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Pseudomonas aeruginosa Interactions with Host Cells

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Pseudomonas

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Abstract

The opportunistic nature of many different Pseudomonas aeruginosa infections leaves patients withcompromised immune systems highlysusceptible to infection. Common forms of immunesuppression leading to P. aeruginosa infectionincludeburn and traumawounds, diseasessuch as AIDS, or chemotherapeutic treatments that affect leukocyte numbers and functions. Cystic fibrosis (CF) patients develop chronic life-threatening lung infections with P. aeruginosa and can be considered to have defective innate and acquired immunity to this organism. Althoughrare, peoplewhouse extended-wear soft contact lenses are at an increasedrisk for acute ulcerative keratitis.

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  1. Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, USA

    Gerald B. Pier

  2. Department of Microbiology, University of Virginia Health Sciences Center, Charlottesville, VA, 22908, USA

    Joanna B. Goldberg

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  1. CSIC, Granada, Spain

    Juan-Luis Ramos

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Pier, G.B., Goldberg, J.B. (2004). Pseudomonas aeruginosa Interactions with Host Cells. In: Ramos, JL. (eds) Pseudomonas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9086-0_17

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