Abstract
The microstructures and physical properties of proteins in muscle, plant and dairy products are described. The effects of food processing and the mechanics of denaturation of globular and fibrous proteins are examined. The physical and chemical aspects of enzymatic and microbial digestion of the various types of proteins in the stomach and small intestine and colon are detailed as well as the effects of antinutrients and Maillard reactions on their digestion.
Allan Hardacre
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
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References
Abderhalden E, Strauch FW (1911) Weitere studien über die wirkung der fermente des magensaftes. II. Mitteilung. Hoppe-Seyler´s Zeitschrift für physiologische Chemie 71:315-338
Ahmed AE, Smithard R, Ellis M (1991) Activities of enzymes of the pancreas, and the lumen and mucosa of the small intestine in growing broiler cockerels fed on tannin-containing diets. Br J Nutr 65:189-197
Asghar A, Henrickson RL (1982) Chemical, biochemical, functional, and nutritional characteristics of collagen in food systems. Adv Food Res 28:231-372
Aw TL, Swanson BG (1985) Influence of tannin on Phaseolus vulgaris protein digestibility and quality. J Food Sci 50:67-71
Bailey AJ, Restall DJ, Sims TJ, Duance VC (1979) Meat tenderness: Immunofluorescent localisation of the isomorphic forms of collagen in bovine muscles of varying texture. J Sci Food Agric 30:203-210
Baumstark R, Cohnheim O (1910) Über bindegewebsverdauung. Hoppe-Seyler´s Zeitschrift für physiologische Chemie 65:477-482
Baxter NJ, Lilley TH, Haslam E, Williamson MP (1997) Multiple interactions between polyphenols and a salivary proline-rich protein repeat result in complexation and precipitation. Biochemistry 36:5566-5577
Bendall JR, Restall DJ (1983) The cooking of single myofibres, small myofibre bundles and muscle strips from beef M. Psoas and M. Sternomandibularis muscles at varying heating rates and temperatures. Meat Science 8:93-117
Bender AE (1978) Food processing and nutrition. Academic Press, London
Bodwell C, Satterlee L, Hackler L (1980) Protein digestibility of the same protein preparations by human and rat assays and by in vitro enzymic digestion methods. Am J Clin Nutr 33:677-686
Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrère B (1997) Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci USA 94:14930-14935
Bourdillon J (1951) A crystalline bean seed protein in combination with phytic acid. J Biol Chem 189:65-72
Calbet JAL, Holst JJ (2004) Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans. Eur J Nutr 43:127-139
Carbonaro M, Grant G, Cappelloni M (2005) Heat-induced denaturation impairs digestibility of legume (Phaseolus vulgaris L and Vicia faba L) 7S and 11S globulins in the small intestine of rat. J Sci Food Agric 85:65-72
Carbonaro M, Grant G, Cappelloni M, Pusztai A (2000) Perspectives into factors limiting in vivo digestion of legume proteins: Antinutritional compounds or storage proteins? J Agric Food Chem 48:742-749
Chacko A, Cummings JH (1988) Nitrogen losses from the human small bowel: Obligatory losses and the effect of physical form of food. Gut 29:809-815
Charlton AJ, Baxter NJ, Khan ML, Moir AJG, Haslam E, Davies AP, Williamson MP (2002) Polyphenol/peptide binding and precipitation. J Agric Food Chem 50:1593-1601
Clark AH (1998) Gelation of globular proteins. In: Hill SE, Ledward DA, Mitchell JR (eds) Functional properties of food macromolecules. Aspen, Gaithersburg, pp 77-142
Dalgleish DG, Spagnuolo PA, Douglas Goff H (2004) A possible structure of the casein micelle based on high-resolution field-emission scanning electron microscopy. Int Dairy J 14:1025-1031
Damodaran S (2008) Amino acids, peptides and proteins. In: Damodaran S, Parkin KL, Fennema OR (eds) Fennema’s food chemistry. CRC Press, Boca Raton
Daniel H, Vohwinkel M, Rehner G (1990) Effect of casein and b-casomorphins on gastrointestinal motility in rats. J Nutr 120:252-257
El Jabri M, Abouelkaram S, Damez JL, Berge P (2010) Image analysis study of the perimysial connective network, and its relationship with tenderness and composition of bovine meat. J Food Eng 96:316-322
Etherington DJ (1977) The dissolution of insoluble bovine collagens by cathepsin BI, collagenolytic cathepsin and pepsin: The influence of collagen type, age and chemical purity on susceptibility. Connect Tissue Res 5:135-145
Etherington DJ (1984) The contribution of proteolytic enzymes to postmortem changes in muscle. J Anim Sci 59:1644-1650
Etherington DJ, Bailey AJ (1982) Metabolism of rat skin collagen: The effect of arrested development and subsequent catch-up growth on the stability of the connective tissue fibers. Coll Relat Res 2:507-522
Evenepoel P, Claus D, Geypens B, Hiele M, Geboes K, Rutgeerts P, Ghoos Y (1999) Amount and fate of egg protein escaping assimilation in the small intestine of humans. Am J Physiol 277:G935-943
Fox PF (2003) Milk proteins: General and historical aspects. In: Fox PF, P.L.H. M (eds) Advanced dairy chemistry: Proteins Part A. Kluwer, New York, pp 1-48
Friedman M (1996) Nutritional value of proteins from different food sources. A review. J Agric Food Chem 44:6-29
Gibson JA, Sladen GE, Dawson AM (1976) Protein absorption and ammonia production: The effects of dietary protein and removal of the colon. Br J Nutr 35:61-65
Gitler C (1964) Protein digestion and absorption in nonruminants. In: Munro HN, Allison JB (eds) Mammalian protein metabolism. Academic Press, New York, pp 35-69
Guyomarc’h F, Law AJR, Dalgleish DG (2003) Formation of soluble and micelle-bound protein aggregates in heated milk. J Agric Food Chem 51:4652-4660
Hagerman AE, Butler LG (1981) The specificity of proanthocyanidin-protein interactions. J Biol Chem 256:4494-4497
Harkness ML, Harkness RD, Venn MF (1978) Digestion of native collagen in the gut. Br Med J 19:240-243
Hughes R, Magee EAM, Bingham S (2000) Protein degradation in the large intestine: Relevance to colorectal cancer. Curr Issues Intest Microbiol 1:51-58
Hurrell RF, Carpenter KJ (1977) Nutritional significance of cross-link formation during food processing. Adv Exp Med Biol 86:225-238
Kauzmann W (1959) Some factors in the interpretation of protein denaturation. In: Anfinsen CB (ed) Adv protein chem. Academic press, New York, pp 1-64
Khattab RY, Arntfield SD, Nyachoti CM (2009) Nutritional quality of legume seeds as affected by some physical treatments, part 1: Protein quality evaluation. LWT-Food Sci Technol 42:1107-1112
Knuckles BE, Kuzmicky DD, Betschart AA (1985) Effect of phytate and partially hydrolyzed phytate on in vitro protein digestibility. J Food Sci 50:1080-1082
Kong F, Singh RP (2009) Digestion of raw and roasted almonds in simulated gastric environment. Food Biophys 4:365–377
Kratzer FH (1965) Soybean protein-mineral interrelationships. Fed Proc 24:1498-1500
Laakkonen E, Sherbon JW, Wellington GH (1970) Low-temperature, long-time heating of bovine muscle. 3. Collagenolytic activity. J Food Sci 35:181-184
Lacroix M, Bon C, Bos C, Leonil J, Benamouzig R, Luengo C, Fauquant J, Tome D, Gaudichon C (2008) Ultra high temperature treatment, but not pasteurization, affects the postprandial kinetics of milk proteins in humans. J Nutr 138:2342-2347
Ledl F, Schleicher E (1990) New aspects of the Maillard reaction in foods and in the human body. Angew Chem Int Ed Engl 29:565-594
Liener IE (1994) Implications of antinutritional components in soybean foods. Crit Rev Food Sci Nutr 34:31-67
Macfarlane GT, Allison C, Gibson SAW, Cummings JH (1988) Contribution of the microflora to proteolysis in the human large intestine. J Appl Microbiol 64:37-46
Macfarlane GT, Gibson GR, Beatty E, Cummings JH (1992) Estimation of short-chain fatty acid production from protein by human intestinal bacteria based on branched-chain fatty acid measurements. FEMS Microbiol Lett 101:81-88
Mahé S, Roos N, Benamouzig R, Davin L, Luengo C, Gagnon L, Gausserges N, Rautureau J, Tome D (1996) Gastrojejunal kinetics and the digestion of [15N]β-lactoglobulin and casein in humans: The influence of the nature and quantity of the protein. Am J Clin Nutr 63:546-552
Marcone MF (1999) Biochemical and biophysical properties of plant storage proteins: A current understanding with emphasis on 11S seed globulins. Food Res Int 32:79-92
Martens H, Stabursvik E, Martens M (1982) Texture and colour changes in meat during cooking related to thermal denaturation of muscle proteins. J Text Stud 13:291-309
Meisel H (1986) Chemical characterization and opioid activity of an exorphin isolated from in vivo digests of casein. FEBS Lett 196:223-227
Mohr V, Bendall JR (1969) Constitution and physical chemical properties of intramuscular connective tissue. Nature 223:404-405
Moughan PJ, Cranwell PD, Smith WC (1991) An evaluation with piglets of bovine milk, hydrolyzed bovine milk, and isolated soybean proteins included in infant milk formulas. II. Stomach-emptying rate and the postprandial change in gastric pH and milk-clotting enzyme activity. J Pediatr Gastroenterol Nutr 12:253-259
Offer G, Cousins T (1992) The mechanism of drip production: Formation of two compartments of extracellular space in muscle post mortem. J Sci Food Agric 58:107-116
Offer G, Knight P (1988) The structural basis of water-holding in meat. In: Lawrie RA (ed) Developments in meat science - 4. Elsevier, New York, pp 63–171
Okita TW, Rogers JC (1996) Compartmentation of proteins in the endomembrane system of plant cells. Annu Rev Plant Physiol Plant Mol Biol 47:327-350
Öste RE, Miller R, Sjöström H, Noren O (1987) Effect of Maillard reaction products on protein digestion. Studies on pure compounds. J Agric Food Chem 35:938-942
Öste RE, Sjödin P (1984) Effect of Maillard reaction products on protein digestion. In vivo studies on rats. J Nutr 114:2228-2234
Pinter KG, McLean A (1968) Correlation between weight, nitrogen, and fat content of stool. Am J Clin Nutr 21:1310-1313
Purslow PP (1985) The physical basis of meat texture: Observations on the fracture behaviour of cooked bovine M. Semitendinosus. Meat Science 12:39-60
Purslow PP (2002) The structure and functional significance of variations in the connective tissue within muscle. Comp Biochem Physiol A 133:947-966
Reddy IM, Kella NKD, Kinsella JE (1988) Structural and conformational basis of the resistance of β-lactoglobulin to peptic and chymotryptic digestion. J Agric Food Chem 36:737-741
Reuterswärd AL, Fabiansson S (1985) In vivo digestibility of insoluble collagen from bovine tendon as influenced by the inhibition of gastric acid secretion. J Food Sci 50:1523-1525
Sarkar A, Goh KKT, Singh RP, Singh H (2009) Behaviour of an oil-in-water emulsion stabilized by [beta]-lactoglobulin in an in vitro gastric model. Food Hydrocolloids 23:1563-1569
Shewry P, Napier J, Tatham A (1995) Seed storage proteins: Structures and biosynthesis. Plant Cell 7:945-956
Shewry PR (2003) Tuber storage proteins. Ann Bot 91:755-769
Sims TJ, Bailey AJ (1981) Connective tissue. In: Lawrie RA (ed) Developments in meat science - 2. Applied Science Publishers, London, pp 29-59
Stevens CE, Hume ID (1995) Comparative physiology of the vertebrate digestive system. Cambridge University Press, New York
Stipanuk MH (2006) Biochemical, physiological, & molecular aspects of human nutrition. Saunders-Elsevier, St. Louis
Strasburg G, Xiong YL, Chiang W (2008) Physiology and chemistry of edible muscle tissues. In: Damodaran S, Parkin KL, Fennema OR (eds) Fennema’s food chemistry. CRC Press, Boca Raton, pp 923-973
Tornberg E (2005) Effects of heat on meat proteins - implications on structure and quality of meat products. Meat Science 70:493-508
Tuohy KM, Hinton DJ, Davies SJ, Crabbe MJC, Gibson GR, Ames JM (2006) Metabolism of Maillard reaction products by the human gut microbiota - implications for health. Mol Nutr Food Res 50:847-857
Walstra P (1979) The voluminosity of bovine casein micelles and some of its implications. J Dairy Res 46:317-323
Weiss JB (1976) Enzymic degradation of collagen. Int Rev Connect Tissue Res 7:101-157
Zhang Q, Ames JM, Smith RD, Baynes JW, Metz TO (2009) A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: Probing the pathogenesis of chronic disease. J Proteome Res 8:754-769
Zioudrou C, Streaty R, Klee W (1979) Opioid peptides derived from food proteins. The exorphins. J Biol Chem 254:2446-2449
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Lentle, R.G., Janssen, P.W. (2011). Physical Aspects of the Digestion of Protein Particles. In: The Physical Processes of Digestion. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9449-3_4
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DOI: https://doi.org/10.1007/978-1-4419-9449-3_4
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