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IL-4-Induced Lipid Mediators Class Switching in Human Normal Mononuclear Phagocytes

  • Angelo Sala
  • Mirella Profita
  • Liboria Siena
  • Peter M. Henson
  • Robert C. Murphy
  • Alessandra Paternò
  • Anna Bonanno
  • Loredana Riccobono
  • Angela Mirabella
  • Giovanni Bonsignore
  • A. Maurizio Vignola
Chapter
  • 141 Downloads
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 525)

Abstract

Leukotrienes (LT) are important molecules arising from arachidonic acid, knokn to play an important role in inflammatory reactions [1]. Their synthesis is limited to a restricted number of cell involved in the inflammatory response, such as mast cells, neutrophils, eosinophils and monocyte/macrophages.

Keywords

Chronic Obstructive Pulmonary Disease Mast Cell Chronic Bronchitis Human Monocyte Lipid Mediator 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Angelo Sala
    • 1
  • Mirella Profita
    • 2
  • Liboria Siena
    • 2
  • Peter M. Henson
    • 3
  • Robert C. Murphy
    • 3
  • Alessandra Paternò
    • 2
  • Anna Bonanno
    • 2
  • Loredana Riccobono
    • 2
  • Angela Mirabella
    • 4
  • Giovanni Bonsignore
    • 4
  • A. Maurizio Vignola
    • 4
  1. 1.Dipartimento di Scienze Famacologiche and Center for Cardiopulmonary PharmacologyUniversità di MilanoMilanItaly
  2. 2.Centro Nazionale delle RicercheIstituto di Fisiopatologia RespiratoriaPalermoItaly
  3. 3.National Jewish Medical and Research CenterDenverUSA
  4. 4.Istituto di Medicina Generale e PneumologiaUniversité di PalermoPalermoItaly

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