Abstract
With recent developments in cardiovascular technology, the outcomes of conventional therapies, such as percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, or left ventricular (LV) repair have markedly improved. However, these therapies have distinct limitations, especially in patients with severe ischemic and dilated cardiomyopathy. To overcome these obstacles, regenerative medicine, a new therapeutic approach using knowledge from cellular and molecular biology, has emerged in the past several years. These approaches include gene therapy, administration of growth factors, and use of bioengineered instrumentation. Among clinical and experimental trials, this chapter reviews the most recent findings in cell transplantation for the treatment of cardiomyopathy. In addition, we present our latest experimental results on the use of cardiomyocytes and skeletal myoblasts, which appear promising for future clinical applications.
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© 2003 Springer Science+Business Media New York
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Tambara, K. et al. (2003). Transplanting Cells for the Treatment of Cardiomyopathy. In: Matsumori, A. (eds) Cardiomyopathies and Heart Failure. Developments in Cardiovascular Medicine, vol 248. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9264-2_36
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DOI: https://doi.org/10.1007/978-1-4419-9264-2_36
Publisher Name: Springer, Boston, MA
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