Prostaglandin F2α Protected Cultured Madin-Darby Canine Kidney Cells from the Development of Apoptosis Induced by 12-O-Tetradecanoyl Phorbol-β- Acetate and Stimulated Synergistically with Nordihydroguaiaretic Acid
- 139 Downloads
The arachidonate cascade generates a series of lipid mediators to regulate various biological events through cyclooxygenase (COX) and lipoxygenase (LOX) pathways [,]. In addition, both COX and LOX metabolites were reported to play a dual role in regulating cell survival and death depending on certain types of cells or signalling molecules [1,]. However, the cellular mechanism by which these eicosanoids mediate the induction or suppression of apoptosis remains still unclear.
KeywordsMDCK Cell Chicken Embryo Fibroblast Calcium Ionophore A23187 Nordihydroguaiaretic Acid Darby Canine Kidney
Unable to display preview. Download preview PDF.