Advertisement

Ascorbate in the Carotid Body

  • Aneta Dymecka
  • Magdalena Marczak
  • Ahlam Ramadan
  • Piotr Suchocki
  • Mieczysław Pokorski
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 536)

Abstract

In previous work, we found that ascorbic acid (AA) or ascorbate is present in the carotid body of the cat (Pokorski and Gonet, 1997), the animal that, as opposed to man and other primates, is capable of synthesizing ascorbate (Chatterjee, 1973). The content of ascorbate is decreased in the hypoxic carotid body, which implies the compound might be involved in the chemosensing process, although the determinants of such an involvement remain unraveled.

Keywords

Electron Spin Resonance Electron Spin Resonance Signal Carotid Body Ascorbyl Palmitate Ascorbate Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Pokorski M, Gonet B. Hypoxia depletes ascorbate in the cat carotid body. Respir Physiol 107:213–218; 1997.PubMedCrossRefGoogle Scholar
  2. Chatterjee IB. Evolution and the biosynthesis of ascorbic acid. Science 182:1271–1272, 1973.PubMedCrossRefGoogle Scholar
  3. Pokorski M, Marczak M, Dymecka A, Suchocki P. Ascorbyl palmitate as a carrier of ascorbate into neural tissue. J BiomedSci 10:193–198; 2003.CrossRefGoogle Scholar
  4. Horning D. Distribution of ascorbic acid, metabolites and analogues in man and animals. Ann NY Acad Sci 258:103–118; 1975.CrossRefGoogle Scholar
  5. Ross D, Mendiratta S, Qu Z, Cobb CE, May JM. Ascorbate 6-palmitate protects human erythrocytes from oxidative damage.Free Rod Biol Med 26:81–89; 1999.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Aneta Dymecka
    • 1
  • Magdalena Marczak
    • 1
  • Ahlam Ramadan
    • 1
  • Piotr Suchocki
    • 2
  • Mieczysław Pokorski
    • 1
  1. 1.Department of Respiratory Research, Medical Research CenterPolish Academy of SciencesWarsaw
  2. 2.Department of Drug AnalysisWarsaw Medical UniversityWarsawPoland

Personalised recommendations