Abstract
Synaptic blockers are rather ineffective in blocking the carotid nerve discharge elicited by “natural” stimuli such as hypoxia, hypercapnia or acidity. At the same time, these drugs are quite effective in eliminating the effects produced by exogenous applications of excitatory transmitters. It is likely that the release of multiple transmitters by the natural stimuli prevents a single synaptic blocker from being effective. However, we propose an additional mechanism for this failure: electric coupling between carotid nerve terminals and glomus cells via gap junctions.
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Jiang, R.G., Eyzaguirre, C. (2003). Dye and Electric Coupling between Carotid Nerve Terminals and Glomus Cells. In: Pequignot, JM., Gonzalez, C., Nurse, C.A., Prabhakar, N.R., Dalmaz, Y. (eds) Chemoreception. Advances in Experimental Medicine and Biology, vol 536. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9280-2_32
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DOI: https://doi.org/10.1007/978-1-4419-9280-2_32
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