food Biophysics DOI 10.1007/s11483-010-9160-5

    Google Scholar 

  • van Aken GA, Vingerhoeds MH, de Hoog EHA (2007) Food colloids under oral conditions. Curr Opin Colloid Interface Sci 12:251-262

    Article  CAS  Google Scholar 

  • Vingerhoeds MH, Blijdenstein TBJ, Zoet FD, van Aken GA (2005) Emulsion flocculation induced by saliva and mucin. Food Hydrocolloids 19:915-922

    Article  CAS  Google Scholar 

  • Vingerhoeds MH, Silletti E, de Groot J, Schipper RG, van Aken GA (2009) Relating the effect of saliva-induced emulsion flocculation on rheological properties and retention on the tongue surface with sensory perception. Food Hydrocolloids 23:773-785

    Article  CAS  Google Scholar 

  • Weinberg RB, Cook VR, DeLozier JA, Shelness GS (2000) Dynamic interfacial properties of human apolipoproteins A-IV and B-17 at the air/water and oil/water interface. J Lipid Res 41:1419-1427

    CAS  Google Scholar 

  • Wickham M, Garrood M, Leney J, Wilson PDG, Fillery-Travis A (1998) Modification of a phospholipid stabilized emulsion interface by bile salt: Effect on pancreatic lipase activity. J Lipid Res 39:623

    CAS  Google Scholar 

  • Wiedmann TS, Herrington H, Deye C, Kallick D (2001) Analysis of the diffusion of bile salt/phospholipid micelles in rat intestinal mucin. Chem Phys Lipids 112:81-92

    Article  CAS  Google Scholar 

  • Wilson FA, Sallee VL, Dietschy JM (1971) Unstirred water layers in intestine: Rate determinant of fatty acid absorption from micellar solutions. Science 174:1031-1033

    Article  CAS  Google Scholar 

  • Winkler FK, d’Arcy A, Hunziker W (1990) Structure of human pancreatic lipase. Nature 343:771-774

    Article  CAS  Google Scholar 

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Lentle, R.G., Janssen, P.W. (2011). Colloidal Dynamics and Lipid Digestive Efficiency. In: The Physical Processes of Digestion. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9449-3_5

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