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Hemodynamic Events Associated with Acute Focal Brain Ischemia and Reperfusion. Ischemic Penumbra

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Brain Ischemia

Abstract

Many studies have shown that the extent of injury caused by acute focal brain ischemia are determined by the severity and the duration of decreased cerebral blood flow (CBF).

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References

  1. Arnes, A., Wright., R., Kowada., M., et al., 1968, Amer J Pathol. 52: 437–453.

    Google Scholar 

  2. Andrews, R. J., 1991, Strake. 22: 943–949.

    Article  CAS  Google Scholar 

  3. Asplund, K., 1992, Cerebravase Dis. 2: 317–319.

    Article  Google Scholar 

  4. Astrup, J., Siesjo, B. K., Symon, L., 1981, Stroke. 12: 723–725.

    Article  PubMed  CAS  Google Scholar 

  5. Astrup, J., Symon, L., Branston, N. M., et al., 1977, Stroke. 8: 51–57.

    Article  PubMed  CAS  Google Scholar 

  6. Baird, A. E., Benfield, A., Schlaug, G., et al., 1997, Ann Neural. 41: 581–589.

    Article  CAS  Google Scholar 

  7. Baron, J. C., van Hummer, R., del Zoppo, G. J., 1995, Stroke. 26: 2219–2221.

    Article  PubMed  CAS  Google Scholar 

  8. Baron, J. C., Frackowiak, R. S. J., Herholi, K., et al., 1989, J Cerebr Blood Flow Metab. 9: 723–742.

    Article  CAS  Google Scholar 

  9. Bogolepov, N. N., Burd, G. S., 1981, Abst VII All-Union Symp. of Neurologists and Psychiatrists. Moscow. 2: 32–35 (in Russian).

    Google Scholar 

  10. Butcher, S. P., Bullock, R., Graham, D. I., et al., 1990, Stroke. 21: 1727–1733.

    Article  PubMed  CAS  Google Scholar 

  11. Chiamulera, C., Terron, A., Reggiani, A., et al., 1993, Brain Res. 606(2): 251–258.

    Article  PubMed  CAS  Google Scholar 

  12. Dereski, M.O., Chopp, M., Knight, R. A., et al., 1993, Acta Neuropathol. 85: 327–333.

    Article  PubMed  CAS  Google Scholar 

  13. Fisher, M., Takano, K., 1995, In Ballierie’s Clinical Neurology, Cerebrovascular Disease (Hachinski, V., ed.) London, pp. 279–296.

    Google Scholar 

  14. Fisher, M., Garcia, J. H., 1996, Neurology. 47: 884–888.

    Article  PubMed  CAS  Google Scholar 

  15. Furlan, A. J., 1995, Cleve Clin J Med. 62 (1): 6–8.

    PubMed  CAS  Google Scholar 

  16. Ginsberg. M. D., 1990, Revieves. 2: 68–93.

    Google Scholar 

  17. Ginsberg, M. D., 1994, New Strategies to Prevent Neural Damage from Ischemic Stroke. New York, pp. 1–34.

    Google Scholar 

  18. Ginsberg, M. D., Pulsinelli, W. A., 1994, Ann Neurol. 36: 553–554.

    Article  PubMed  CAS  Google Scholar 

  19. Hallenbeck, J. M., 1996, Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma. New York, pp. 27–31.

    Google Scholar 

  20. Hansen, A. J., 1985, Physiol Rev. 65: 101–148.

    PubMed  CAS  Google Scholar 

  21. Heiss, W.-D., Rosner G., 1983, Ann Neurol. 14: 294–301.

    Article  PubMed  CAS  Google Scholar 

  22. Heiss, W.-D., Graf, R., 1994, Curr Opin Neurobiol. 1: 11–19.

    Google Scholar 

  23. Heiss, W.-D., Huber, M., Fink, G. R., et al., 1992, J Cerebr Blood Flow Metab. 12: 193–203.

    Article  CAS  Google Scholar 

  24. Heiss, W.-D., Thiel, A., Grond, M., Graf, R., 2000, Stroke. 31 (4): 984–986.

    Google Scholar 

  25. Hossmann, K. A., 1993, Progr Brain Res. 96: 161–177.

    Article  CAS  Google Scholar 

  26. Hossmann, K. A., 1993, Resuscitation. 26: 225–235.

    Article  PubMed  CAS  Google Scholar 

  27. Hossmann, K. A., 1994, Ann Neurol. 36: 557–565.

    Article  PubMed  CAS  Google Scholar 

  28. Hossmann, K. A., 1994, Brain Pathol. 4: 23–36.

    Article  PubMed  CAS  Google Scholar 

  29. Iadecola, C., 1998, Cerebral circulatory dysregulation in ischemia. In Cerebrovascular Diseases (Ginsberg, M. D., Bogousslavsky, J., eds.) Blackwell, MA, Cambridge, pp. 319–332.

    Google Scholar 

  30. Iadecola, C., 1999, Mechanisms of cerebral ischemic damage. In Cerebral Ischemia (Walz, W., ed.) Humana Press, New Jersey, Totowa, pp. 3–33.

    Chapter  Google Scholar 

  31. Iadecola, C., Zhang, F., Nogawa, S., Ross, M. E., 1998, Post-ischernic gene expression and cerebral ischemic damage: role of inducible nitric oxide synthase. In Frontiers in Cerebrovascular Disease: Mechanisms, Diagnosis and Treatment (Robertson, J. T., Nowak, T. S., eds.) Futura Publications, New York, pp. 299–313.

    Google Scholar 

  32. Isayama, K., Pilts, L. H., Nishimura, M. C., 1991, Stroke. 22: 1394–1398.

    Article  PubMed  CAS  Google Scholar 

  33. Ito, U., Ohno, K., Nakamura, R., et al., 1979, Stroke. 10: 542–547.

    Article  PubMed  CAS  Google Scholar 

  34. Jacewicz, M., Kiessling, M., PulsineIli, W. A., 1986, J Cerebr Blood Flow Metab. 6: 263–272.

    Article  CAS  Google Scholar 

  35. Jones, T. H., Morawetz, R. B., Crowell, R. M., 1981, J Neurosurg. 54: 773–782.

    Article  PubMed  CAS  Google Scholar 

  36. Jones, S. C; Perez-Trepichio, A. D., Xue, M., et al., 1994, Acta Neurochir Suppl. 60 (-HD-): 207–210.

    PubMed  CAS  Google Scholar 

  37. Kirino, T., 1982, Brain Res. 239: 57–69.

    Article  PubMed  CAS  Google Scholar 

  38. Kirino, T., Sano, K., 1984, Acta Neuropathol. 62: 209–218.

    Article  PubMed  CAS  Google Scholar 

  39. Kirino, T., Tamura, A., Sano, K., 1984, Acta Neuropathol. 64: 139–147.

    Article  PubMed  CAS  Google Scholar 

  40. Macfarlane, R., Tasdemiroglu, E., Moskowitz, M. A., et al., 1991, J Cerebr Blood Flow Metab. II: 261–271.

    Google Scholar 

  41. Marchal, G., Beaudoin, V., Rioux, P., et al., 1996, Stroke. 27: 599–606.

    Article  PubMed  CAS  Google Scholar 

  42. Matsumoto, K., Yamada, K., Kohmura, E., et al., 1994, Neurol Res. 16 (6): 460–464.

    PubMed  CAS  Google Scholar 

  43. Matsumoto, K., Yamamoto, K., Hamburger, H. A., et al., 1987, Maya Clinic Proc. 62: 460–472.

    Article  CAS  Google Scholar 

  44. McCord, J. M., 1985, N Engl J Med. 312: 159–163.

    Article  PubMed  CAS  Google Scholar 

  45. Mies, G., Ishimaru, S., Xie, Y., et al., 1991, J Cerebr Blood Flow Metab. 11: 753–761.

    Article  CAS  Google Scholar 

  46. Ozyurt, E., 1988, J Cerebr Blood Flow Metab. 8: 138–143.

    Article  CAS  Google Scholar 

  47. Pappata, S., Fiorelli, M., Ronnel, T., et al., 1993, J Cerebr Blood Flow Metab. 13: 416–424.

    Article  CAS  Google Scholar 

  48. Pulsineili, W. A., 1992, Proc Natl Acad Sci USA. 89: 10499–10503.

    Google Scholar 

  49. Pulsinelli, W. A., Brierley, J., Plum, F., 1982, Ann Neurol, pp. 491–498.

    Google Scholar 

  50. Scheinberg, P., 1991, Neurology. 41: 1867–1873.

    Article  PubMed  CAS  Google Scholar 

  51. Siesjo, B. K., 1992, J Neurosurg. 77: 169–184.

    Article  PubMed  CAS  Google Scholar 

  52. Skvortsova, V. I., 1993, Clinical and Neurophysiological Monitoring and Metabolic Therapy in Acute Period of Cerebral Ischemic Stroke. Doctoral dissertation. Moscow, 379 (in Russian).

    Google Scholar 

  53. Tanahashi, N., 1988, Cerebral microvascular reserve for hyperemia. In Cerebral Hyperemia and Ischemia (Tomita, M., Sawada, T., Naritomi, H., Heiss, W.-D., eds.) Excerpta Medica, ICS 764, Amsterdam, pp. 173–182.

    Google Scholar 

  54. Tomita, M., 1988, Significance of cerebral blood volume. In Cerebral Hyperemia and Ischemia (Tomita, M., Sawada, T., Naritomi, H., Heiss, W.-D., eds.) Excerpta Medica, ICS 764, Amsterdam, pp. 3–31.

    Google Scholar 

  55. Tomita, M., 1993, Microcirculatory stasis in the brain. In Microcirculatory Stasis in the Brain (Tomita, M., Mchedlishvili, G., Rosenblum, W. I., Heiss, W.-D., Fukuuchi, Y., eds.) Excerpta Medica, ICS 1031, Amsterdam, pp. 1–7.

    Google Scholar 

  56. Tomita, M., Fukuuchi, Y., 1996, Acta Neurochir. 66: 32–39.

    CAS  Google Scholar 

  57. Touzani, A., Young, A. R., Derlon, J. M., et al., 1995, Stroke. 26: 12–21.

    Article  Google Scholar 

  58. Twichell, T. E., 1951, Brain. 74: 443–480.

    Article  Google Scholar 

  59. Warach, S., Gaa, J., Siewert, B., et al., 1995, Ann Neurol. 37: 231–241.

    Article  PubMed  CAS  Google Scholar 

  60. Warlow, C. P., Dennis, M. S., van Gijn, J., et al., 1996, Stroke. A Practical Guide to Management. Blackwell Science Ltd, Oxford, 6.

    Google Scholar 

  61. Welch, K. M. A., Windham, J., Knight, R. A., et al., 1995, Stroke. 26: 1983–1989.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Russian State Medical University, Moscow, Russia

    Eugene Gusev & Veronica I. Skvortsova

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  1. Eugene Gusev
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  2. Veronica I. Skvortsova
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Gusev, E., Skvortsova, V.I. (2003). Hemodynamic Events Associated with Acute Focal Brain Ischemia and Reperfusion. Ischemic Penumbra. In: Brain Ischemia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9248-2_2

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  • DOI: https://doi.org/10.1007/978-1-4419-9248-2_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4857-3

  • Online ISBN: 978-1-4419-9248-2

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