Pseudomonas pp 505-545 | Cite as

Pseudomonas aeruginosa Interactions with Host Cells

  • Gerald B. Pier
  • Joanna B. Goldberg


The opportunistic nature of many different Pseudomonas aeruginosa infections leaves patients withcompromised immune systems highlysusceptible to infection. Common forms of immunesuppression leading to P. aeruginosa infectionincludeburn and traumawounds, diseasessuch as AIDS, or chemotherapeutic treatments that affect leukocyte numbers and functions. Cystic fibrosis (CF) patients develop chronic life-threatening lung infections with P. aeruginosa and can be considered to have defective innate and acquired immunity to this organism. Althoughrare, peoplewhouse extended-wear soft contact lenses are at an increasedrisk for acute ulcerative keratitis.


Epithelial Cell Cystic Fibrosis Pseudomonas Aeruginosa Cystic Fibrosis Transmembrane Conductance Regulator Airway Epithelial Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Gerald B. Pier
    • 1
  • Joanna B. Goldberg
    • 2
  1. 1.Channing Laboratory, Department of MedicineBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA
  2. 2.Department of MicrobiologyUniversity of Virginia Health Sciences CenterCharlottesvilleUSA

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