IL-4-Induced Lipid Mediators Class Switching in Human Normal Mononuclear Phagocytes
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Leukotrienes (LT) are important molecules arising from arachidonic acid, knokn to play an important role in inflammatory reactions . Their synthesis is limited to a restricted number of cell involved in the inflammatory response, such as mast cells, neutrophils, eosinophils and monocyte/macrophages.
KeywordsChronic Obstructive Pulmonary Disease Mast Cell Chronic Bronchitis Human Monocyte Lipid Mediator
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- 1.Sala A, S Zarini, M Bolla. Leukotrienes: lipid bioeffectors of inflammatory reactions. Biochemistry (Moscow) 1998; 63(1): pp. 84–92.Google Scholar
- 5.Bradley BL et al. Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness. J Allergy Clin Immunol 1991;88(4): 661–674.PubMedCrossRefGoogle Scholar
- 9.Profita M et al. 15(S)-HETE release and reincorporation modulate LTB4 production and neutrophil Chemotaxis in chronic bronchitis. Am J Physiol, 2000; 279(4): CI 249–C1258.Google Scholar