Honoring Pierre Dejours : His Contribution to the Study of the Role of the Arterial Chemoreceptors in the Regulation of Breathing in Humans

  • Henry Gautier
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 536)


In the mid-fifties, Dejours became interested in the contribution of the arterial chemoreceptors in the regulation of breathing in humans. The role, but not the intimate mechanisms, of the receptors was relatively well known thanks to the experiments of recording of afferent activity and of electrical stimulation or denervation of afferent nerves but, for obvious reasons, these experiments could not be performed in humans. Human beings are provided with the same chemosensitive structures as laboratory animals and the fact that functional responses to respiratory stimuli (hypoxia and/or hypercapnia) are about the same in humans and experimental animals makes it likely that in human beings, the part played by the reflexogenic drive is the same as in animals.


Carotid Body Ventilatory Response Oxygen Inhalation Peripheral Chemoreceptor Hyperoxic Exposure 
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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Henry Gautier
    • 1
  1. 1.Atelier de Physiologie RespiratoireFaculté de Médecine Saint-AntoineParisFrance

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