Abstract
All that is currently known about the molecular genetics of the long QT syndrome (LQTS) has been discovered in the last 10 years. These discoveries have introduced the possibility of successful treatment of the syndrome based upon the patient's specific disease genotype. The purpose of this article is to review the deficiencies of β-blocker therapy in LQTS, illustrate the principal and potential efficacy of gene and mutation-specific therapy and explore the relevance of common LQT gene variants.
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Mason, J.W. (2003). Gene-Based Therapy of Long QT Syndrome. In: Matsumori, A. (eds) Cardiomyopathies and Heart Failure. Developments in Cardiovascular Medicine, vol 248. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9264-2_32
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DOI: https://doi.org/10.1007/978-1-4419-9264-2_32
Publisher Name: Springer, Boston, MA
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