Criteria for Diagnosis and Classification of Melanoma

  • Raymond L. Barnhill


The overwhelming majority of melanomas begin as intraepidermal or intraepithelial proliferations, which may or may not have some relationship to a melanocytic nevus (9–37) (Fig. 1A,B). Estimates of the frequency of melanomas developing in continuity with a nevus of any kind vary widely; approximately a third of melanomas have nevus remnants (38–40). The duration of this intraepidermal phase ranges from months to many years, during which these proliferative lesions show progressive degrees of architectural and cytologic atypicality (41).


Cytologic Atypia Breslow Thickness Papillary Dermis Melanocytic Nevus Nodular Melanoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Raymond L. Barnhill
    • 1
  1. 1.Departments of Dermatology and PathologyUniversity of MiamiMiamiUSA

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