Abstract
Two major biochemical functions of mammalian cells are discussed in this chapter. One is the degradation of metabolite s to generate energy for cellular processes and the second is the transport of building blocks during synthesis and breakdown of macromolecules. The two functions are discussed together because there are significant overlaps between them. For example, glucose is the main cellular energy metabolite but in addition is a building block of glycogen, and glucose derivatives are building blocks of glycoproteins; amino acids are the building blocks of proteins and are the main energy metabolites during fasting and starvation. The overlap between energy metabolism and synthesis/degradation of macromolecules also becomes apparent in the phenotype of transporter pathologies, which frequently affect both energy metabolism and synthesis of cellular components.
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Bröer, S. (2003). Introduction. In: Bröer, S., Wagner, C.A. (eds) Membrane Transporter Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9023-5_9
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DOI: https://doi.org/10.1007/978-1-4419-9023-5_9
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