Advertisement

Effects of In Vitro Exposure to Carbon Dioxide on the Expression of Apoptosis-Associated Genes in Human Peritoneal Fibroblasts

  • Ângela Mara Bentes de Souza
  • Christine May Briton-Jones
  • Chi Chiu Wang
  • Christopher John Haines
  • Michael Scott Rogers
Chapter
  • 138 Downloads
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 525)

Abstract

The peritoneum is composed of a superficial layer of mesothelial cells with a submesothelial layer that contains fibroblasts, macrophages, and blood vessels. Fibroblasts invade wounds in the first few days of healinG. They have multiple functions in wound repair, including collagen synthesis, extracellular matrix reorganization, and wound contraction leading to mature scar formation [1].

Keywords

Mesothelial Cell Uterine Fibroid Wound Contraction Tumor Necrosis Factor Release Fibroblast Cell Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    diZerega GS. The peritoneum and its response to surgical injury. Prog Clin Biol Res 1990; 358: 1–11.PubMedGoogle Scholar
  2. 2. United States Pharmacopeia and National Formulary and Supplements, Vol. XXI-NF. Washington, DC: U.S. Government Printing Office, 1984.Google Scholar
  3. 3.
    West MA, Hackam DJ, Baker J, Rodrigues JL, Bellinghan J, Rotstein OD. Mechanism of Decreased In Vitro Murine Macrophage Cytokine Release After Exposure to Carbon Dioxide: Relevance to Laparoscopic Surgery. Ann Surg 1997; 226: 179–190.PubMedCrossRefGoogle Scholar
  4. 4.
    Molinas CR, Mynbaev OA, Pauwels A, Novak P, Koninckx PR. Peritoneal mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation in a laparoscopic mouse model. Fertil Steril 2001; 176: 560–567.CrossRefGoogle Scholar
  5. 5.
    Laflon B, Pasaro E, Mendez J. Effects of styrene-7,8-oxide over p53, p21, bc1-2 and bax expression in human lymphocyte cultures. Mutagenesis 2001; 16: 127–132.CrossRefGoogle Scholar
  6. 6.
    Zhong LT, Sarafian T, Kane DJ, Charles AC, Man SP, Edwards RH, Bredesen DE. Bc1-2 inhibits death of central neural cells induced by multiple agents. Proc Natl Acad Sci USA 1993; 90: 4533–4537.PubMedCrossRefGoogle Scholar
  7. 7.
    Bentes de Souza AM, Rogers MS, Wang CC, Yuen PM, Ng PS. Comparison of peritoneal oxidative stress during laparoscopy and laparotomy. J Am Assoc Gynecol Laparosc 2003; 10: 65–74PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Ângela Mara Bentes de Souza
    • 1
  • Christine May Briton-Jones
    • 1
  • Chi Chiu Wang
    • 1
  • Christopher John Haines
    • 1
  • Michael Scott Rogers
    • 1
  1. 1.Department of Obstetrics & GynaecologyChinese University of Hong KongHong Kong SARHong Kong

Personalised recommendations