WinSAAM: Application and Explanation of Use

  • Janet A. Novotny
  • Peter Greif
  • Raymond C. Boston
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 537)


The WinSAAM modeling software is an integrated package of mathematical, simula-tion, and graphical tools for analysis of biokinetic data. WinSAAM is the Windows version of SAAM, the Simulation, Analysis, and Modeling computer program. SAAM, a collection of scientific subroutines, was created in the 1950s by Dr. Mones Berman to meet the mathematical needs of his research program. Over the decades, SAAM has been continually developed and enhanced (Berman and Weiss, 1978; Boston et al., 1981), and today, WinSAAM is an elegant and powerful tool for mathematical and compartmental modeling.


Input File Transfer Parameter Model Diagram Order Linear Differential Equation Optimize Parameter Estimate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Herman, M., and Weiss, M.F., 1978, SAAM Manual, DHEW Publ. (NIH) 78–180, U.S. Government Printing Office, Washington, DC.Google Scholar
  2. Boston, R.C., Greif, P.C., and Berman, M., 1981, Conversational SAAM-an interactive program for the kinetic analysis of biological systems, Comput. Prog. Biomed. 13:111–119.CrossRefGoogle Scholar
  3. France, J., Thornley, J.H.M., and Beever, D.E., 1982, A mathematical model of the rumen, J. Agric. Sci. Camb. 99:343–353.CrossRefGoogle Scholar
  4. MLAB User’s Guide, p. 316, 1997, Civilized Software, Inc., Bethesda.Google Scholar
  5. Wastney, M.E., Patterson, B.H., Linares, O.A., Grief, P.C., and Boston, R.C., 1999, Investigating Biological Systems Using Modeling: Strategies and Software, Academic Press, New York.Google Scholar

Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Janet A. Novotny
    • 1
  • Peter Greif
    • 2
  • Raymond C. Boston
    • 3
  1. 1.Beltsville Human Nutrition Research CenterUSDA, BHNRC, DHPLBeltsville
  2. 2.Laboratory of Experimental and Computational BiologyNational Cancer InstituteBethesda
  3. 3.University of PennsylvaniaClinical Studies Department, New Bolton CenterKennett Square

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