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Sperm Nuclear DNA Damage in the Human

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Advances in Male Mediated Developmental Toxicity

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 518))

Abstract

The male partner is now recognized as the single most common contributor to a couple’s reason for infertility, with sperm defects accounting for around 30–50% of cases presenting to infertility clinics (Hull, 1992). A standard semen analysis, in particular the assessment of sperm concentration and motility, should therefore always be viewed as a mandatory test for inclusion in the investigation of the infertile couple (WHO, 1992; WHO,1999). A semen analysis, however, only helps to provide broad diagnostic categories.

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Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Yale University School of Medicine, Connecticut, USA

    Denny Sakkas

  2. Department of Animal Biology, University of Modena and Reggio Emilia, Italy

    Gian Carlo Manicardi

  3. Institute of Biology and Genetics, University of Ancona, Italy

    Davide Bizzaro

Authors
  1. Denny Sakkas
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  2. Gian Carlo Manicardi
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  3. Davide Bizzaro
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Editor information

Editors and Affiliations

  1. McGill University, Montreal, Quebec, Canada

    Bernard Robaire  & Barbara F. Hales  & 

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© 2003 Springer Science+Business Media New York

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Sakkas, D., Manicardi, G.C., Bizzaro, D. (2003). Sperm Nuclear DNA Damage in the Human. In: Robaire, B., Hales, B.F. (eds) Advances in Male Mediated Developmental Toxicity. Advances in Experimental Medicine and Biology, vol 518. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9190-4_7

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  • DOI: https://doi.org/10.1007/978-1-4419-9190-4_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4829-0

  • Online ISBN: 978-1-4419-9190-4

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