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Biodiversity of Phenylethanoid Glycosides

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Biodiversity

Abstract

Phenylethanoid glycosides are a group of natural products widely distributed in the plant kingdom, most of which have been isolated from medicinal plants, and their patterns of distrubition have been suggested to be valuable taxonomic markers. The most widely studied families are Scrophulariaceae, Oleaceae, Plantaginaceae, Lamiaceae and Orobanchaceae1,2. Structurally, they are characterized as caffeic acid and hydroxyphenylethyl moieties attached to a ß-glucopyranose unit by ester and glycosidic linkages, respectively. Allose, arabinose, apiose, galactose, lyxose, rhamnose and xylose may also be attached to the glucose residue. Although in most cases glucose is the core of the molecule, it is replaced by allose in some compounds such as magnolosides A, B and C3. Since most of them contain caffeic acid as acyl moiety, they are also termed as caffeic acid glycoside esters, phenylpropanoid glycosides or caffeoyl phenylethanoid glycosides. The most prevalent compound is acteoside (1 = verbascoside, kusaginin, orabanchin), 3,4-dihydroxyphenethyl-[α-L-rhamnopyranosyl (1→3)]-4’-O-caffeoyl-ß-D-glucopyranoside. This compound was first isolated fromVerbascum sinuatumand named as verbascoside. However

[1] Acteoside (= Verbascoside)

the complete structure of acteoside was first reported at 19684.

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Authors and Affiliations

  1. Department of Pharmacognosy, Hacettepe University Faculty of Pharmacy, 06100, Ankara, Turkey

    İhsan Çaliş

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  1. İhsan Çaliş
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  1. Gazi University, Ankara, Turkey

    Bilge Şener

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Çaliş, İ. (2002). Biodiversity of Phenylethanoid Glycosides. In: Şener, B. (eds) Biodiversity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9242-0_15

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  • DOI: https://doi.org/10.1007/978-1-4419-9242-0_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4855-9

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